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Sandro Massao Hirabara, Renata Gorjao, Adriana Cristina Levada-Pires, Laureane Nunes Masi, Elaine Hatanaka, Maria Fernanda Cury-Boaventura, Eliane Borges da Silva, Laiane Cristina dos Santos-Oliveira, Vinicius Leonardo Sousa Diniz, Tamires Afonso Duarte Serdan, Vivian Araujo Barbosa de Oliveira, Diego Ribeiro de Souza, Raquel Bragante Gritte, Talita Souza-Siqueira, Raquel Freitas Zambonatto, Tania Cristina Pithon-Curi, Roberto Barbosa Bazotte, Philip Newsholme, Rui Curi
Clin Sci (Lond) (2021) 135 (2): 305–325.
Published: 22 January 2021
...@cruzeirodosul.edu.br ) * These authors contributed equally to this work. 07 08 2020 08 12 2020 04 01 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 Coronavirus glutamate Glutamine Inhibitors Glutaminolysis Metabolic...
Clin Sci (Lond) (2020) 134 (19): 2645–2664.
Published: 16 October 2020
...Carlos M. Ferrario; Sarfaraz Ahmad; Leanne Groban The virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the aggressive nature of the disease has transformed the universal pace of research in the desperate attempt to seek effective therapies to halt...
Clin Sci (Lond) (2020) 134 (18): 2489–2501.
Published: 29 September 2020
... and serendipitously as a viral receptor, mediating the cellular entry of the coronaviruses causing severe acute respiratory syndrome (SARS) and, very recently, COVID-19. Catalytically, ACE2 functions as a monocarboxypeptidase principally converting the vasoconstrictor angiotensin II to the vasodilatory peptide Ang-(1...
Clin Sci (Lond) (2020) 134 (17): 2315–2317.
Published: 09 September 2020
... for any inconvenience caused to the reader. © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . Coronavirus COVID-19 signaling...
Daniella S. Battagello, Guilherme Dragunas, Marianne O. Klein, Ana L.P. Ayub, Fernando J. Velloso, Ricardo G. Correa
Clin Sci (Lond) (2020) 134 (16): 2137–2160.
Published: 21 August 2020
...Daniella S. Battagello; Guilherme Dragunas; Marianne O. Klein; Ana L.P. Ayub; Fernando J. Velloso; Ricardo G. Correa The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of coronaviruses – the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – discovered...
Clin Sci (Lond) (2020) 134 (7): 747–750.
Published: 07 April 2020
...Rhian M. Touyz; Hongliang Li; Christian Delles Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Co rona vi rus D isease (COVID...
Clin Sci (Lond) (2020) 134 (5): 543–545.
Published: 13 March 2020
...Daniel Batlle; Jan Wysocki; Karla Satchell A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of January...
Clin Sci (Lond) (2006) 110 (2): 193–204.
Published: 17 January 2006
... (transmissible gastroenteritis virus) and PDEV, (porcine diarrhoea epidemic virus)], feline [FIPV (feline infectious peritonitis virus)] and canine coronaviruses; Group 2 contains HuCoV-OC43 along with MHV (mouse hepatitis virus), bovine coronavirus and haemagglutinating encephalomyelitis virus; and Group 3...