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Keywords: cyp2c70
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Clin Sci (Lond) (2024) 138 (1): 61–64.
Published: 10 January 2024
... in the Cyp2c70 knock-out mice, which are considered as a promising ‘humanized’ experimental resource for studying bile acids and their role in pathological conditions. We also discuss how Cyp2c70 -deficient mice contribute to enhancing the translatability of preclinical studies in murine models to humans...
Clin Sci (Lond) (2023) 137 (21): 1637–1650.
Published: 10 November 2023
...Esther Verkade; Wenqiang Shen; Milaine V. Hovingh; Niels L. Mulder; Krisztina de Bruyn; Martijn Koehorst; Hilde D. de Vries; Vincent W. Bloks; Folkert Kuipers; Jan Freark de Boer Cyp2c70 -deficient mice have a human-like bile acid (BA) composition due to their inability to convert chenodeoxycholic...
Includes: Supplementary data