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Keywords: growth hormone
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Clin Sci (Lond) (2003) 105 (6): 691–698.
Published: 01 December 2003
... for 18 h and then received intravenous infusions of saline or parenteral nutrition (PN) with or without glutamine for 6 h. In animals receiving PN, parenteral injections of growth hormone (GH) or saline vehicle were also administered. Fractional rate of liver total protein synthesis was elevated...
Clin Sci (Lond) (2003) 105 (4): 431–435.
Published: 01 October 2003
...Mitsunobu ENOMOTO; Noritoshi NAGAYA; Masaaki UEMATSU; Hiroyuki OKUMURA; Eiichiroh NAKAGAWA; Fumiaki ONO; Hiroshi HOSODA; Hideo OYA; Masayasu KOJIMA; Katsuo KANMATSUSE; Kenji KANGAWA Ghrelin is a novel GH (growth hormone)-releasing peptide isolated from the stomach. The cardiovascular and hormonal...
Clin Sci (Lond) (2002) 103 (3): 325–328.
Published: 15 August 2002
...Eiichiro NAKAGAWA; Noritoshi NAGAYA; Hiroyuki OKUMURA; Mitsunobu ENOMOTO; Hideo OYA; Fumiaki ONO; Hiroshi HOSODA; Masayasu KOJIMA; Kenji KANGAWA Ghrelin is a novel growth hormone (GH)-releasing peptide, isolated from the stomach, which may also cause a positive energy balance by stimulating food...
Clin Sci (Lond) (2002) 102 (4): 457–464.
Published: 18 March 2002
...Jonas NYGREN; Anders THORELL; Kerstin BRISMAR; Pia ESSÉN; Jan WERNERMAN; Margaret A. MCNURLAN; Peter J. GARLICK; Olle LJUNGQVIST The aim of this present investigation was to study the relationship between the reduction in insulin sensitivity accompanying 5 days of treatment with growth hormone (GH...
Clin Sci (Lond) (2002) 102 (1): 85–90.
Published: 10 December 2001
... candidates for the use of anabolic agents, such as growth hormone, to restore lean body mass. This study included 26 HIV-infected patients and nine healthy controls, assessed previously for the effectiveness of 2 weeks of growth hormone administration in the stimulation of protein synthesis in skeletal...
Clin Sci (Lond) (2000) 99 (1): 47–56.
Published: 15 June 2000
...Sigrid JEHLE; Henry N. HULTER; Reto KRAPF Sustained administration of growth hormone (GH) to human subjects with NH 4 Cl-induced chronic metabolic acidosis (CMA) results in a large (4.5±0.5 mmol/l) increase in the plasma HCO 3 - concentration, as mediated by a large increase in renal net acid...
Clin Sci (Lond) (1995) 89 (6): 601–609.
Published: 01 December 1995
... the course of the clamp and was significantly lower than in the control subjects ( P < 0.01) 5. Growth hormone increased in response to glucose infusion in the patients but not in the control subjects. 6. Like patients suffering uncomplicated sepsis or trauma, patients with multiple organ failure are also...
Clin Sci (Lond) (1995) 88 (1): 67–71.
Published: 01 January 1995
...Olga M. Rutherford; Salem A. Beshyah; Jonathan Schott; Yvonne Watkins; Desmond G. Johnston 1. Growth hormone-deficient hypopituitary adults often complain of weakness and fatigue. The cause of the fatigue is unknown but could be an increased proportion of fast, fatiguable, type 2 fibres...
Clin Sci (Lond) (1994) 87 (5): 581–586.
Published: 01 November 1994
...) and to evaluate their clinical utility by applying them in a clinical trial involving resistance exercise and recombinant human growth hormone. 2. Sixty-four healthy older adults (39 women and 25 men), aged 65–82 years, served as subjects. The ratios of trunk fat-to-total fat, trunk fat-to-body weight, trunk fat...
Clin Sci (Lond) (1994) 87 (2): 239–243.
Published: 01 August 1994
...Stephen B. Harrap; Shari R. Datodi; Emma K. Crapper; Leon A. Bach 1. Growth hormone may influence cardiac growth during post-natal maturation or in response to hypertension, and the growth-hormone deficient dwarf rat model offers an opportunity to study this question. 2. We compared the blood...
Clin Sci (Lond) (1994) 86 (3): 233–237.
Published: 01 March 1994
...Hans Herlitz; Olof Jonsson; Bengt-Åke Bengtsson 1. The effect of treatment with recombinant human growth hormone on urinary sodium excretion, total body water, the renin-angiotensin system and erythrocyte sodium metabolism was investigated in 16 adults with growth hormone deficiency. 2. Total body...
Clin Sci (Lond) (1993) 85 (5): 607–614.
Published: 01 November 1993
... activity. The increase after γ-L-glutamyl-5-hydroxy-L-tryptophan was smaller and delayed. 5-Hydroxy-L-tryptophan, but not γ-glutamyl-5-hydroxy-L-tryptophan, increased serum growth hormone concentration. 5. There was a significant increase in diastolic blood pressure after 5-hydroxy-L-tryptophan...
Clin Sci (Lond) (1992) 83 (3): 325–330.
Published: 01 September 1992
...Franco Salomon; Ross C. Cuneo; Richard Hesp; Jenny F. Morris; Lucilla Poston; Peter H. Sönksen 1. The relationship of lean body mass, plasma insulin concentration and leucocyte active sodium transport with basal metabolic rate was investigated in 24 adults with growth hormone deficiency before...
Clin Sci (Lond) (1987) 72 (2): 181–185.
Published: 01 February 1987
...A. M. Sopwith; Elizabeth S. Penny; N. Lytras; G. M. Besser; Lesley H. Rees 1. Using a highly specific radioimmunoassay we have measured immunoreactive human growth hormone releasing factor (ir-hGRF) concentrations in the peripheral circulation of a total of 12 normal subjects. 2. Neither insulin...
Clin Sci (Lond) (1985) 68 (s10): 137s–139s.
Published: 01 January 1985
..., but there was no change on either day during guanfacine infusion. 3. Guanfacine reduced plasma noradrenaline by approximately 30%, and this was not antagonized by idazoxan. By contrast, the 30-fold increase in plasma growth hormone caused by guanfacine was almost completely blocked by idazoxan. 4. Guanfacine caused a two...
Clin Sci (Lond) (1984) 67 (2): 219–223.
Published: 01 August 1984
... group (85 ± 12 vs 180 ± 21 m-units/l). 4. No change in thyrotrophin (TSH), growth hormone (GH) or luteinizing hormone (LH) was seen during either rate of dopamine infusion compared with control. 5. While dopamine infusion at 0.1 μg min −1 kg −1 caused significant inhibition of prolactin secretion...
Clin Sci (Lond) (1982) 62 (2): 137–141.
Published: 01 February 1982
... blood pressure or heart rate during exposure to noise. 3. Adrenaline, noradrenaline, prolactin, cortisol and growth hormone concentrations in venous plasma were not affected during noise stimulation. 11 5 1981 9 9 1981 © 1982 The Biochemical Society and the Medical Research Society...
Clin Sci (Lond) (1981) 61 (5): 653–656.
Published: 01 November 1981
... with symptomatic pancreatic endocrine tumours. 2. There was a reduction by more than 50% for at least 10 h in plasma concentrations of growth hormone, glucagon, gastrin and motilin and for 4–5 h in plasma insulin, pancreatic polypeptide, gastric inhibitory polypeptide and enteroglucagon. 3. This study shows...
Clin Sci (Lond) (1980) 58 (2): 135–138.
Published: 01 February 1980
...C. Barbieri; C. Ferrari; R. Caldara; G. Curtarelli 1. In an attempt to test the hypothesis of a derangement in central catecholaminergic function in hypertensive patients, the serum growth hormone and prolactin responses to the α-adrenergic agonist clonidine (0·15 mg infused intravenously) and to l...
Clin Sci Mol Med (1977) 53 (1): 87–91.
Published: 01 July 1977
...M. H. Snow; D. A. Piercy; Valerie Robson; R. Wilkinson 1. In 29 patients with acromegaly, plasma renin activity and growth hormone were measured during fasting and recumbency on free diet. Exchangeable sodium was measured in all cases and expressed as a percentage of the expected value on the basis...
Clin Sci Mol Med (1976) 50 (6): 551–554.
Published: 01 June 1976
...O. T. Phillipson; E. D. Bird 1. Growth hormone secretion was assessed in nine control subjects and nine patients with Huntington's chorea. 2. Early-morning fasting plasma samples from patients with Huntington's chorea contained abnormally high concentrations of growth hormone. 3. The suppression...
Clin Sci Mol Med (1976) 50 (4): 241–247.
Published: 01 April 1976
... growth hormone (HGH), lactic acid and hydrogen ion concentration ([H + ])weremeasured at frequent intervals. 2. Ammonium chloride produced highest blood [H + ] and NaHCO 3 the lowest. These differences were maintained during exercise and in recovery. Plasma lactic acid concentrations were similar at rest...
Clin Sci Mol Med (1975) 49 (5): 473–479.
Published: 01 November 1975
.... Serum growth hormone concentrations showed a paradoxical increase after glucose. 5. All these variables had returned to normal in four patients re-tested after recovery. 3 6 1975 © 1975 The Biochemical Society and the Medical Research Society 1975 glucose tolerance growth hormone...
Clin Sci Mol Med (1975) 49 (3): 201–206.
Published: 01 September 1975
... Cortisol increased after the subject pushed for 3 min at 50% of maximum force. 2. Holding a 20 kg weight for 5 min in one hand caused a rise in plasma Cortisol and in plasma ACTH but no changes in growth hormone were observed. 26 2 1975 © 1975 The Biochemical Society and the Medical Research...
Clin Sci Mol Med (1973) 45 (5): 633–654.
Published: 01 November 1973
... hormone and Cortisol were shown to be directly related to the degree of hypoglycaemia induced. 14 3 1973 © 1973 The Biochemical Society and the Medical Research Society 1973 human insulin porcine proinsulin metabolism growth hormone Cortisol plasma glucose Clinical Science...
Clin Sci Mol Med (1973) 45 (3): 387–396.
Published: 01 September 1973
... and hypoglycaemic unresponsiveness as shown by a greater and more sustained fall in glucose concentration following intravenous administration of tolbutamide. 4. Basal growth hormone concentrations are within the normal range and do not rise paradoxically after glucose administration. 5. These findings in hepatoma...
Clin Sci (1972) 43 (1): 71–77.
Published: 01 July 1972
...Y. C. Patel; F. P. Alford; H. G. Burger 1. Daily fluctuations in the plasma concentrations of thyroid stimulating hormone (TSH) and growth hormone (GH) have been studied in six normal males by using a 24 h continuous blood-sampling technique and a highly sensitive and specific radioimmunoassay...