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Articles

Arginine infusion in patients with septic shock increases nitric oxide production without haemodynamic instability

Yvette C. Luiking, Martijn Poeze, Nicolaas E. Deutz

Clin Sci (Lond) (2015) 128 (1): 57–67.

DOI: https://doi.org/10.1042/CS20140343

Published: 29 August 2014

...Yvette C. Luiking; Martijn Poeze; Nicolaas E. Deutz Arginine deficiency in sepsis may impair nitric oxide (NO) production for local perfusion and add to the catabolic state. In contrast, excessive NO production has been related to global haemodynamic instability. Therefore, the aim of the present...

View article titled, Arginine infusion in patients with septic shock increases nitric oxide production without haemodynamic instability

Includes: Supplementary data

Articles

Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure

Tzu-Pin Weng, Tieh-Cheng Fu, Chao-Hung Wang, Chih-Chin Hsu, Jong-Shyan Wang

Clin Sci (Lond) (2014) 127 (10): 589–602.

DOI: https://doi.org/10.1042/CS20130789

Published: 18 July 2014

...Tzu-Pin Weng; Tieh-Cheng Fu; Chao-Hung Wang; Chih-Chin Hsu; Jong-Shyan Wang Lymphocytopenia is associated with an adverse prognosis in heart failure (HF). The present study investigated whether lymphocytopenia results from activated lymphocyte autophagy/apoptosis, which reflects haemodynamic...

View article titled, Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure

Articles

Effects of moderate-intensity aerobic cycling and swim exercise on post-exertional blood pressure in healthy young untrained and triathlon-trained men and women

Robert Lakin, Catherine Notarius, Scott Thomas, Jack Goodman

Clin Sci (Lond) (2013) 125 (12): 543–553.

DOI: https://doi.org/10.1042/CS20120508

Published: 02 August 2013

... described above, with adjustments in swim pace made accordingly. acute aerobic exercise autonomic nervous system blood pressure haemodynamics post-exercise hypotension (PEH) swimming • Current evidence suggests that all forms of regular aerobic exercise are equally effective at lowering...

View article titled, Effects of moderate-intensity aerobic cycling and swim exercise on post-exertional blood pressure in healthy young untrained and triathlon-trained men and women

Articles

Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats

Peter C. Papageorgiou, Erik L. Yeo, Peter H. Backx, John S. Floras

Clin Sci (Lond) (2012) 122 (12): 581–590.

DOI: https://doi.org/10.1042/CS20110517

Published: 05 March 2012

... (mean arterial pressure), SV (stroke volume) and HR. Saline had no haemodynamic effects. β-FXIIa infusion increased its plasma concentration 3-fold in both groups. In adrenally intact rats, β-FXIIa infusion increased MAP by 6% (5±2 mmHg) and TPR by 45% (0.50±0.12 mmHg/ml per min), despite falls in SV...

View article titled, Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats

Includes: Supplementary data

Articles

Haemodynamic, endocrine and renal actions of adrenomedullin 5 in an ovine model of heart failure

Miriam T. Rademaker, Christopher J. Charles, M. Gary Nicholls, A. Mark Richards

Clin Sci (Lond) (2012) 122 (9): 429–437.

DOI: https://doi.org/10.1042/CS20110483

Published: 16 January 2012

... in urine volume (HD 2-fold increment, P <0.05) and urine sodium (2.7-fold increment, P <0.01), potassium (1.7-fold increment, P <0.05) and creatinine (1.4-fold increment, P <0.05) excretion and creatinine clearance (60% increment, P <0.05). In conclusion, AM5 has significant haemodynamic...

View article titled, Haemodynamic, endocrine and renal actions of adrenomedullin 5 in an ovine model of heart failure

Articles

Monitoring of heart failure: comparison of left atrial pressure with intrathoracic impedance and natriuretic peptide measurements in an experimental model of ovine heart failure

Miriam T. Rademaker, Christopher J. Charles, Iain C. Melton, A. Mark Richards, Christopher M. Frampton, Jeff Siou, Fujian Qu, Neal L. Eigler, Dan Gutfinger, Richard W. Troughton

Clin Sci (Lond) (2011) 120 (5): 207–217.

DOI: https://doi.org/10.1042/CS20100388

Published: 19 November 2010

...://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. haemodynamics heart failure implantable monitor intrathoracic impedance left atrial pressure natriuretic peptide HF...

View article titled, Monitoring of heart failure: comparison of left atrial pressure with intrathoracic impedance and natriuretic peptide measurements in an experimental model of ovine heart failure

Articles

Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade

Jasper Truijen, Shyrin C.A.T. Davis, Wim J. Stok, Yu-Sok Kim, David J. van Westerloo, Marcel Levi, Tom van der Poll, Berend E. Westerhof, John M. Karemaker, Johannes J. van Lieshout

Clin Sci (Lond) (2011) 120 (4): 161–167.

DOI: https://doi.org/10.1042/CS20100137

Published: 02 November 2010

... 0.85±0.18 0.92±0.21 1.24±0.28‡‡ − − 1.24±0.42‡‡ PROP 1.05±0.32 1.03±0.12 1.69±0.44*‡ − − 1.47±0.16‡‡ adrenergic β-antagonist autonomic nervous system baroreflex haemodynamics psychological stress Physiological adaptation to a potentially threatening situation...

View article titled, Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade

Articles

Urocortin 2 combined with angiotensin-converting enzyme inhibition in experimental heart failure

Miriam T. Rademaker, Christopher J. Charles, M. Gary Nicholls, A. Mark Richards

Clin Sci (Lond) (2008) 114 (10): 635–642.

DOI: https://doi.org/10.1042/CS20070364

Published: 14 April 2008

... in haemodynamics, hormonal profile and renal function than achieved by captopril alone. These results indicate that dual treatment with these two agents is beneficial. Correspondence: Dr Miriam T. Rademaker (email miriam.rademaker@chmeds.ac.nz ). 15 10 2007 26 11 2007 5 12 2007 5 12...

View article titled, Urocortin 2 combined with angiotensin-converting enzyme inhibition in experimental heart failure

Articles

Reduced body mass index is associated with increased angiotensin II in young women with postural tachycardia syndrome

Julian M. Stewart, Indu Taneja, Marvin S. Medow

Clin Sci (Lond) (2007) 113 (11): 449–457.

DOI: https://doi.org/10.1042/CS20070104

Published: 01 November 2007

...Julian M. Stewart; Indu Taneja; Marvin S. Medow Altered peripheral haemodynamics, decreased cardiac output, decreased blood volume and increased AngII (angiotensin II) have been reported in POTS (postural tachycardia syndrome). Recent findings indicate that BMI (body mass index) may be reduced...

View article titled, Reduced body mass index is associated with increased angiotensin II in young women with postural tachycardia syndrome

Articles

Management of initial orthostatic hypotension: lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squatting

C. T. Paul Krediet, Ingeborg K. Go-Schön, Yu-Sok Kim, Mark Linzer, Johannes J. Van Lieshout, Wouter Wieling

Clin Sci (Lond) (2007) 113 (10): 401–407.

DOI: https://doi.org/10.1042/CS20070064

Published: 12 October 2007

... transient BP decrease [e.g. >40 mmHg SBP (systolic BP)] [ 2 ]. In particular, standing up from squatting has been recognized as an acute haemodynamic stressor [ 3 , 4 ] which can provoke these complaints. As with vasovagal syncope, for which, according to current guidelines, history taking rather...

View article titled, Management of initial orthostatic hypotension: lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squatting

Articles

Urocortin 1 modulates the neurohumoral response to acute nitroprusside-induced hypotension in sheep

Christopher J. Charles, Miriam T. Rademaker, A. Mark Richards

Clin Sci (Lond) (2007) 112 (9): 485–491.

DOI: https://doi.org/10.1042/CS20060303

Published: 02 April 2007

...Christopher J. Charles; Miriam T. Rademaker; A. Mark Richards In addition to haemodynamic actions, Ucn1 (urocortin 1) has been reported to affect a number of hormonal systems; however, it remains unclear whether Ucn1 modulates circulating hormones under physiological conditions. Accordingly...

View article titled, Urocortin 1 modulates the neurohumoral response to acute nitroprusside-induced hypotension in sheep

Articles

Administration of brain natriuretic peptide improves cardiac function following operations using extracorporeal circulation in an animal model

Dorothee H. L. Bail, Volker Steger, Uli Heinzelmann, Sandra Schiller, Anita I. Geim, Benjamin Brüllmann, Gerhard Ziemer

Clin Sci (Lond) (2007) 112 (5): 315–324.

DOI: https://doi.org/10.1042/CS20060136

Published: 01 February 2007

.... (intravenous) bolus at 0.3 μg·kg −1 of body weight·min −1 , followed by an infusion at a rate of 0.015 μg·kg −1 of body weight·min −1 for 60 min. The animals in the control group ( n =10) received a saline solution instead of BNP. Haemodynamic and clinical chemistry parameters as well as the amount...

View article titled, Administration of brain natriuretic peptide improves cardiac function following operations using extracorporeal circulation in an animal model

Articles

Influence of central inhibition of sympathetic nervous activity on myocardial metabolism in chronic heart failure: acute effects of the imidazoline I 1 -receptor agonist moxonidine

Reza Mobini, Michael Fu, Per-Anders Jansson, Claes-Håkan Bergh, Margareta Scharin Täng, Finn Waagstein, Bert Andersson

Clin Sci (Lond) (2006) 110 (3): 329–336.

DOI: https://doi.org/10.1042/CS20050037

Published: 10 February 2006

.... In the present study, we studied the acute effects of the imidazoline-receptor agonist moxonidine on haemodynamics, NA (noradrenaline) kinetics and myocardial metabolism. Fifteen patients with CHF (chronic heart failure) were randomized to a single dose of 0.6 mg of sustained-release moxonidine or matching...

View article titled, Influence of central inhibition of sympathetic nervous activity on myocardial metabolism in chronic heart failure: acute effects of the imidazoline I 1 -receptor agonist moxonidine

Articles

Water drinking improves orthostatic tolerance in patients with posturally related syncope

Victoria E. Claydon, Christoph Schroeder, Lucy J. Norcliffe, Jens Jordan, Roger Hainsworth

Clin Sci (Lond) (2006) 110 (3): 343–352.

DOI: https://doi.org/10.1042/CS20050279

Published: 10 February 2006

... Society 2006 head-up tilting haemodynamics orthostatic tolerance posturally related syncope water Syncope is a common medical problem, responsible for 0.77% of hospital admissions in the United States [ 1 ] and between 0.9–1.2% of hospital admissions in Europe [ 2 ]. It does not have...

View article titled, Water drinking improves orthostatic tolerance in patients with posturally related syncope

Articles

Haemodynamically significant plaque formation and regional endothelial dysfunction in cholesterol-fed ApoE −/− mice

Maria E. JOHANSSON, Ulrika HÄGG, Johannes WIKSTRÖM, Anna WICKMAN, Göran BERGSTRÖM, Li-ming GAN

Clin Sci (Lond) (2005) 108 (6): 531–538.

DOI: https://doi.org/10.1042/CS20040322

Published: 24 May 2005

... significantly alters aortic root haemodynamics. This phenomenon is associated with impaired NO-dependent vasodilation in vessel segments known to be prone to atherosclerosis. 1 These authors contributed equally to this work. Correspondence: Dr Li-ming Gan, Department of Physiology, Institute...

View article titled, Haemodynamically significant plaque formation and regional endothelial dysfunction in cholesterol-fed ApoE −/− mice

Articles

Effect of eprosartan on catecholamines and peripheral haemodynamics in subjects with insulin-induced hypoglycaemia

Marina CHRISTENSEN, Hans IBSEN, René WORCK

Clin Sci (Lond) (2005) 108 (2): 113–119.

DOI: https://doi.org/10.1042/CS20040094

Published: 21 January 2005

... =0.57). In conclusion, EPRO did not significantly inhibit sympathetic reactivity compared with placebo; however, it blunted the haemodynamic responses elicited by the sympatho-adrenal stimulation which only tended to be attenuated by this drug. 25 3 2004 1 9 2004 22 9 2004 22 9 2004...

View article titled, Effect of eprosartan on catecholamines and peripheral haemodynamics in subjects with insulin-induced hypoglycaemia

Articles

Voluntary physical exercise-induced vascular effects in spontaneously hypertensive rats

Ulrika HÄGG, Irene ANDERSSON, Andrew S. NAYLOR, Julia GRÖNROS, Ingibjörg H. JONSDOTTIR, Göran BERGSTRÖM, Li-ming GAN

Clin Sci (Lond) (2004) 107 (6): 571–581.

DOI: https://doi.org/10.1042/CS20040171

Published: 24 November 2004

... of age were used in the study, since animals of this age are considered to have established hypertension. Using this voluntary exercise model, effects of exercise on central haemodynamics in adult SHR have been studied extensively [ 13 , 14 ]. It has also been shown that plasma level of nitrate...

View article titled, Voluntary physical exercise-induced vascular effects in spontaneously hypertensive rats

Articles

Significance of the endothelin ET A receptor in the haemodynamic and inotropic effects of endothelin-1 in rats

Martin E. BEYER, Tobias HÖVELBORN, Ursula DELABAR, Hans Martin HOFFMEISTER

Clin Sci (Lond) (2004) 107 (5): 467–475.

DOI: https://doi.org/10.1042/CS20030352

Published: 26 October 2004

.... In anaesthetized open-chest rats the haemodynamic and inotropic effects of ET A receptor stimulation were studied by monitoring responses evoked by ET-1 (1 nmol/kg of body weight) after ET B receptor blockade with BQ 788 (0.5 μmol/kg of body weight); these responses were compared with saline controls (after ET B...

View article titled, Significance of the endothelin ET A receptor in the haemodynamic and inotropic effects of endothelin-1 in rats

Articles

Coupling of metabolism and cardiovascular responses

Keith N. FRAYN, Jean-Luc ARDILOUZE, Barbara A. FIELDING, Fredrik KARPE

Clin Sci (Lond) (2004) 106 (5): 547–548.

DOI: https://doi.org/10.1042/CS20030409

Published: 01 May 2004

... Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford OX3 7LJ, U.K. We read with interest the paper by Fugmann et al. [1], in a previous issue of Clinical Science, showing the close link between metabolic changes, mimicking those of the postprandial state, and haemodynamic...

View article titled, Coupling of metabolism and cardiovascular responses

Articles

Central and peripheral haemodynamic effects of hyperglycaemia, hyperinsulinaemia, hyperlipidaemia or a mixed meal

Andreas FUGMANN, Jonas MILLGÅRD, Mahziar SARABI, Christian BERNE, Lars LIND

Clin Sci (Lond) (2003) 105 (6): 715–721.

DOI: https://doi.org/10.1042/CS20030036

Published: 01 December 2003

...Andreas FUGMANN; Jonas MILLGÅRD; Mahziar SARABI; Christian BERNE; Lars LIND The aim of the present study was to evaluate the haemodynamic changes during hyperinsulinaemia, hyperglycaemia or hypertriglyceridaemia in relation to those following a mixed meal. Ten subjects were subjected...

View article titled, Central and peripheral haemodynamic effects of hyperglycaemia, hyperinsulinaemia, hyperlipidaemia or a mixed meal

Articles

Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans

Mitsunobu ENOMOTO, Noritoshi NAGAYA, Masaaki UEMATSU, Hiroyuki OKUMURA, Eiichiroh NAKAGAWA, Fumiaki ONO, Hiroshi HOSODA, Hideo OYA, Masayasu KOJIMA, Katsuo KANMATSUSE, Kenji KANGAWA

Clin Sci (Lond) (2003) 105 (4): 431–435.

DOI: https://doi.org/10.1042/CS20030184

Published: 01 October 2003

... min after ghrelin administration. These haemodynamic and hormonal changes were still apparent 60 min after ghrelin injection. In conclusion, subcutaneous administration of ghrelin dose-dependently induced relatively specific GH release and enhanced cardiac performance in humans. cardiac function...

View article titled, Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans

Articles

Natriuretic peptides maintain sodium homoeostasis during chronic volume loading post-myocardial infarction in sheep

Christopher J. CHARLES, John M. ELLIOTT, M. Gary NICHOLLS, Miriam T. RADEMAKER, A. Mark RICHARDS

Clin Sci (Lond) (2003) 104 (4): 429–436.

DOI: https://doi.org/10.1042/cs1040429

Published: 20 March 2003

... (all P <0.05) were higher in the MI group compared with normal control sheep. There were no differences in haemodynamics, body mass or renin–aldosterone levels between groups. This study provides evidence that natriuretic peptides play a pivotal role in preserving volume/electrolyte balance...

View article titled, Natriuretic peptides maintain sodium homoeostasis during chronic volume loading post-myocardial infarction in sheep

Articles

High-dose heparin fails to improve acute lung injury following smoke inhalation in sheep

Kazunori MURAKAMI, Perenlei ENKHBAATAR, Katsumi SHIMODA, Akio MIZUTANI, Robert A. COX, Frank C. SCHMALSTIEG, Jeffrey M. JODOIN, Hal K. HAWKINS, Lillian D. TRABER, Daniel L. TRABER

Clin Sci (Lond) (2003) 104 (4): 349–356.

DOI: https://doi.org/10.1042/cs1040349

Published: 06 March 2003

... 77555-0833, U.S.A. (e-mail dltraber@utmb.edu ). 26 9 2002 25 10 2002 3 1 2003 The Biochemical Society and the Medical Research Society © 2003 2003 anticoagulant haemodynamics infection/inflammation Pseudomonas aeruginosa septic shock thrombosis 349Clinical Science...

View article titled, High-dose heparin fails to improve acute lung injury following smoke inhalation in sheep

Articles

Cardiovascular effects and cardiopulmonary plasma gradients following intravenous infusion of neuropeptide Y in humans: negative dromotropic effect on atrioventricular node conduction

Bengt ULLMAN, John PERNOW, Jan M. LUNDBERG, Hans ÅSTRÖM, Lennart BERGFELDT

Clin Sci (Lond) (2002) 103 (6): 535–542.

DOI: https://doi.org/10.1042/cs1030535

Published: 30 October 2002

... is greatly elevated in patients with congestive heart failure, but the clinical relevance of this finding is unclear. Central haemodynamic effects, cardiac conduction system electrophysiology and coronary sinus blood flow were therefore studied in two sets of experiments, each carried out on seven healthy...

View article titled, Cardiovascular effects and cardiopulmonary plasma gradients following intravenous infusion of neuropeptide Y in humans: negative dromotropic effect on atrioventricular node conduction

Articles

Arterial waves in humans during peripheral vascular surgery

Ashraf W. KHIR, Michael Y. HENEIN, Tat KOH, Saroj K. DAS, Kim H. PARKER, Derek G. GIBSON

Clin Sci (Lond) (2001) 101 (6): 749–757.

DOI: https://doi.org/10.1042/cs1010749

Published: 21 November 2001

... haemodynamics reflected waves wave intensity. 749Clinical Science (2001) 101, 749 757 (Printed in Great Britain) Arterial waves in humans during peripheral vascular surgery Ashraf W. KHIR*, Michael Y. HENEIN , Tat KOH , Saroj K. DAS , Kim H. PARKER* and Derek G. GIBSON *Physiological Flow Study Group...

View article titled, Arterial waves in humans during peripheral vascular surgery

Articles

Cytokine up-regulation in ischaemic/reperfused lungs perfused with University of Wisconsin solution and normal saline

Chi-Huei CHIANG, Cheng-Ping YU, Chin-Pyng WU, Horng-Chin YAN, Wann-Cherng PERNG

Clin Sci (Lond) (2001) 101 (3): 285–294.

DOI: https://doi.org/10.1042/cs1010285

Published: 15 August 2001

.... Haemodynamics, lung weight gain (LWG), capillary filtration coefficient ( K fc ), tissue pathology, the concentrations of cytokines in the perfusate, and mRNAs for the various cytokines in the lung tissues were measured. I/R induced a permeability type of pulmonary oedema, as reflected by increases in LWG and K...

View article titled, Cytokine up-regulation in ischaemic/reperfused lungs perfused with University of Wisconsin solution and normal saline

Articles

Dexamethasone and pentastarch produce additive attenuation of ischaemia/reperfusion lung injury

Chi-Huei CHIANG, Chin-Pyng WU, Wann-Cherng PERNG, Horng-Chin YAN, Cheng-Ping YU

Clin Sci (Lond) (2000) 99 (5): 413–419.

DOI: https://doi.org/10.1042/cs0990413

Published: 27 October 2000

... in an isolated rat lung model, lungs were reperfused for 60 min in a closed circulating system with one of the following solutions: (1) NS (0.9% normal saline), (2) NS+Dex (dexamethasone), (3) NS+Penta (pentastarch), or (4) NS+Penta+Dex. Haemodynamic changes, lung weight gain (LWG), capillary filtration...

View article titled, Dexamethasone and pentastarch produce additive attenuation of ischaemia/reperfusion lung injury

Articles

Myocardial infarction with and without reperfusion in sheep: early cardiac and neurohumoral changes

Christopher J. CHARLES, John M. ELLIOTT, M. Gary NICHOLLS, Miriam T. RADEMAKER, Mark RICHARDS

Clin Sci (Lond) (2000) 98 (6): 703–711.

DOI: https://doi.org/10.1042/cs0980703

Published: 10 May 2000

... pressures ( P < 0.05), plasma brain natriuretic peptide levels ( P < 0.05) and adrenaline levels ( P < 0.05). Rises seen in plasma endothelin levels in sham controls were blunted in the coil group ( P < 0.001). Haemodynamic changes were less marked in the balloon group. In conclusion...

View article titled, Myocardial infarction with and without reperfusion in sheep: early cardiac and neurohumoral changes

Articles

Internal carotid artery haemodynamics in women with polycystic ovaries

K. LAKHANI, N. CONSTANTINOVICI, W. M. PURCELL, R. FERNANDO, P. HARDIMAN

Clin Sci (Lond) (2000) 98 (6): 661–665.

DOI: https://doi.org/10.1042/cs0980661

Published: 08 May 2000

... mechanisms must be operating in these women. Haemodynamic changes have been demonstrated in the pelvic vessels and aorta in this syndrome, but there have been no studies of the cerebral circulation. Since insulin resistance is a central feature of PCOS, it is of interest that cerebral blood flow may...

View article titled, Internal carotid artery haemodynamics in women with polycystic ovaries

Articles

Influences of carvedilol treatment on the effects of acetylcholine on regional haemodynamics in the spontaneously hypertensive rat

Sven-Olof GRANSTAM, Bengt FELLSTRÖM, Lars LIND

Clin Sci (Lond) (1998) 95 (3): 303–309.

DOI: https://doi.org/10.1042/cs0950303

Published: 01 September 1998

... accordingly. Correspondence : Dr Sven-Olof Granstam. 5 1 1998 18 3 1998 14 4 1998 The Biochemical Society and the Medical Research Society © 1998 1998 acetylcholine blood flow carvedilol haemodynamics hypertension spontaneously hypertensive rat 303Clinical Science...

View article titled, Influences of carvedilol treatment on the effects of acetylcholine on regional haemodynamics in the spontaneously hypertensive rat

Articles

Subjects with obstructive pulmonary disease tend to be chronically vasodilated

Edoardo CASIGLIA, Lucia PAVAN, Luca MARCATO, Marco LEOPARDI, Alessandra PIZZIOL, Paolo SALVADOR, Renzo ZUIN, Achille C. PESSINA

Clin Sci (Lond) (1998) 95 (3): 287–294.

DOI: https://doi.org/10.1042/cs0950287

Published: 01 September 1998

... = 0.02). Minimal resistance was significantly lower in obstructed than in non-obstructed subjects. Both basal and minimal resistance progressively decreased, although insignificantly, with worsening bronchial obstruction. P a c o 2 did not correlate with any haemodynamic parameter. Borg index correlated...

View article titled, Subjects with obstructive pulmonary disease tend to be chronically vasodilated

Articles

Effect of Long-Term Octreotide and Isosorbide Dinitrate on Haemodynamics in Rats with Portal Vein Stenosis

Han-Chieh Lin, Yi-Tsau Huang, Yuh-Ren Cheng, Ming-Chih Hou, Fa-Yauh Lee, Full-Young Chang, Yang-Te Tsai, Shou-Dong Lee

Clin Sci (Lond) (1998) 94 (6): 645–650.

DOI: https://doi.org/10.1042/cs0940645

Published: 01 June 1998

... hypertension, the reduction of portal pressure was enhanced when nitrovasodilators were combined with propranolol or vasopressin. The present study was undertaken to evaluate the effect of long-term administration of octreotide and isosorbide dinitrate on haemodynamics in rats with portal vein stenosis. 2...

View article titled, Effect of Long-Term Octreotide and Isosorbide Dinitrate on Haemodynamics in Rats with Portal Vein Stenosis

Articles

Haemodynamic Responses in Young and Elderly, Healthy Subjects during Ambient and Warm Head-up Tilt

Michael Lye, Tom Walley

Clin Sci (Lond) (1998) 94 (5): 493–498.

DOI: https://doi.org/10.1042/cs0940493

Published: 01 May 1998

... contribute to nocturnal postural hypotension in the elderly. We therefore studied haemodynamic responses to head-up tilt in healthy elderly and young subjects, with and without passive heating induced by covering with blankets. 2. Nine young (28.7 ± 1.5 years; mean ± S.E.M.) and nine elderly (71.9 ± 1.8...

View article titled, Haemodynamic Responses in Young and Elderly, Healthy Subjects during Ambient and Warm Head-up Tilt

Articles

Effect of Narcotic Agents and of Bleeding on Systemic and Renal Haemodynamics in Healthy and CCl 4 -treated Cirrhotic Rats

G. Van Roey, P. Lijnen, R. Verbesselt, A. Verbruggen, J. Fevery

Clin Sci (Lond) (1997) 93 (6): 549–556.

DOI: https://doi.org/10.1042/cs0930549

Published: 01 December 1997

...G. Van Roey; P. Lijnen; R. Verbesselt; A. Verbruggen; J. Fevery 1. The haemodynamic effects of different narcotic agents have been tested in healthy rats and in rats with cirrhosis. 2. Pentobarbital suppresses the sympathetic nervous system. Susceptibility to ketamine is unpredictable, leading...

View article titled, Effect of Narcotic Agents and of Bleeding on Systemic and Renal Haemodynamics in Healthy and CCl 4 -treated Cirrhotic Rats

Articles

Comparative Bioactivity of Atrial and Brain Natriuretic Peptides in An Ovine Model of Heart Failure

Miriam Tessa Rademaker, Christopher John Charles, Eric Arnold Espiner, Christopher Miles Frampton, Michael Gary Nicholls, Arthur Mark Richards

Clin Sci (Lond) (1997) 92 (2): 159–165.

DOI: https://doi.org/10.1042/cs0920159

Published: 01 February 1997

... examined the effects of brain natriuretic peptide (BNP), none have directly compared the bioactivity of similar doses of ANP and BNP under standard conditions of impaired cardiac function. We compared the hormonal, haemodynamic and renal effects of 3 h infusions of ANP, BNP and a vehicle control in eight...

View article titled, Comparative Bioactivity of Atrial and Brain Natriuretic Peptides in An Ovine Model of Heart Failure

Articles

Neutral Endopeptidase Inhibition: Augmented Atrial and Brain Natriuretic Peptide, Haemodynamic and Natriuretic Responses in Ovine Heart Failure

Miriam Tessa Rademaker, Christopher John Charles, Eric Arnold Espiner, Michael Gary Nicholls, Arthur Mark Richards, Teddy Kosoglou

Clin Sci (Lond) (1996) 91 (3): 283–291.

DOI: https://doi.org/10.1042/cs0910283

Published: 01 September 1996

... and brain natriuretic peptide, together with the effects on other vasoactive hormones, haemodynamics and renal indices, to a neutral endopeptidase inhibitor, SCH32615, and a vehicle control in eight conscious sheep before and during pacing-induced heart failure. 2. In normal animals, SCH32615 significantly...

View article titled, Neutral Endopeptidase Inhibition: Augmented Atrial and Brain Natriuretic Peptide, Haemodynamic and Natriuretic Responses in Ovine Heart Failure

Articles

Non-Invasive Measurement of Cardiac Oxygenation and Haemodynamics during Transient Episodes of Coronary Artery Occlusion and Reperfusion in the Pig

M. S. Thorniley, A. Lahiri, B. Glenville, C. Shurey, G. Baker, U. Ravel, J. Crawley, C. J. Green

Clin Sci (Lond) (1996) 91 (1): 51–58.

DOI: https://doi.org/10.1042/cs0910051

Published: 01 July 1996

...M. S. Thorniley; A. Lahiri; B. Glenville; C. Shurey; G. Baker; U. Ravel; J. Crawley; C. J. Green 1. The non-invasive method of near-infrared spectroscopy was used to measure myocardial oxygenation and haemodynamics in response to left anterior descending coronary artery occlusion in a porcine model...

View article titled, Non-Invasive Measurement of Cardiac Oxygenation and Haemodynamics during Transient Episodes of Coronary Artery Occlusion and Reperfusion in the Pig

Articles

Peripheral Microvascular Function in Human Heart Failure

Ian R. Mahy, John E. Tooke

Clin Sci (Lond) (1995) 88 (5): 501–508.

DOI: https://doi.org/10.1042/cs0880501

Published: 01 May 1995

...Ian R. Mahy; John E. Tooke © 1995 The Biochemical Society and the Medical Research Society 1995 autoregulation capillary endothelium haemodynamics heart failure microcirculation oedema Clinical Science (1995) 88, 501-508 (Printed in Great Britain) 50 I Editorial Review Peripheral...

View article titled, Peripheral Microvascular Function in Human Heart Failure

Articles

Haemodynamic and Hormonal Responses to Cardiac Pacing in Humans: Influence of Different Stimulation Sequences and Rates

Hans Berglund, Anders Edlund, Elvar Theodorsson, Hans Vallin

Clin Sci (Lond) (1995) 88 (2): 165–172.

DOI: https://doi.org/10.1042/cs0880165

Published: 01 February 1995

...Hans Berglund; Anders Edlund; Elvar Theodorsson; Hans Vallin 1. To examine the effects of rate and pressure on release of vasoactive hormones, 10 healthy subjects were examined. 2. A standardized pacing protocol was used to achieve different haemodynamic responses at two predetermined heart rates...

View article titled, Haemodynamic and Hormonal Responses to Cardiac Pacing in Humans: Influence of Different Stimulation Sequences and Rates

Articles

Haemodynamic Effects of Continuous Positive Airway Pressure in Humans with Normal and Impaired Left Ventricular Function

Alberto De Hoyos, Peter P. Liu, Dean C. Benard, T. Douglas Bradley

Clin Sci (Lond) (1995) 88 (2): 173–178.

DOI: https://doi.org/10.1042/cs0880173

Published: 01 February 1995

... filling pressures. 19 8 1994 19 9 1994 © 1995 The Biochemical Society and the Medical Research Society 1995 congestive heart failure continuous positive airway pressure haemodynamics Clinical Science (1995) 88, 173-178 (Printed in Great Britain) I73 Haemodynamic effects...

View article titled, Haemodynamic Effects of Continuous Positive Airway Pressure in Humans with Normal and Impaired Left Ventricular Function

Articles

Effect of Head-Down Tilt on Cardiovascular Control in Healthy Subjects: A Spectral Analytic Approach

F. Weise, G. M. London, A. P. Guerin, B. M. Pannier, J.-L. Elghozi

Clin Sci (Lond) (1995) 88 (1): 87–93.

DOI: https://doi.org/10.1042/cs0880087

Published: 01 January 1995

... pressure cardiopulmonary receptors haemodynamics head-down tilt heart rate spectral analysis transfer function analysis Clinical Science (1995) 88, 87-93 (Printed in Great Britain) 87 Effect of headdown tilt on cardiovascular control in healthy subjects: a spectral analytic approach F. WEISE, G. M...

View article titled, Effect of Head-Down Tilt on Cardiovascular Control in Healthy Subjects: A Spectral Analytic Approach

Articles

Exercise Haemodynamics in the Normotensive and the Hypertensive Subject

Paolo Palatini

Clin Sci (Lond) (1994) 87 (3): 275–287.

DOI: https://doi.org/10.1042/cs0870275

Published: 01 September 1994

...Paolo Palatini © 1994 The Biochemical Society and the Medical Research Society 1994 blood pressure cardiac performance echocardiography exercise haemodynamics hypertension left ventricle sport Clinical Science (1994) 87, 275-287 (Printed i n G r e a t Britain) Editorial Review...

View article titled, Exercise Haemodynamics in the Normotensive and the Hypertensive Subject

Articles

l-Arginine Infusion Decreases Peripheral Arterial Resistance and Inhibits Platelet Aggregation in Healthy Subjects

S. M. Bode-Böger, R. H. Böger, A. Creutzig, D. Tsikas, F.-M. Gutzki, K. Alexander, J. C. Frölich

Clin Sci (Lond) (1994) 87 (3): 303–310.

DOI: https://doi.org/10.1042/cs0870303

Published: 01 September 1994

... the effects of an intravenous infusion of L-arginine (30 g, 30 min) compared with placebo on blood pressure, heart rate and peripheral haemodynamics in ten healthy male subjects. Cyclic GMP, NO − 2 and NO − 3 were determined in plasma and urine to assess NO production in vivo by a new, highly specific...

View article titled, l-Arginine Infusion Decreases Peripheral Arterial Resistance and Inhibits Platelet Aggregation in Healthy Subjects

Articles

Influence of 1-Desamino-8-d-Vasopressin on Endogenous Fibrinolysis, Haemodynamics and Liver Blood Flow in Healthy Subjects

J. Burggraaf, H. C. Schoemaker, J. M. Kroon, L. Huisman, C. Kluft, A. F. Cohen

Clin Sci (Lond) (1994) 86 (5): 497–503.

DOI: https://doi.org/10.1042/cs0860497

Published: 01 May 1994

.... However, the possibility that 1-desamino-8-d-vasopressin influences liver blood flow, which is a major determinant of tissue-type plasminogen activator clearance, cannot be ruled out. 2. The influence of 1-desamino-8-d-vasopressin on haemodynamics, liver blood flow and fibrinolytic parameters...

View article titled, Influence of 1-Desamino-8-d-Vasopressin on Endogenous Fibrinolysis, Haemodynamics and Liver Blood Flow in Healthy Subjects

Articles

Haemodynamks of Recovery after Strenuous Exercise in Physically Trained Hypertensive and Normotensive Subjects

Edoardo Casiglia, Paolo Palatini, Stefano Bongiovi, Luca Mario, Giovanna Colangeli, Giuliana Ginocchio, Achille C. Pessina

Clin Sci (Lond) (1994) 86 (1): 27–34.

DOI: https://doi.org/10.1042/cs0860027

Published: 01 January 1994

... resistance were also similar in the two groups. 3. In conclusion, after long-lasting strenuous leg exercise central and peripheral haemodynamics vary to the same degree in hypertensive and normotensive trained subjects. Peripheral haemodynamics (similar in the leg and the arm in both groups) closely reflect...

View article titled, Haemodynamks of Recovery after Strenuous Exercise in Physically Trained Hypertensive and Normotensive Subjects

Articles

Cardiovascular and Sympatho-Adrenal Responses to Mental Stress in Primary Hypertension

Madeleine Lindqvist, Thomas Kahan, Anders Melcher, Paul Hjemdahl

Clin Sci (Lond) (1993) 85 (4): 401–409.

DOI: https://doi.org/10.1042/cs0850401

Published: 01 October 1993

... 1993 The Biochemical Society and the Medical Research Society 1993 catecholamines haemodynamics hypertension neuropeptide Y psychological stress vascular resistance Clinical Science (1993) 85, 40149 (Printed in Great Britain) Cardiovascular and sympathdrenal responses to mental stress...

View article titled, Cardiovascular and Sympatho-Adrenal Responses to Mental Stress in Primary Hypertension

Articles

Systemic and splanchnic haemodynamic effects of pentifylline in rats with portal hypertension

M. Dagenais, G. Pomier-Layrargues, B. Rocheleau, L. Giroux, P.-M. Huet

Clin Sci (Lond) (1992) 83 (1): 41–45.

DOI: https://doi.org/10.1042/cs0830041

Published: 01 July 1992

...M. Dagenais; G. Pomier-Layrargues; B. Rocheleau; L. Giroux; P.-M. Huet 1. The systemic and splanchnic haemodynamic effects of pentifylline (40 mg/kg body weight intravenously) were assessed in rats with portal hypertension associated either with CCl 4 -induced cirrhosis ( n = 13) or portal vein...

View article titled, Systemic and splanchnic haemodynamic effects of pentifylline in rats with portal hypertension

Articles

Renal, haemodynamic and hormonal interactions between atrial natriuretic factor and arginine vasopressin in patients with congestive heart failure

Motoyuki Nakamura, Hiroaki Yoshida, Tsutomu Funakoshi, Naoshi Arakawa, Katsuhiko Hiramori

Clin Sci (Lond) (1992) 82 (4): 363–368.

DOI: https://doi.org/10.1042/cs0820363

Published: 01 April 1992

... in congestive heart failure. Compared with the infusion of arginine vasopressin alone, atrial natriuretic factor co-infusion enhanced both the urine flow rate and the sodium excretion rate (both P < 0.05) without significant haemodynamic and hormonal effects. 3. Systematic blood pressure was elevated...

View article titled, Renal, haemodynamic and hormonal interactions between atrial natriuretic factor and arginine vasopressin in patients with congestive heart failure

Articles

Effects of the Baroreceptor Reflex System on Atrial Natriuretic Factor Secretion during Volume Expansion in Dogs

K. Kohara, A. Otsuka, H. Mikami, K. Katahira, T. Tsunetoshi, T. Ogihara

Clin Sci (Lond) (1989) 77 (1): 29–34.

DOI: https://doi.org/10.1042/cs0770029

Published: 01 July 1989

... reflex haemodynamics sympathetic nervous system volume expansion Clinical Science (1989) 77,29-34 29 Effects of the baroreceptor reflex system on atrial natriuretic factor secretion during volume expansion in dogs K. KOHARA, A. OTSUKA, H. MIKAMI, K. KATAHIRA, T. TSUNETOSHI AND T. OGIHARA Department...

View article titled, Effects of the Baroreceptor Reflex System on Atrial Natriuretic Factor Secretion during Volume Expansion in Dogs

Articles

Haemodynamic effects of physiological concentrations of circulating noradrenaline in man

Peter C. Chang, Eugene Kriek, Jacques A. Van Der Krogt, Gerard-Jan Blauw, Peter Van Brummelen

Clin Sci (Lond) (1988) 75 (5): 469–475.

DOI: https://doi.org/10.1042/cs0750469

Published: 01 November 1988

...Peter C. Chang; Eugene Kriek; Jacques A. Van Der Krogt; Gerard-Jan Blauw; Peter Van Brummelen 1. To define the role of circulating noradrenaline in cardiovascular regulation, threshold concentrations for haemodynamic effects were determined in arterial and venous plasma of eight healthy volunteers...

View article titled, Haemodynamic effects of physiological concentrations of circulating noradrenaline in man

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