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Keywords: fatty acids
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Articles
Clin Sci (Lond) (2022) 136 (24): 1773–1791.
Published: 13 December 2022
...Aliye Uc; Birgitta Strandvik; Jianrong Yao; Xiaoming Liu; Yaling Yi; Xingshen Sun; Ruth Welti; John F. Engelhardt; Andrew W. Norris Persons with cystic fibrosis (CF) exhibit a unique alteration of fatty acid composition, marked especially among polyunsaturates by relative deficiency of linoleic...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (12): 1329–1342.
Published: 07 June 2017
...). Glutamine plays an essential role in macrophage metabolism and function, as it is required for energy production but also provides nitrogen for synthesis of purines, pyrimidines and thus RNA. Macrophages also utilize fatty acids for both energy production in the mitochondria and lipid synthesis essential...
Articles
Clin Sci (Lond) (2002) 102 (4): 403–409.
Published: 05 March 2002
...G. PRIANTE; L. BORDIN; E. MUSACCHIO; G. CLARI; B. BAGGIO Epidemiological, clinical and experimental evidence suggests that fatty acids have a modulatory effect on bone metabolism in animals and humans. To investigate this hypothesis, we evaluated the effects of three different fatty acids...
Articles
Clin Sci (Lond) (2001) 100 (5): 517–527.
Published: 03 April 2001
... exercise increased postprandial serum 3-hydroxybutyrate and plasma fatty acid concentrations, decreased serum postprandial insulin concentrations and increased exogenous (8 h 13 C breath excretion of 15.1±0.9% of ingested dose compared with 11.9±0.8%; P = 0.00001) and endogenous postprandial fat oxidation...
Articles
Clin Sci (Lond) (2000) 99 (4): 321–328.
Published: 05 September 2000
... in five normal subjects and in five patients with severe sepsis hospitalized in an intensive care unit. The responses of endogenous glucose production, glucose utilization, plasma fatty acids and ketone body concentrations to progressive increase in plasma insulin levels (exogenous insulin infusion rates...
Articles
Clin Sci (Lond) (2000) 99 (3): 169–174.
Published: 01 August 2000
...Lars LIND; Andreas FUGMANN; Stefan BRANTH; Bengt VESSBY; Jonas MILLGÅRD; Christian BERNE; Hans LITHELL Dyslipidaemia, with elevations of circulating triacylglycerols (triglycerides) and non-esterified (free) fatty acids, and hyperinsulinaemia are often found in the same subjects, the so-called...
Articles
Clin Sci (Lond) (1996) 91 (4): 509–512.
Published: 01 October 1996
...Stephen P. Pereira; Theresa B. Cassell; Jeffrey L Engelman; Gordon E. Sladen; Gerard M. Murphy; R. Hermon Dowling 1. Increased concentrations of plasma polyunsaturated fatty acids have been implicated in the pathogenesis of Crohn's disease. However, it is not known whether there are corresponding...
Articles
Clin Sci (Lond) (1992) 82 (6): 695–700.
Published: 01 June 1992
...Philip C. Calder; Eric A. Newsholme 1. The effects of a variety of fatty acids on human peripheral blood lymphocyte proliferation stimulated by concanavalin A or purified protein derivative of Mycobacterium tuberculosis were studied. 2. The proliferative response to concanavalin A was inhibited...
Articles
Clin Sci (Lond) (1992) 82 (1): 99–104.
Published: 01 January 1992
...J. F. St. J. Dwight; A. C. Mendes Ribeiro; B. M. Hendry 1. Sodium pump function has been assessed by measurement of ouabain-sensitive 86 Rb uptake in human erythrocytes after incorporation of palmitic, stearic, oleic and linoleic acids into the erythrocyte membrane. 14 C-labelled fatty acids were...
Articles
Clin Sci (Lond) (1990) 79 (4): 349–355.
Published: 01 October 1990
...D. R. Fine; P. L. Zentler-Munro; T. C. Northfield 1. The efficiencies of three different methods of inhibiting fatty acid production in chyme have been evaluated. The effects of each method on the phase distribution of fatty acids after ultracentrifugation have been studied. 2. Chyme fatty acid...
Articles
Clin Sci (Lond) (1987) 73 (4): 361–364.
Published: 01 October 1987
... the fatty acid concentrations. 3. Seventy-five to ninety-five per cent of the arachidonic acid was found in the phospholipid fraction after separation by thin-layer chromatography. There were no significant changes in the concentrations of the other fatty acids measured, although oleic acid was lower...
Articles
Clin Sci (Lond) (1986) 71 (6): 737–742.
Published: 01 December 1986
...L. L. Ng; T. D. R. Hockaday 1. Human leucocyte sodium pump activity was studied in normal fasting subjects by measuring the ouabain-sensitive 22 Na + efflux rate constants. 2. This 22 Na + efflux rate constant was inversely related to the fasting plasma non-esterified fatty acid level ( r s = −0.73...
Articles
Clin Sci (Lond) (1985) 68 (5): 581–587.
Published: 01 May 1985
...M. Boberg; L. B. Croon; I.-B. Gustafsson; B. Vessby 1. The fatty acid composition in platelet phospholipids and in the plasma lipid esters as well as the serum lipoprotein lipid concentrations were determined in 67 healthy male subjects in order to establish the relationships between blood lipids...
Articles
Clin Sci (Lond) (1983) 65 (6): 645–652.
Published: 01 December 1983
... decrease in alcoholic cirrhosis compared with controls. 3. Fatty acid ester analysis of hepatic phospholipid and triglyceride revealed significant differences between alcoholic patients and controls but not between diabetic patients and controls. An increased ratio of non-essential/essential fatty acids...
Articles
Clin Sci (Lond) (1983) 65 (3): 247–253.
Published: 01 September 1983
.... There was a small increase in arterial blood glucose concentration, and a decrease in blood alanine concentration during drug infusion. Blood lactate was not affected by phentolamine. The arterial concentrations of free fatty acids and glycerol increased, and the concentration of triglycerides decreased during...
Articles
Clin Sci (Lond) (1979) 56 (5): 493–499.
Published: 01 May 1979
...G. Y. Ma; C. D. Gove; M. A. Cawthorne; D. A. Hems 1. Rapid effects of hormones on the metabolism of glycogen and fatty acids were studied in the perfused liver of normal and genetically obese ( ob / ob ) mice. 2. In livers from normal and obese mice adrenaline and angiotensin II stimulated...
Articles
Clin Sci Mol Med (1978) 54 (3): 241–249.
Published: 01 March 1978
... this represents a form of functional adaptation by the colon to ileal resection. 23 3 1977 2 9 1977 © 1978 The Biochemical Society and the Medical Research Society 1978 adenosine 3′:5′-phosphate bile acids colonic adaptation fatty acids intestinal resection ...
Articles
Clin Sci Mol Med (1976) 51 (3): 257–265.
Published: 01 September 1976
... insulin levels were greater in the hypertriglyceridaemic group than in the normotriglyceridaemic group. The difference in esterification rates could have been due to differences in adipocyte size. 4. The esterification of fatty acid in adipose tissue of diabetic patients was lower than in non-diabetic...
Articles
Clin Sci Mol Med (1973) 44 (1): 55–62.
Published: 01 January 1973
... Society 1973 biguanide fatty acids glucose uptake insulin skeletal muscle Clinical Science (1973) 44,55-62. THE USE O F H U M A N SKELETAL MUSCLE I N YITRO FOR BIOCHEMICAL A N D PHARMACOLOGICAL STUDIES O F GLUCOSE UPTAKE K. N. FRAYN,* P. I . ADNITTT AND P. T U R N E R Department of Clinical...