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Keywords: diuretic
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Clin Sci (Lond) (2014) 126 (10): 721–726.
Published: 03 February 2014
...-dependent form of hypertension caused by mutations in the regulators of the thiazide-sensitive Na + –Cl − co-transporter NCC [also known as SLC12A3 (solute carrier family 12 member 3)] and is effectively treated by thiazide diuretics and/or dietary salt restriction. Variation in at least four genes can...
Clin Sci (Lond) (2011) 121 (11): 509–521.
Published: 09 August 2011
...Ying-Ying Yang; Han-Chieh Lin; Ming-Wei Lin; Chi-Jen Chu; Fa-Yauh Lee; Ming-Chih Hou; Shou-Dong Lee; Wei-Ping Lee; Tze-Tze Liu; Tjin-Shing Jap In cirrhosis, the development of ascites and the response to diuretics are determined by the RAAS (renin–angiotensin–aldosterone system) and renal sodium...
Includes: Supplementary data
Clin Sci (Lond) (2007) 112 (4): 203–216.
Published: 17 January 2007
... provide the basis for developing new therapeutic approaches to essential hypertension. Correspondence: Dr Peter W. Flatman (email peter.flatman@ed.ac.uk ). 18 8 2006 8 9 2006 14 9 2006 The Biochemical Society 2007 diuretic hypertension serine/threonine protein kinase...
Clin Sci (Lond) (1983) 64 (6): 565–572.
Published: 01 June 1983
...Thomas Kahn; Allen M. Kaufman; Fernand L. Mac-Moune 1. in animals on a normal NaCl intake despite the repeated administration of a diuretic Cl and Na excretion return to baseline values after initial Cl and Na loss. in order to delineate whether this apparent resistance is consequent primarily...
Clin Sci (Lond) (1982) 63 (s8): 403s–405s.
Published: 01 October 1982
... be important in the genesis of mild hypertension. © 1982 The Biochemical Society and the Medical Research Society 1982 β-adrenoceptor antagonist coffee diuretic hypertension smoking Clinical Science (1982) 63,4039-403s 403 s Pressor effect of coffee and cigarette smoking in hypertensive patients...
Clin Sci (Lond) (1980) 59 (6): 443–449.
Published: 01 December 1980
... of observation. 3. These haemodynamic changes occurred in the absence of major hormonal fluctuations and related presumably to direct vascular and diuretic actions of frusemide. 4. With more chronic (8–10 days) oral frusemide therapy, reciprocal changes between haemodynamic and hormone indices were observed...
Clin Sci Mol Med (1978) 55 (s4): 151s–153s.
Published: 01 December 1978
... (544 μmol)/day; and hydrochlorothiazide, 50 mmol of sodium and indomethacin 100 mg (287 μmol)/day. 2. Although blood pressure remained unchanged and serum potassium fell on diuretic with or without low salt, there was a marked increase of active renin and a lesser increase of inactive renin, resulting...
Clin Sci Mol Med (1977) 53 (4): 379–386.
Published: 01 October 1977
...K. Lau; R. M. Stote; M. Goldberg; Z. S. Agus 1. We have studied the effects of the diuretic tienilic acid (Ticrynafen) upon renal tubular transport of urate, in 11 healthy volunteers on a constant dietary intake. 2. Daily administration of tienilic acid for 10 days to six subjects reduced the mean...
Clin Sci Mol Med (1976) 51 (s3): 517s–519s.
Published: 01 December 1976
... mmHg during the combined timolol plus hydrochlorothiazide phase. 3. Factorial analysis revealed that the hypotensive actions of the β-receptor-blocking drug and the diuretic were additive, without any synergism or antagonism. 4. Plasma renin activity measured in ng 3 h —1 ml —1 rose from 502...