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Articles

Oral oestrogen reverses ovariectomy-induced morning surge hypertension in growth-restricted mice

Sarah E. Haskell, Veronica Peotta, Benjamin E. Reinking, Catherine Zhang, Vivian Zhu, Elizabeth J. Kenkel, Robert D. Roghair

Clin Sci (Lond) (2016) 130 (8): 613–623.

DOI: https://doi.org/10.1042/CS20150693

Published: 08 March 2016

... dysfunction and ultimately demonstrate the protective effects of oestrogen replacement therapy. autonomic developmental origins echocardiography heart rate variability • Sexual dimorphism has been observed in the developmental origins of cardiovascular disease, with young adult women...

View article titled, Oral oestrogen reverses ovariectomy-induced morning surge hypertension in growth-restricted mice

Articles

Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

Emma O'Donnell, Jack M. Goodman, Beverly L. Morris, John S. Floras, Paula J. Harvey

Clin Sci (Lond) (2015) 129 (10): 885–893.

DOI: https://doi.org/10.1042/CS20150209

Published: 01 September 2015

... exercise heart rate variability oestrogen • Low HRV is associated with increased risk of cardiac events in both healthy and diseased populations. Oestrogen deficiency due to menopause is associated with attenuated HRV in association with decreased vagal modulation. We examined the influence...

View article titled, Augmented vagal heart rate modulation in active hypoestrogenic pre-menopausal women with functional hypothalamic amenorrhoea

Articles

Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease

Djordje G. Jakovljevic, Kate Hallsworth, Pawel Zalewski, Christian Thoma, Jacek J. Klawe, Christopher P. Day, Julia Newton, Michael I. Trenell

Clin Sci (Lond) (2013) 125 (3): 143–149.

DOI: https://doi.org/10.1042/CS20120684

Published: 12 April 2013

... authors. Correspondence: Dr Djordje Jakovljevic (email djordje.jakovljevic@newcastle.ac.uk. ). 17 12 2012 22 2 2013 5 3 2013 5 3 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 blood pressure variability exercise heart rate variability...

View article titled, Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease

Articles

You may need the vagus nerve to understand pathophysiology and to treat diseases

Marijke De Couck, Boris Mravec, Yori Gidron

Clin Sci (Lond) (2012) 122 (7): 323–328.

DOI: https://doi.org/10.1042/CS20110299

Published: 07 December 2011

... reactions and excessive sympathetic responses, all of which are inhibited by vagal nerve activity. Efferent vagal activity that can be non-invasively measured by HRV (heart rate variability), derived from an ECG, is inversely related to all three basic mechanisms, to various risk factors (e.g. diabetes...

View article titled, You may need the vagus nerve to understand pathophysiology and to treat diseases

Articles

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

Matthijs Kox, Jan C. Pompe, Johannes G. van der Hoeven, Cornelia W. Hoedemaekers, Peter Pickkers

Clin Sci (Lond) (2011) 121 (5): 215–222.

DOI: https://doi.org/10.1042/CS20110027

Published: 20 May 2011

...Matthijs Kox; Jan C. Pompe; Johannes G. van der Hoeven; Cornelia W. Hoedemaekers; Peter Pickkers HRV (heart rate variability) analysis is a widely employed method to assess cardiac autonomic nervous system activity. Accurate HRV measurement is critical to its value as a diagnostic and prognostic...

View article titled, Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

Articles

Regulation of subcutaneous adipose tissue blood flow is related to measures of vascular and autonomic function

Jun-ichi Funada, A. Louise Dennis, Rachel Roberts, Fredrik Karpe, Keith N. Frayn

Clin Sci (Lond) (2010) 119 (8): 313–322.

DOI: https://doi.org/10.1042/CS20100066

Published: 06 July 2010

... is a marker of atherosclerotic risk, so we also assessed relationships between ATBF and a marker of atherosclerosis, common carotid artery IMT (intima-media thickness). As ATBF is responsive to sympatho-adrenal stimuli, we also investigated relationships with HRV (heart rate variability). A total of 79...

View article titled, Regulation of subcutaneous adipose tissue blood flow is related to measures of vascular and autonomic function

Articles

Reliability of heart rate variability measurements in patients with a history of myocardial infarction

Roberto Maestri, Grzegorz Raczak, Ludmila Danilowicz-Szymanowicz, Antoni Torunski, Adam Sukiennik, Jacek Kubica, Maria Teresa La Rovere, Gian Domenico Pinna

Clin Sci (Lond) (2010) 118 (3): 195–201.

DOI: https://doi.org/10.1042/CS20090183

Published: 01 February 2010

...Roberto Maestri; Grzegorz Raczak; Ludmila Danilowicz-Szymanowicz; Antoni Torunski; Adam Sukiennik; Jacek Kubica; Maria Teresa La Rovere; Gian Domenico Pinna Despite a well-established prognostic value in cardiac patients, HRV (heart rate variability) indexes have been used little in the clinical...

View article titled, Reliability of heart rate variability measurements in patients with a history of myocardial infarction

Articles

QT interval prolongation and decreased heart rate variability in cirrhotic patients: relevance of hepatic venous pressure gradient and serum calcium

Simonetta Genovesi, Daniela M. Prata Pizzala, Massimo Pozzi, Laura Ratti, Maria Milanese, Federico Pieruzzi, Antonio Vincenti, Andrea Stella, Giuseppe Mancia, Marco Stramba-Badiale

Clin Sci (Lond) (2009) 116 (12): 851–859.

DOI: https://doi.org/10.1042/CS20080325

Published: 14 May 2009

... patients underwent a 24-h ECG Holter recording. The 24-h mean of QT intervals corrected for heart rate (termed QTc) and the slope of the regression line QT/RR were calculated. HRV (heart rate variability), plasma calcium and potassium concentration and HVPG (hepatic venous pressure gradient) were measured...

View article titled, QT interval prolongation and decreased heart rate variability in cirrhotic patients: relevance of hepatic venous pressure gradient and serum calcium

Articles

Normative values, reliability and sample size estimates in heart rate variability

Gavin Sandercock

Clin Sci (Lond) (2007) 113 (3): 129–130.

DOI: https://doi.org/10.1042/CS20070137

Published: 02 July 2007

...Gavin Sandercock HRV (heart rate variability) is a non-invasive maker of cardiac autonomic modulation utilized in many hundreds of scientific studies each year. The reliability of heart rate variability has been frequently investigated yet remains poorly quantified. Assessing the reliability...

View article titled, Normative values, reliability and sample size estimates in heart rate variability

Articles

Heart rate variability measures: a fresh look at reliability

Gian Domenico Pinna, Roberto Maestri, Antoni Torunski, Ludmila Danilowicz-Szymanowicz, Malgorzata Szwoch, Maria Teresa La Rovere, Grzegorz Raczak

Clin Sci (Lond) (2007) 113 (3): 131–140.

DOI: https://doi.org/10.1042/CS20070055

Published: 02 July 2007

...Gian Domenico Pinna; Roberto Maestri; Antoni Torunski; Ludmila Danilowicz-Szymanowicz; Malgorzata Szwoch; Maria Teresa La Rovere; Grzegorz Raczak Despite its extensive use in physiological and clinical research, the analysis of HRV (heart rate variability) is still poorly supported by rigorous...

View article titled, Heart rate variability measures: a fresh look at reliability

Articles

C-reactive protein modulates vagal heart rate control in patients with coronary artery disease

Robert P. Nolan, Graham J. Reid, Peter H. Seidelin, Herbert K. Lau

Clin Sci (Lond) (2007) 112 (8): 449–456.

DOI: https://doi.org/10.1042/CS20060132

Published: 13 March 2007

...Robert P. Nolan; Graham J. Reid; Peter H. Seidelin; Herbert K. Lau Systemic inflammation is associated with sympathetic cardiac activation and decreased HRV (heart rate variability) in subjects at high risk of CAD (coronary artery disease). In the present study, we examined the influence...

View article titled, C-reactive protein modulates vagal heart rate control in patients with coronary artery disease

Articles

New evidence of baroreflex dysfunction in congenital central hypoventilation syndrome

Philippe van de BORNE

Clin Sci (Lond) (2005) 108 (3): 215–216.

DOI: https://doi.org/10.1042/CS20040360

Published: 18 February 2005

...Philippe van de BORNE In this issue of Clinical Science , Trang and co-workers report the results of short-term blood pressure and heart rate variability measurements in patients with congenital central hypoventilation syndrome (CCHS). The results reveal that these young patients disclose signs...

View article titled, New evidence of baroreflex dysfunction in congenital central hypoventilation syndrome

Articles

Short-term blood pressure and heart rate variability in congenital central hypoventilation syndrome (Ondine's curse)

Ha TRANG, Arlette GIRARD, Dominique LAUDE, Jean-Luc ELGHOZI

Clin Sci (Lond) (2005) 108 (3): 225–230.

DOI: https://doi.org/10.1042/CS20040282

Published: 18 February 2005

...Ha TRANG; Arlette GIRARD; Dominique LAUDE; Jean-Luc ELGHOZI The effect of CCHS (congenital central hypoventilation syndrome, or Ondine's curse) on short-term BP (blood pressure) and HR (heart rate) variability was evaluated in 16-year-old subjects presenting a form of CCHS requiring night...

View article titled, Short-term blood pressure and heart rate variability in congenital central hypoventilation syndrome (Ondine's curse)

Articles

Cardiac autonomic activity and Type II diabetes mellitus

Daniela MANZELLA, Giuseppe PAOLISSO

Clin Sci (Lond) (2005) 108 (2): 93–99.

DOI: https://doi.org/10.1042/CS20040223

Published: 21 January 2005

...Daniela MANZELLA; Giuseppe PAOLISSO CAN (cardiac autonomic neuropathy) is a common complication of diabetes. Meta-analyses of published data demonstrate that reduced cardiovascular autonomic function, as measured by heart rate variability, is strongly associated with an increased risk of silent...

View article titled, Cardiac autonomic activity and Type II diabetes mellitus

Articles

Factors influencing heart rate variability power spectral analysis during controlled breathing in patients with chronic heart failure or hypertension and in healthy normotensive subjects

Gianfranco PICCIRILLO, Damiano MAGRÌ, Camilla NASO, Silvia di CARLO, Antonio MOISÈ, Tiziana DE LAURENTIS, Alessia TORRINI, Sabrina MATERA, Marialuce NOCCO

Clin Sci (Lond) (2004) 107 (2): 183–190.

DOI: https://doi.org/10.1042/CS20030401

Published: 27 July 2004

...Gianfranco PICCIRILLO; Damiano MAGRÌ; Camilla NASO; Silvia di CARLO; Antonio MOISÈ; Tiziana DE LAURENTIS; Alessia TORRINI; Sabrina MATERA; Marialuce NOCCO A decreased LFP (low-frequency power) spectral component of HRV [HR (heart rate) variability] is a risk factor for sudden death in patients...

View article titled, Factors influencing heart rate variability power spectral analysis during controlled breathing in patients with chronic heart failure or hypertension and in healthy normotensive subjects

Articles

Heart rate increment: an electrocardiological approach for the early detection of obstructive sleep apnoea/hypopnoea syndrome

Frédéric ROCHE, Emilia SFORZA, David DUVERNEY, Jean-René BORDERIES, Vincent PICHOT, Odile BIGAIGNON, Gilles ASCHER, Jean-Claude BARTHÉLÉMY

Clin Sci (Lond) (2004) 107 (1): 105–110.

DOI: https://doi.org/10.1042/CS20040036

Published: 23 June 2004

... system ECG Holter monitoring heart rate variability obstructive sleep apnoea/hypopnoea syndrome Sleep-related breathing disorders are not only common [ 1 ], but also bear significant health consequences, since they may imply severe daytime repercussions [ 2 ], as well as increased cardiac...

View article titled, Heart rate increment: an electrocardiological approach for the early detection of obstructive sleep apnoea/hypopnoea syndrome

Articles

Increased high-frequency heart rate variability during insulin-induced hypoglycaemia in healthy humans

Hartmut SCHÄCHINGER, Johannes PORT, Stuart BRODY, Lilly LINDER, Frank H. WILHELM, Peter R. HUBER, Daniel COX, Ulrich KELLER

Clin Sci (Lond) (2004) 106 (6): 583–588.

DOI: https://doi.org/10.1042/CS20030337

Published: 01 June 2004

... 2004 The Biochemical Society 2004 autonomic nervous system glucose heart rate variability hypoglycaemia impedance cardiography Clinical Science (2004) 106, 583 588 (Printed in Great Britain) 583 Increased high-frequency heart rate variability during insulin-induced hypoglycaemia in healthy...

View article titled, Increased high-frequency heart rate variability during insulin-induced hypoglycaemia in healthy humans

Articles

Short- and long-term reproducibility of autonomic measures in supine and standing positions

M. A. KOWALEWSKI, M. URBAN

Clin Sci (Lond) (2004) 106 (1): 61–66.

DOI: https://doi.org/10.1042/CS20030119

Published: 01 January 2004

...M. A. KOWALEWSKI; M. URBAN Autonomic nervous tests and heart rate variability (HRV) have been used to assess cardiac autonomic function and to evaluate long-term prognosis. The aim of this study was to evaluate the short- and long-term reproducibility of HRV parameters and autonomic nervous tests...

View article titled, Short- and long-term reproducibility of autonomic measures in supine and standing positions

Articles

Cross-spectral analysis of cardiovascular parameters whilst supine may identify subjects with poor orthostatic tolerance

Giosuè GULLI, Victoria L. COOPER, Victoria CLAYDON, Roger HAINSWORTH

Clin Sci (Lond) (2003) 105 (1): 119–126.

DOI: https://doi.org/10.1042/CS20020322

Published: 01 July 2003

...Giosuè GULLI; Victoria L. COOPER; Victoria CLAYDON; Roger HAINSWORTH Correspondence: Dr Giosuè Gulli (e-mail GiosueGulli@yahoo.it ). 12 11 2002 26 2 2003 2 4 2003 2 4 2003 © 2003 The Biochemical Society 2003 baroreflex heart rate variability syncope...

View article titled, Cross-spectral analysis of cardiovascular parameters whilst supine may identify subjects with poor orthostatic tolerance

Articles

Advanced analysis of spontaneous baroreflex sensitivity, blood pressure and heart rate variability in patients with dilated cardiomyopathy

Hagen MALBERG, Niels WESSEL, Annett HASART, Karl-Josef OSTERZIEL, Andreas VOSS

Clin Sci (Lond) (2002) 102 (4): 465–473.

DOI: https://doi.org/10.1042/cs1020465

Published: 18 March 2002

...) and in healthy subjects (controls), as well as comparing the values of BRS parameters with parameters of heart rate variability (HRV) and blood pressure variability (BPV). ECG, continuous blood pressure and respiration curves were recorded for 30min in 27 DCM patients and 27 control subjects. The Dual Sequence...

View article titled, Advanced analysis of spontaneous baroreflex sensitivity, blood pressure and heart rate variability in patients with dilated cardiomyopathy

Articles

Nitric oxide and cardiac parasympathetic control in human heart failure

Saqib CHOWDHARY, G. Andre NG, Sarah L. NUTTALL, John H. COOTE, Hamish F. ROSS, Jonathan N. TOWNEND

Clin Sci (Lond) (2002) 102 (4): 397–402.

DOI: https://doi.org/10.1042/cs1020397

Published: 05 March 2002

... patients [NYHA class II-III; mean age 52 years (range 38-67 years)] and 12 age/sex-matched healthy control subjects [mean age 50 years (range 36-62 years)] were studied. Heart rate variability and baroreflex sensitivity were measured during inhibition of endogenous NO production with N G -monomethyl- l...

View article titled, Nitric oxide and cardiac parasympathetic control in human heart failure

Articles

Neuroendocrine changes during the evolution of doxorubicin-induced left ventricular dysfunction in adult lymphoma patients

Tapio NOUSIAINEN, Esko VANNINEN, Esa JANTUNEN, Jouko REMES, Eira RITANEN, Olli VUOLTEENAHO, Juha HARTIKAINEN

Clin Sci (Lond) (2001) 101 (6): 601–607.

DOI: https://doi.org/10.1042/cs1010601

Published: 26 October 2001

... ventriculography, frequency domain analysis of heart rate variability (HRV), and plasma noradrenaline and natriuretic peptide measurements were performed in 27 adult lymphoma patients at baseline and after cumulative doxorubicin doses of 200, 400 and 500mg/m 2 . The left ventricular ejection fraction (LVEF...

View article titled, Neuroendocrine changes during the evolution of doxorubicin-induced left ventricular dysfunction in adult lymphoma patients

Articles

Effects of angiotensin II (AT1) receptor blockade on cardiac vagal control in heart failure

J. C. VAILE, S. CHOWDHARY, F. OSMAN, H. F. ROSS, J. FLETCHER, W. A. LITTLER, J. H. COOTE, J. N. TOWNEND

Clin Sci (Lond) (2001) 101 (6): 559–566.

DOI: https://doi.org/10.1042/cs1010559

Published: 24 October 2001

... compared the effects of candesartan and placebo on baroreflex sensitivity and on heart rate variability at rest, during stress and during 24h monitoring. Acute effects were assessed 4h after oral candesartan (8mg) and chronic effects after 4 weeks of treatment (dose titrated to 16mg daily). The study group...

View article titled, Effects of angiotensin II (AT1) receptor blockade on cardiac vagal control in heart failure

Articles

Attenuated cardiac baroreflex in men with presyncope evoked by lower body negative pressure

Duminda N. WIJEYSUNDERA, Gary C. BUTLER, Shin-ichi ANDO, Michael J. POLLARD, Peter PICTON, John S. FLORAS

Clin Sci (Lond) (2001) 100 (3): 303–309.

DOI: https://doi.org/10.1042/cs1000303

Published: 31 January 2001

.... During the course of our investigation of sympathetic nervous system responses to lower body negative press- ure (LBNP) in healthy, middle-aged men, symptoms or Key words : baroreceptor reflex, central venous pressure, heart rate variability, microneurography, sympathetic nervous system. Abbreviations...

View article titled, Attenuated cardiac baroreflex in men with presyncope evoked by lower body negative pressure

Articles

Low-frequency heart rate variability: reproducibility in cardiac transplant recipients and normal subjects

S. W. LORD, R. R. SENIOR, M. DAS, A. M. WHITTAM, A. MURRAY, J. M. MCCOMB

Clin Sci (Lond) (2001) 100 (1): 43–46.

DOI: https://doi.org/10.1042/cs1000043

Published: 13 December 2000

...S. W. LORD; R. R. SENIOR; M. DAS; A. M. WHITTAM; A. MURRAY; J. M. MCCOMB Heart rate variability is a measure of autonomic nervous influence on the heart. It has been suggested that it could be used to detect autonomic reinnervation to the transplanted heart, but the reproducibility...

View article titled, Low-frequency heart rate variability: reproducibility in cardiac transplant recipients and normal subjects

Articles

Cardiocirculatory coupling during sinusoidal baroreceptor stimulation and fixed-frequency breathing

Cornelius KEYL, Martin DAMBACHER, Annette SCHNEIDER, Claudio PASSINO, Ulrike WEGENHORST, Luciano BERNARDI

Clin Sci (Lond) (2000) 99 (2): 113–124.

DOI: https://doi.org/10.1042/cs0990113

Published: 10 July 2000

... ). 27 10 1999 6 3 2000 31 3 2000 The Biochemical Society and the Medical Research Society © 2000 2000 autonomic nervous system baroreceptors blood pressure heart rate variability respiration 113Clinical Science (2000) 99, 113 124 (Printed in Great Britain...

View article titled, Cardiocirculatory coupling during sinusoidal baroreceptor stimulation and fixed-frequency breathing

Articles

Effects of insulin on the cardiac autonomic nervous system in insulin-resistant states

Giuseppe PAOLISSO, Daniela MANZELLA, Maria Rosaria RIZZO, Michelangela BARBIERI, Gina VARRICCHIO, Antonio GAMBARDELLA, Michele VARRICCHIO

Clin Sci (Lond) (2000) 98 (2): 129–136.

DOI: https://doi.org/10.1042/cs0980129

Published: 04 January 2000

... by continuous recording of heart rate variability by the Holter technique and by venous occlusion plethysmography respectively. At baseline, healthy subjects had the highest values for total spectral power and the low-frequency (LF) component, and the lowest value for the high-frequency (HF) component...

View article titled, Effects of insulin on the cardiac autonomic nervous system in insulin-resistant states

Articles

Baseline heart rate variability in healthy centenarians: differences compared with aged subjects (>75 years old)

Giuseppe PAOLISSO, Daniela MANZELLA, Michelangela BARBIERI, Maria Rosaria RIZZO, Antonio GAMBARDELLA, Michele VARRICCHIO

Clin Sci (Lond) (1999) 97 (5): 579–584.

DOI: https://doi.org/10.1042/cs0970579

Published: 28 September 1999

...Giuseppe PAOLISSO; Daniela MANZELLA; Michelangela BARBIERI; Maria Rosaria RIZZO; Antonio GAMBARDELLA; Michele VARRICCHIO Healthy centenarians have better anthropometric, endocrine, metabolic and immunological parameters than aged subjects (> 75 years old). Heart rate variability (HRV) has been...

View article titled, Baseline heart rate variability in healthy centenarians: differences compared with aged subjects (&gt;75 years old)

Articles

Use of opposing reflex stimuli and heart rate variability to examine the effects of lipophilic and hydrophilic β-blockers on human cardiac vagal control

Julian C. VAILE, Janine FLETCHER, Muzahim AL-ANI, Hamish F. ROSS, William A. LITTLER, John H. COOTE, Jonathan N. TOWNEND

Clin Sci (Lond) (1999) 97 (5): 585–593.

DOI: https://doi.org/10.1042/cs0970585

Published: 28 September 1999

... whether such an effect is evident in healthy humans, by examining the effects of lipophilic and hydrophilic agents on heart rate variability and cardiac vagal reflexes. A total of 20 healthy volunteers took part in the study. Autonomic studies were performed after 72 h of treatment with placebo, atenolol...

View article titled, Use of opposing reflex stimuli and heart rate variability to examine the effects of lipophilic and hydrophilic β-blockers on human cardiac vagal control

Articles

Comparison between spectral analysis and the phenylephrine method for the assessment of baroreflex sensitivity in chronic heart failure

Roberto COLOMBO, Giorgio MAZZUERO, Gianluca SPINATONDA, Paola LANFRANCHI, Pantaleo GIANNUZZI, Piotr PONIKOWSKI, Andrew J. S. COATS, Giuseppe MINUCO

Clin Sci (Lond) (1999) 97 (4): 503–513.

DOI: https://doi.org/10.1042/cs0970503

Published: 17 September 1999

... and the Medical Research Society © 1999 1999 baroreceptor reflex sensitivity heart failure heart rate variability spectral analysis 503Clinical Science (1999) 97, 503 513 (Printed in Great Britain) Comparison between spectral analysis and the phenylephrine method for the assessment of baroreflex...

View article titled, Comparison between spectral analysis and the phenylephrine method for the assessment of baroreflex sensitivity in chronic heart failure

Articles

Effect of adenosine on heart rate variability in humans

Gerard A. RONGEN, Steven C. BROOKS, Michael J. POLLARD, Shin-ichi ANDO, Hilmi R. DAJANI, Catherine F. NOTARIUS, John S. FLORAS

Clin Sci (Lond) (1999) 96 (6): 597–604.

DOI: https://doi.org/10.1042/cs0960597

Published: 07 May 1999

... in humans that overrides its direct negative chronotropic effect. We tested the hypothesis that adenosine increases heart rate by suppressing parasympathetic and augmenting sympathetic components of heart rate variability. High-frequency ( P H ; 0.15-0.50 Hz) and low-frequency ( P L ; 0.05-0.15 Hz...

View article titled, Effect of adenosine on heart rate variability in humans

Articles

Dissociation between microneurographic and heart rate variability estimates of sympathetic tone in normal subjects and patients with heart failure

Catherine F. NOTARIUS, Gary C. BUTLER, Shin-ichi ANDO, Michael J. POLLARD, Beverley L. SENN, John S. FLORAS

Clin Sci (Lond) (1999) 96 (6): 557–565.

DOI: https://doi.org/10.1042/cs0960557

Published: 28 April 1999

...Catherine F. NOTARIUS; Gary C. BUTLER; Shin-ichi ANDO; Michael J. POLLARD; Beverley L. SENN; John S. FLORAS The concept that spectral analysis of heart rate variability (HRV) can estimate cardiac sympathetic nerve traffic in subjects with both normal and impaired left ventricular systolic function...

View article titled, Dissociation between microneurographic and heart rate variability estimates of sympathetic tone in normal subjects and patients with heart failure

Articles

Autonomic nervous system dysfunction in sclerodermic and primary Raynaud's phenomenon

Paolo PANCERA, Stefano SANSONE, Barbara PRESCIUTTINI, Luciano MONTAGNA, Silvia CERÙ, Claudio LUNARDI, Alessandro LECHI

Clin Sci (Lond) (1998) 96 (1): 49–57.

DOI: https://doi.org/10.1042/cs0960049

Published: 01 January 1999

... the sympathetic (low-frequency) and vagal (high-frequency) components of heart rate variability, in supine and upright positions, in 10 patients with systemic sclerosis, 12 patients with primary Raynaud's phenomenon and 14 controls. We also analysed lung function in order to evaluate a possible link between heart...

View article titled, Autonomic nervous system dysfunction in sclerodermic and primary Raynaud's phenomenon

Articles

Cardiovascular autonomic modulation and activity of carotid baroreceptors at altitude

Luciano BERNARDI, Claudio PASSINO, Giammario SPADACINI, Alessandro CALCIATI, Robert ROBERGS, Richard GREENE, Emilia MARTIGNONI, Inder ANAND, Otto APPENZELLER

Clin Sci (Lond) (1998) 95 (5): 565–573.

DOI: https://doi.org/10.1042/cs0950565

Published: 01 November 1998

... Hypoxia (due to endogenous or atmospheric causes) not only affects ventilation, but also greatly influences autonomic cardiovascular regulation in normal as well as Key words : autonomic nervous system, baroreflex, heart rate variability, high altitude. Abbreviations : HF, high frequency; LF, low...

View article titled, Cardiovascular autonomic modulation and activity of carotid baroreceptors at altitude

Articles

Heart rate and flow velocity variability as determined from umbilical Doppler velocimetry at 10–20 weeks of gestation

Nicolette T. C. URSEM, Piet C. STRUIJK, Wim C. J. HOP, Edward B. CLARK, Bradley B. KELLER, Juriy W. WLADIMIROFF

Clin Sci (Lond) (1998) 95 (5): 539–545.

DOI: https://doi.org/10.1042/cs0950539

Published: 01 November 1998

...Nicolette T. C. URSEM; Piet C. STRUIJK; Wim C. J. HOP; Edward B. CLARK; Bradley B. KELLER; Juriy W. WLADIMIROFF 1. The aim of this study was to define from umbilical artery flow velocity waveforms absolute peak systolic and time-averaged velocity, fetal heart rate, fetal heart rate variability...

View article titled, Heart rate and flow velocity variability as determined from umbilical Doppler velocimetry at 10–20 weeks of gestation

Articles

Human cardiovascular variability, baroreflex and hormonal adaptations to a blood donation

Jacques-Olivier FORTRAT, Olivier NASR, Monique DUVAREILLE, Claude GHARIB

Clin Sci (Lond) (1998) 95 (3): 269–275.

DOI: https://doi.org/10.1042/cs0950269

Published: 01 September 1998

... regulating hormones heart rate variability fractal non-hypotensive haemorrhage Correspondence : Dr J. O. Fortrat. 5 1 1998 20 3 1998 7 5 1998 269Clinical Science (1998) 95, 269 275 (Printed in Great Britain) Human cardiovascular variability, baroreflex and hormonal adaptations...

View article titled, Human cardiovascular variability, baroreflex and hormonal adaptations to a blood donation

Articles

Cardiovascular Autonomic Testing in Adolescents with Type I (Insulin-Dependent) Diabetes Mellitus: An 18-Month Follow-up Study

Andrea Scaramuzza, Fabrizio Salvucci, Stefano Leuzzi, Alberto Radaelli, Giuseppe d'Annunzio, Pietro Fratino, Renata Lorini, Luciano Bernardi

Clin Sci (Lond) (1998) 94 (6): 615–621.

DOI: https://doi.org/10.1042/cs0940615

Published: 01 June 1998

.... The aim of our study was to assess whether cardiovascular parameter abnormalities are already Key words: adolescents, autonomic neuropathy. baroreflex sensitivity, cardiovascular reflexes, heart rate variability, power spectral analysis, Type I diabetes mellitus. Abbreviations: AN, autonomic neuropathy...

View article titled, Cardiovascular Autonomic Testing in Adolescents with Type I (Insulin-Dependent) Diabetes Mellitus: An 18-Month Follow-up Study

Articles

Long- and Short-Term Blood Pressure and Rr-Interval Variability and Psychosomatic Distress in Chronic Fatigue Syndrome

Daniel A. Duprez, Marc L. De Buyzere, Benny Drieghe, Friedl Vanhaverbeke, Youri Taes, Walter Michielsen, Denis L Clement

Clin Sci (Lond) (1998) 94 (1): 57–63.

DOI: https://doi.org/10.1042/cs0940057

Published: 01 January 1998

...: blood pressure. chronic fatigue syndrome. heart rate variability, power rpearal analyus, psvdroxrmaM distress. Abbmubons: BP. blood pressure; U S , chrunK fatigue syndrome, CV, coeffKieot of variation; HF, high frqwncy, LF, low fqwncy. Conarpondencc: Professor D. Duprez. . . 58 D. A. Duprez et al...

View article titled, Long- and Short-Term Blood Pressure and Rr-Interval Variability and Psychosomatic Distress in Chronic Fatigue Syndrome

Articles

Age, Gender and Fractal Scaling in Heart Rate Variability

Kuniaki Otsuka, Germaine Cornelissen, Franz Halberg

Clin Sci (Lond) (1997) 93 (4): 299–308.

DOI: https://doi.org/10.1042/cs0930299

Published: 01 October 1997

...Kuniaki Otsuka; Germaine Cornelissen; Franz Halberg 1. The fractal scaling of heart rate variability, gauged by the correlation dimension (CD), is hypothesized to be characterized by a time structure (chronome), which in health shows differences as a function of gender and age. 2. From 24 h Holter...

View article titled, Age, Gender and Fractal Scaling in Heart Rate Variability

Articles

Age- and Gender-Related Changes in Endothelin and Catecholamine Release, and in Autonomic Balance in Response to Head-Up Tilt

Michel White, Marc Courtemanche, Duncan J. Stewart, Mario Talajic, Ethel Mikes, Peter Cernacek, Pascal Vantrimpont, Diane Leclerc, Lizanne Bussières, Jean L. Rouleau

Clin Sci (Lond) (1997) 93 (4): 309–316.

DOI: https://doi.org/10.1042/cs0930309

Published: 01 October 1997

... volunteers (68 ± 7 years) underwent a 30 min head-up tilt test at 60°. Haemodynamics were measured every 5 min and blood samples for neurohormone measurement were drawn at baseline, 5, 10, 15 and 30 min into the test. Heart rate variability was analysed in 5 min segments at the baseline, and during the test...

View article titled, Age- and Gender-Related Changes in Endothelin and Catecholamine Release, and in Autonomic Balance in Response to Head-Up Tilt

Articles

Complementary and Non-Coincident Increases in Heart Rate Variability and Irregularity during Fetal Development

Lee A. Fleisher, Janet A. Dipietro, Timothy R. B. Johnson, Steven Pincus

Clin Sci (Lond) (1997) 92 (4): 345–349.

DOI: https://doi.org/10.1042/cs0920345

Published: 01 April 1997

... a difference in gender-based development as noted in the separate context of fetal lung maturation. 21 11 1996 28 11 1996 © 1997 The Biochemical Society and the Medical Research Society 1997 complexity electrocardiogram fetus gender heart rate variability Clinical Science (1997...

View article titled, Complementary and Non-Coincident Increases in Heart Rate Variability and Irregularity during Fetal Development

Articles

Modulation of Neurocardiac Function by Oesophageal Stimulation in Humans

Gervais Tougas, Markad Kamath, Geena Watteel, Debbie Fitzpatrick, Ernest L. Fallen, Richard H. Hunt, Adrian R. M. Upton

Clin Sci (Lond) (1997) 92 (2): 167–174.

DOI: https://doi.org/10.1042/cs0920167

Published: 01 February 1997

... on the power spectrum of beat-to-beat heart rate variability in male volunteers. 2. In 14 healthy volunteers, beat-to-beat heart rate variability was compared at rest and during oesophageal stimulation, using either electrical (200 μs, 16 mA, 0.2 Hz) or mechanical (0.5 s, 14 ml, 0.2 Hz) stimuli. The power...

View article titled, Modulation of Neurocardiac Function by Oesophageal Stimulation in Humans

Articles

Reproducibility of Heart Rate Variability Measures in Patients with Chronic Heart Failure

Piotr Ponikowski, Massimo Piepoli, Aham A. Amadi, Tuan Peng Chua, Derek Harrington, Maurizio Volterrani, Roberto Colombo, Giorgio Mazzuero, Amerigo Giordano, Andrew J. S. Coats

Clin Sci (Lond) (1996) 91 (4): 391–398.

DOI: https://doi.org/10.1042/cs0910391

Published: 01 October 1996

...Piotr Ponikowski; Massimo Piepoli; Aham A. Amadi; Tuan Peng Chua; Derek Harrington; Maurizio Volterrani; Roberto Colombo; Giorgio Mazzuero; Amerigo Giordano; Andrew J. S. Coats 1. In patients with chronic heart failure, heart rate variability is reduced with relative preservation of very-low...

View article titled, Reproducibility of Heart Rate Variability Measures in Patients with Chronic Heart Failure

Articles

Poincaré Plot of Heart Rate Variability Allows Quantitative Display of Parasympathetic Nervous Activity in Humans

Peter Walter Kamen, Henry Krum, Andrew Maxwell Tonkin

Clin Sci (Lond) (1996) 91 (2): 201–208.

DOI: https://doi.org/10.1042/cs0910201

Published: 01 August 1996

...Peter Walter Kamen; Henry Krum; Andrew Maxwell Tonkin 1. Time domain summary statistics and frequency domain parameters can be used to measure heart rate variability. More recently, qualitative methods including the Poincaré plot have been used to evaluate heart rate variability. The aim...

View article titled, Poincaré Plot of Heart Rate Variability Allows Quantitative Display of Parasympathetic Nervous Activity in Humans

Articles

Impact of Changes in Respiratory Frequency and Posture on Power Spectral Analysis of Heart Rate and Systolic Blood Pressure Variability in Normal Subjects and Patients with Heart Failure

John E. Sanderson, Leata Y. C. Yeung, Dickens T. K. Yeung, Richard L. C. Kay, Brian Tomlinson, J. A. J. H. Critchley, Kam S. Woo, Luciano Bernardi

Clin Sci (Lond) (1996) 91 (1): 35–43.

DOI: https://doi.org/10.1042/cs0910035

Published: 01 July 1996

.... The low-frequency/high-frequency ratio derived from power spectral analysis of heart rate variability has been proposed as a non-invasive method to assess sympatho-vagal balance. However, the effects of different respiratory rates or posture are rarely accounted for, but may be relevant in patients...

View article titled, Impact of Changes in Respiratory Frequency and Posture on Power Spectral Analysis of Heart Rate and Systolic Blood Pressure Variability in Normal Subjects and Patients with Heart Failure

Articles

Autonomic Control of Skin Microvessels: Assessment by Power Spectrum of Photoplethysmographic Waves

Luciano Bernardi, Alberto Radaelli, Pier Luigi Solda, Andrew J. S. Coats, Martin Reeder, Alessandro Calciati, Christopher S. Garrard, Peter Sleight

Clin Sci (Lond) (1996) 90 (5): 345–355.

DOI: https://doi.org/10.1042/cs0900345

Published: 01 May 1996

... pressure. 16 1 1995 21 1 1996 25 1 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 arterial baroreflexes autonomic nervous system heart rate variability microcirculation postural changes power spectrum skin blood flow Clinical Science (1996) 90...

View article titled, Autonomic Control of Skin Microvessels: Assessment by Power Spectrum of Photoplethysmographic Waves

Articles

Respiratory Sinus Arrhythmia and Central Respiratory Drive in Humans

M. Al-Ani, A. S. Forkins, J. N. Townend, J. H. Coote

Clin Sci (Lond) (1996) 90 (3): 235–241.

DOI: https://doi.org/10.1042/cs0900235

Published: 01 March 1996

...M. Al-Ani; A. S. Forkins; J. N. Townend; J. H. Coote 1. The influence of central inspiratory drive on heart rate variability was investigated in young human subjects using power spectral analysis of R—R intervals. 2. The area of the high-frequency component occurring at the respiratory frequency...

View article titled, Respiratory Sinus Arrhythmia and Central Respiratory Drive in Humans

Articles

Thermoregulation and Heart Rate Variability

Lee A. Fleisher, Steven M. Frank, Daniel I. Sessler, Christi Cheng, Takashi Matsukawa, Carole A. Vannier

Clin Sci (Lond) (1996) 90 (2): 97–103.

DOI: https://doi.org/10.1042/cs0900097

Published: 01 February 1996

...Lee A. Fleisher; Steven M. Frank; Daniel I. Sessler; Christi Cheng; Takashi Matsukawa; Carole A. Vannier 1. Heart rate variability is modulated by multiple control systems, including autonomic and hormonal systems. Long-term variability, i.e. the very low-frequency band of the power spectra, has...

View article titled, Thermoregulation and Heart Rate Variability

Articles

Sympathetic Stimulations by Exercise-Stress Testing and by Dobutamine Infusion Induce Similar Changes in Heart Rate Variability in Patients with Chronic Heart Failure

Massimo Piepoli, Stamatis Adamopoulos, Luciano Bernardi, Peter Sleight, Andrew J. S. Coats

Clin Sci (Lond) (1995) 89 (2): 155–164.

DOI: https://doi.org/10.1042/cs0890155

Published: 01 August 1995

...Massimo Piepoli; Stamatis Adamopoulos; Luciano Bernardi; Peter Sleight; Andrew J. S. Coats 1. Heart rate variability can be used to evaluate autonomic balance, but it is unclear how inotropic therapy may affect the findings. The aim of the study was to assess whether heart rate variability can...

View article titled, Sympathetic Stimulations by Exercise-Stress Testing and by Dobutamine Infusion Induce Similar Changes in Heart Rate Variability in Patients with Chronic Heart Failure

Articles

Physiology and Pathophysiology of Heart Rate and Blood Pressure Variability in Humans: Is Power Spectral Analysis Largely An Index of Baroreflex Gain?

Peter Sleight, Maria Teresa La Rovere, Andrea Mortara, Gianni Pinna, Roberto Maestri, Stefano Leuzzi, Beatrice Bianchini, Luigi Tavazzi, Luciano Bernardi

Clin Sci (Lond) (1995) 88 (1): 103–109.

DOI: https://doi.org/10.1042/cs0880103

Published: 01 January 1995

... nervous system baroreflex sensitivity heart failure heart rate variability Clinical Science (1995) 88, 103409 (Printed in Great Britain) I03 Physiology and pathophysiology of heart rate and blood pressure variability in humans: is power spectral analysis largely an index of baroreflex gain? Peter...

View article titled, Physiology and Pathophysiology of Heart Rate and Blood Pressure Variability in Humans: Is Power Spectral Analysis Largely An Index of Baroreflex Gain?

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