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Keywords: endotoxin
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Clin Sci (Lond) (2016) 130 (6): 451–461.
Published: 04 February 2016
... endotoxin tolerance in endothelial cells. Most importantly, MPLA, a vaccine adjuvant with a wide therapeutic window, induced tolerance to LPS in endothelial cells. RNA was isolated from cultured cells via GenElute Mammalian Total RNA Miniprep Kit (Sigma) following the manufacturer's instructions at 6 h...
Includes: Supplementary data
Clin Sci (Lond) (2012) 123 (11): 627–634.
Published: 01 August 2012
... at non-weight-bearing joints which cannot be explained by biomechanical factors. endotoxaemia endotoxin lipopolysaccharide obesity osteoarthritis CRP is another pro-inflammatory factor positively correlated with BMI in otherwise healthy individuals, and its elevation in obesity may...
Clin Sci (Lond) (2010) 118 (6): 421–427.
Published: 14 December 2009
...Rokhsareh F. Vesali; Norbert Cibicek; Towe Jakobsson; Maria Klaude; Jan Wernerman; Olav Rooyackers The human endotoxin model has been used to study the early phase of sepsis. The aim of the present study was to assess leg muscle protein kinetics after an endotoxin challenge given to healthy human...
Clin Sci (Lond) (2004) 106 (6): 577–581.
Published: 01 June 2004
... endotoxin [LPS (lipopolysaccharide), 20 units/kg of body mass; n =8] or placebo ( n =9) in healthy males. L -Arginine and dimethylarginines were quantified after solid-phase extraction by reversed-phase HPLC. Body temperature, heart rate and leucocyte count increased after LPS administration ( P <0.01...
Clin Sci (Lond) (2001) 101 (3): 267–274.
Published: 03 August 2001
..., TX 77555–0876, U.S.A. (e-mail theming@utmb.edu ). 20 4 2001 18 5 2001 The Biochemical Society and the Medical Research Society © 2001 2001 acidbase cytokine endotoxin leucocyte tumour necrosis factor- 267Clinical Science (2001) 101, 267 274 (Printed in Great Britain...
Clin Sci (Lond) (1997) 92 (4): 415–422.
Published: 01 April 1997
... of the inflammatory response to exercise were measured: polymorphonuclear myeloperoxidase (MPO), anaphylatoxin C5a (C5a), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6). Plasma endotoxin was measured by a sensitive and rapid chromogenic Limulus assay. All inflammatory markers were significantly increased...
Clin Sci (Lond) (1995) 88 (1): 59–66.
Published: 01 January 1995
...H. T. Besler; R. F. Grimble 1. n -3 polyunsaturated fatty acids decrease responses to cytokines and inflammatory agents. The present study examines how different intakes of n -6 and n -9 fatty acids influence the metabolic response to endotoxin in Wistar rats. 2. Weanling male rats were, for 4...
Clin Sci (Lond) (1994) 87 (4): 459–465.
Published: 01 October 1994
... behaviour of an intravenously injected bolus of recombinant human tumour necrosis factor-α (50 μg/m 2 ) in another group of six normal subjects. We then calculated the total amount of tumour necrosis factor-α produced after intravenous injection of endotoxin (2 ng/kg) as the product of the systemic...
Clin Sci (Lond) (1994) 87 (2): 179–186.
Published: 01 August 1994
...H. Terence Cook; Alison J. Bune; Albertine S. Jansen; G. Michael Taylor; Rashpal K. Loi; Victoria Cattell 1. Endotoxin induces a shock-like syndrome with increased nitric oxide synthesis. To clarify the cellular source of NO in endotoxic shock we used immunohistochemistry and in situ hybridization...
Clin Sci (Lond) (1993) 84 (3): 247–256.
Published: 01 March 1993
...Tom van der Poll; Hans P. Sauerwein © 1993 The Biochemical Society and the Medical Research Society 1993 cytokines endotoxin fat glucose metabolism sepsis stress hormones tumor necrosis factor-α Clinical Science (1993) 84, 247-256 (Printed in Great Britain) Editorial Review...
Clin Sci (Lond) (1991) 81 (3): 357–365.
Published: 01 September 1991
... failure syndrome and death within 42 h of a continuous intravenous infusion of Escherichia coli endotoxin (40 ng min −1 kg −1 ). 2. Plasma and pulmonary lymph endothelin-like immunoreactivity were measured by r.i.a. using a specific antiserum raised in rabbits against porcine endothelin-1. Endothelin-like...
Clin Sci (Lond) (1990) 79 (6): 619–623.
Published: 01 December 1990
... endotoxin Escherichia coli Gram-negative bacteraemia lipopolysaccharide tumour necrosis factor-α Clinical Science (1 990) 79, 6 19-623 619 Endothelin immunoreactivity in mice with Gram-negative bacteraemia: relationship to tumour necrosis factor- a KAZUHIRO TAKAHASHI, AYONA SILVA*, JONATHAN COHEN...
Clin Sci (Lond) (1989) 77 (1): 61–67.
Published: 01 July 1989
... of glycolysis to insulin. 4. Endotoxaemia decreased the rates of glycogen synthesis at all concentrations of insulin both at 24 h (∼ 39%) and 48 h (∼ 23%). 5. The increase in the rate of glycolysis was related in a dose-dependent manner to the amount of endotoxin given to the animals. 6. Endotoxaemia decreased...
Clin Sci (Lond) (1989) 76 (6): 659–666.
Published: 01 June 1989
...S. A. Ash; G. E. Griffin 1. Intravenous infusion of endotoxin into rats over 18 h caused a reduction in food intake to 20% of normal levels, weight loss, hypoalbuminaemia and a fall in rates of protein synthesis in vivo in heart and skeletal muscle. 2. Measurements of protein turnover in vitro...
Clin Sci Mol Med (1978) 54 (6): 615–620.
Published: 01 June 1978
...J. P. Nolan; R. C. Venuto; Gwendolyn S. Goldmann 1. A relationship between bacterial endotoxin absorbed from the gut and acute renal failure has been postulated. Experiments employing either the endotoxin-tolerant state or the enhancement of endotoxin injury were undertaken to test...