...@cruzeirodosul.edu.br ) * These authors contributed equally to this work. 07 08 2020 08 12 2020 04 01 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Coronavirus glutamate Glutamine Inhibitors Glutaminolysis Metabolic...

...Carlos M. Ferrario; Sarfaraz Ahmad; Leanne Groban The virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the aggressive nature of the disease has transformed the universal pace of research in the desperate attempt to seek effective therapies to halt...

... and serendipitously as a viral receptor, mediating the cellular entry of the coronaviruses causing severe acute respiratory syndrome (SARS) and, very recently, COVID-19. Catalytically, ACE2 functions as a monocarboxypeptidase principally converting the vasoconstrictor angiotensin II to the vasodilatory peptide Ang-(1...

... for any inconvenience caused to the reader. © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . Coronavirus COVID-19 signaling...

...Daniella S. Battagello; Guilherme Dragunas; Marianne O. Klein; Ana L.P. Ayub; Fernando J. Velloso; Ricardo G. Correa The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of coronaviruses – the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – discovered...

...Rhian M. Touyz; Hongliang Li; Christian Delles Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Co rona vi rus D isease (COVID...

...Daniel Batlle; Jan Wysocki; Karla Satchell A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of January...

... (transmissible gastroenteritis virus) and PDEV, (porcine diarrhoea epidemic virus)], feline [FIPV (feline infectious peritonitis virus)] and canine coronaviruses; Group 2 contains HuCoV-OC43 along with MHV (mouse hepatitis virus), bovine coronavirus and haemagglutinating encephalomyelitis virus; and Group 3...