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1-3 of 3
Keywords: hedgehog
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (8): 953–970.
Published: 29 April 2019
...Masaru Katoh Hedgehog signals are transduced through Patched receptors to the Smoothened (SMO)-SUFU-GLI and SMO-Gi-RhoA signaling cascades. MTOR-S6K1 and MEK-ERK signals are also transduced to GLI activators through post-translational modifications. The GLI transcription network up-regulates target...
Articles
Imad Al Ghouleh, Sanghamitra Sahoo, Daniel N. Meijles, Jefferson H. Amaral, Daniel S. de Jesus, John Sembrat, Mauricio Rojas, Dmitry A. Goncharov, Elena A. Goncharova, Patrick J. Pagano
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (15): 2019–2035.
Published: 17 July 2017
... morphogenetic protein (BMP) antagonist Gremlin1 (Grem1). In HPAEC, hypoxia induced Nox1 subunit expression, assembly, and oxidase activity leading to elevation in sonic hedgehog (SHH) and Grem1 expression. Nox1 gene silencing abrogated this cascade. Moreover, loss of either Nox1, SHH or Grem1 attenuated hypoxia...
Articles
Steve S. Choi, Lee C. Claridge, Ravi Jhaveri, Marzena Swiderska-Syn, Paul Clark, Ayako Suzuki, Thiago A. Pereira, Zhiyong Mi, Paul C. Kuo, Cynthia D. Guy, Fausto E. L. Pereira, Anna Mae Diehl, Keyur Patel, Wing-Kin Syn
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (12): 845–855.
Published: 26 February 2014
...Steve S. Choi; Lee C. Claridge; Ravi Jhaveri; Marzena Swiderska-Syn; Paul Clark; Ayako Suzuki; Thiago A. Pereira; Zhiyong Mi; Paul C. Kuo; Cynthia D. Guy; Fausto E. L. Pereira; Anna Mae Diehl; Keyur Patel; Wing-Kin Syn OPN (osteopontin)) is a Hh (Hedgehog)-regulated cytokine that is up-regulated...
