... and proapoptotic genes after IS [ 13 ]. A systemic inflammatory response is triggered in response to IS [ 14 ]. Previous studies have reported PBMCs as appropriate sources of potential biomarkers for the diagnosis and prediction of stroke [ 15 , 16 ]. Furthermore, Bam and colleagues [ 17 ] reported dysregulation...

... circulating lncRNA coronary artery disease diagnosis long non-coding RNA • CAD is the major cause of death worldwide; a lot of patients with acute coronary syndrome or severe coronary stenosis have benefited from the improved therapeutic methods in clinics, including medications, percutaneous...

...@163.com ) 29 8 2014 24 11 2014 9 12 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 diagnosis individualized treatment miRNA non-small-cell lung cancer (NSCLC) post-transcriptional regulation prognosis Lung cancer remains the leading...

... factor)-binding protein 2] levels. Final diagnosis and death during follow-up were adjudicated blinded to LTBP2 levels. AHF (acute heart failure) was the final diagnosis in 54% of patients. In both AHF ( P <0.001) and non-AHF ( P =0.015) patients, LTBP2 levels at presentation were significantly higher...

... diagnosis hypertension kidney microRNA (miRNA) therapy translational research miRNAs (microRNAs) are endogenously produced non-coding RNA molecules approximately 22 nucleotides long that play a ubiquitous and important role in regulating protein expression ( Figure 1 A). miRNAs, and non-coding...

... Biochemical Society 2011 diagnosis oesophageal squamous cell carcinoma (ESCC) microRNA miR-31 prognosis Three ESCC cell lines, EC9706 (established in our laboratory) [ 25 ], KYSE150 and KYSE510 (gifts from Dr Y. Shimada, First Department of Surgery, Kyoto University, Kyoto, Japan) [ 26...

...Iain B. Squire; Christopher P. Nelson; Leong L. Ng; David R. Jones; Kent L. Woods; Paul C. Lambert The diagnosis of diabetes and admission blood glucose concentration are associated with adverse outcome after acute coronary syndromes. We compared the relative association with survival after ST...

... marked benefits in treating asymptomatic patients [ 9 ], it is clear that early detection of LV (left ventricular) dysfunction and intervention to prevent, or at least delay, the clinical manifestations of HF is essential to contain this pandemic. Unfortunately, the accurate diagnosis of HF can...

.... Correspondence: Dr Rayaz A. Malik (email Rayaz.A.Malik@man.ac.uk ). 23 2 2004 20 8 2004 2 9 2004 2 9 2004 The Biochemical Society 2004 diabetic cardiomyopathy diagnosis echocardiography molecular mechanism treatment The epidemic of obesity and sedentary lifestyle...

... in this issue of Clinical Science that urinary levels of N-BNP may be as useful as plasma levels for the discrimination of patients with and without heart failure. This raises the potential for a relatively simple urine test that could be used for the diagnosis of heart failure. Roles in prognostication...

...L. L. NG; S. GEERANAVAR; S. C. JENNINGS; I. LOKE; R. J. O'BRIEN In the present study, we assessed the use of urinary natriuretic peptides [N-terminal proatrial natriuretic peptide (N-ANP) and N-terminal pro-brain natriuretic peptide (N-BNP) and C-type natriuretic peptide (CNP)] in the diagnosis...

...Arzu ENSARI; Michael N. MARSH; Shethah MORGAN; Robert LOBLEY; D. J. UNSWORTH; Daphne KOUNALI; Peter T. CROWE; Jane PAISLEY; Kieran J. MORIARTY; John LOWRY The purpose of this study was to evaluate the use of rectal gluten challenge in the diagnosis of coeliac disease. A total of 103 patients...

... of infection. 5. Measurement of intercellular adhesion molecule-1 level may have a clinical role in rapidly confirming, or predicting, the likely diagnosis in cases of suspected neonatal infection. 18 10 1993 21 1 1994 14 2 1994 © 1994 The Biochemical Society and the Medical Research...

... The Biochemical Society and the Medical Research Society 1970 adenine phosphoribosyltransferase deficiency diagnosis Clinical Science (1988) 75,217-220 217 Adenine phosphoribosyltransferase deficiency: a simple diagnostic test J. L. MADDOCKS AND S. A. AL-SAFI University Department of Therapeutics...

... concentration when present, coupled with adrenal venous sampling, provided the best indicators of the presence of an aldosterone-producing adenoma. adenoma aldosterone diagnosis potassium primary aldosteronism sodium © 1982 The Biochemical Society and the Medical Research Society 1982 Clinfcal...