... enhances the incidence or severity of acute kidney injury (AKI). diabetic nephropathy glucose transport renal physiology Type 2 diabetes mellitus (T2DM) is a major public health concern [ 1 ]. The main feature of T2DM is chronic or periodic hyperglycemia which in turn can lead to progression...

... glucose transport or suppression of lipolysis was observed. In conclusion, despite the observation that dietary sodium restriction was associated with a median 15% reduction in insulin sensitivity, we found no evidence of a direct effect of AII on insulin action in human adipocytes. dietary sodium...

.... By autoradiography, we have also shown that specific binding of glucagon occurs in both the renal cortex and medulla. In addition, using proximal tubule brush-border membrane (BBM) vesicles for studies of glucose transport, we have established that glucagon stimulates glucose uptake via a facilitative GLUT-mediated...

... activity on non-myofibrillar proteins, and what information is available indicates that changes in the expression of specific proteins can be influ- enced by the type of experimental model of disuse being used. For example, the expression of the GLUT4 glucose transporter is significantly reduced...

...Jonathan B. Meddings; Henrik Westergaard 1. The transport model that best describes intestinal glucose transport in vivo remains unsettled. Three models have been proposed: (1) a single carrier, (2) a single carrier plus passive diffusion, and (3) a two-carrier system. The objectives of the current...

...J. Telch; R. W. Shepherd; D. G. Butler; M. Perdue; J. R. Hamilton; D. G. Gall 1. We studied intestinal glucose transport in pigs during the acute and convalescent phases of an invasive viral enteritis, transmissible gastroenteritis. 2. When diarrhoea was severe 40 h after experimental infection...

... the existence of a co-transport mechanism, whereas the absence of an effect on sodium transport in volume-expanded dogs despite complete inhibition of glucose reabsorption indicates the existence of a sodium-independent component of net proximal tubular glucose transport. 6. Absence of the effect of phlorhizin...

...S.-F. Wen; J. W. Boynar, Jr; R. W. Stoll 1. In order to study the relationship between sodium and glucose transport along the nephron, clearance and micropuncture experiments were performed in 16 dogs before and after administration of diuretics with different sites of action. 2. Administration...