... to insulin stimulation compared with WT mice. Our study establishes a new and important function of AKT2 in regulating skeletal muscle development and glucose metabolism via AMPK-dependent signaling. After extensive proliferation, myoblasts undergo differentiation and fusion with each other or existing...

... ex vivo respiration in, human skeletal muscle. adrenaline glucose metabolism lactate mitochondrial respiration stable isotope three-compartment model • Although plasma lactate is an important and frequently used laboratory test, the metabolism of lactate is still not fully...

... mortality in these patients. Correspondence: Dr Nick Wlazlo (email nickwlazlo@gmail.com ). 5 11 2012 18 3 2013 8 4 2013 8 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 chronic liver disease diabetes glucose metabolism infections...

... born with low birthweight, but afterwards they had catch-up growth, reaching the weight of the CC1 offspring. The increased glycaemia in RC1 offspring was associated with insulin resistance. CR1 and RR1 offspring had impaired growth with no changes in glucose metabolism. RC2 offspring had high BM (body...

... secretion and β-cell integrity. Pancreatic β-cell and islet glucose metabolism results in increased levels of cytosolic long-chain acyl-CoA compounds, TAG (triacylglycerol) and phospholipid turnover as a consequence of increased citrate and malonyl-CoA production and subsequent inhibition of β-oxidation...

...) was calculated from the GIR (glucose infusion rate), corrected for body weight, during the final 30 min as follows: glucose metabolism haemodilution hydration pharmacokinetics Type II diabetes volume kinetics As many as 30–40% of geriatric patients are undernourished and probably also...

...Luc J. C. VAN LOON; Robyn MURPHY; Audrey M. OOSTERLAAR; David CAMERON-SMITH; Mark HARGREAVES; Anton J. M. WAGENMAKERS; Rodney SNOW It has been speculated that creatine supplementation affects muscle glucose metabolism in humans by increasing muscle glycogen storage and up-regulating GLUT-4 protein...

... acid and glucose metabolism in a porcine model of compensated hyperdynamic sepsis. Fasting catheterized pigs received endotoxin ( Escherichia coli lipopolysaccharide; 3 µ g·h -1 ·kg -1 ; intravenous) or saline (controls) and volume resuscitation over 24h to reproduce hyperdynamic sepsis. Primed...

... ). © 2002 The Biochemical Society and the Medical Research Society 2002 endothelin insulin glucose metabolism hexosamine 418S Clinical Science (2002) 103 (Suppl. 48), 418S 423S (Printed in Great Britain) Endothelin-stimulated glucose uptake: effects of intracellular Ca2+, cAMP...

... Hospital, Box 4622, 116 91 Stockholm, Sweden (e-mail jonas.nygren@ersta.se ). 8 10 2001 4 12 2001 The Biochemical Society and the Medical Research Society © 2002 2002 glucose clamp technique glucose metabolism growth hormone insulin resistance protein metabolism. 457Clinical...

... Society © 2000 2000 glucose clamp technique glucose metabolism glucose tracers reproducibility 367Clinical Science (2000) 98, 367 374 (Printed in Great Britain) The hyperinsulinaemic euglycaemic glucose clamp: reproducibility and metabolic effects of prolonged insulin infusion in healthy...

...Olga LABUDOVA; Erwin KITZMUELLER; Hermann RINK; Nigel CAIRNS; Gert LUBEC Impaired glucose metabolism in Down's syndrome (DS) has been well-documented in vivo , although information on the underlying biochemical defect is limited and no biochemical studies on glucose handling enzymes have been...

... ingestion is similar in the two tissues. blood flow glucose metabolism insulin lipid mobilization microdialysis Clinical Science (1998) 94,7 1-77 (Printed in Great Britain) 71 lipolysis and lactate production in human skeletal muscle and adipose tissue following glucose ingestion Danielle A. 1. M...

... on endogenous glucose production. 7 3 1997 27 3 1997 © 1997 The Biochemical Society and the Medical Research Society 1997 fasting glucose clamp technique glucose metabolism insulin resistance stable isotopes Clinical Science (1997) 93, 137-146 (Printed in Great Britain) Site...

...J. P. H. Wilding; Y. T. Kruszynska; P. D. Lambert; S. R. Bloom 1. Neuropeptide Y is a potent appetite stimulant and has been found to modulate glucose metabolism when given chronically. The acute effects of neuropeptide on peripheral glucose handling have not been studied in detail. We have studied...

... 11 1994 5 1 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 continuous ambulatory peritoneal dialysis diabetes mellitus glucose metabolism intraperitoneal insulin insulin action insulin sensitivity serum lipids subcutaneous insulin Clinical...

... and the Medical Research Society 1993 cytokines glucose metabolism prostaglandins Clinical Science (1993) 85, 679-685 (Printed in Great Britain) lndomethacin stimulates basal glucose production in humans without changes in concentrations of glucoregulatory hormones E. P. M. CORSSMIT', J. A. ROMIJN's* E...

... in the presence of lower insulin concentrations. If NIMGU is considerably increased in HIV infection, the contribution of IMGU will be overestimated. Consequently, an increment in insu- Key words: acquired immunodeficiency syndrome, glucose metabolism, insulin sensitivity, isotope dilution, non-insulin-mediated...

... and diminished sensitivity, affects both fat and carbohydrate metabolism, and must be explained by factors other than the usually considered 'counter-regulatory ' hormones. Key words: carbohydrate oxidation, energy production, fat oxidation, forearm glucose uptake, glucose metabol- ism, injury, insulin...

... during continuous ambulatory peritoneal dialysis, but hepatic insulin action was unchanged. 6 3 1989 20 3 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 chronic renal failure continuous ambulatory peritoneal dialysis glucose metabolism insulin action...

...Brendan Leighton; George D. Dimitriadis; Mark Parry-Billings; Jane Bond; Paulo R. L. de Vasconcelos; Eric A. Newsholme 1. The effects of non-lethal bacteraemia or endotoxaemia on insulin-stimulated glucose metabolism were studied in isolated, incubated soleus muscle of rats after 24 and 48 h. 2...

... Research Society 1982 glucose kinetics glucose metabolism glucose turnover mass spectrometry stable isotopes tracer methodology Clinical Science (1982) 63,431440 437 Assessment of glucose turnover in normal man with the use of a non-radioactive isotopically labelled preparation, [6,6-2H...

...+ by forearm tissues. 4. This is the first demonstration of the stimulatory effects of digoxin on glucose metabolism, the antilipolytic effects of this drug and its effect on Ca 2+ fluxes in vivo in man. 27 9 1971 © 1972 The Biochemical Society and the Medical Research Society 1972 forearm...

... creatinine methylguanidine glucose metabolism Clinical Science (1972) 42, 395401. EFFECTS O F URAEMIC S E R U M , U R E A , CREATININE A N D M E T H Y L G U A N I D I N E O N GLUCOSE METABOLISM P. L. BALESTRI, P. RINDI , M. BIAGINI AND S. GIOVANNETTI Divisione Nefrologica, Ospedali S. Chiara, Pisa...