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Angiotensin-(1–7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice

Yixuan Shi, Chao-Sheng Lo, Ranjit Padda, Shaaban Abdo, Isabelle Chenier, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S.D. Chan
Journal: Clinical Science
Clin Sci (Lond) (2015) 128 (10): 649–663.
DOI: https://doi.org/10.1042/CS20140329
Published: 20 February 2015
... under sodium pentobarbital anaesthesia. Mice were killed by sodium pentobarbital overdose [75 mg/kg of BW (body weight)], and efforts were made to minimize suffering. angiotensin-(1–7) diabetic mouse kidney injury oxidative stress Male heterozygous Akita mice (C57BL/6-Ins2 Akita /J...
View article titled, Angiotensin-(1–7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice
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Includes: Supplementary data