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Keywords: coronary heart disease
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Clin Sci (Lond) (2019) 133 (2): 205–224.
Published: 22 January 2019
... 12 2018 02 01 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 coronary heart disease cardiovascular disease PCSK9 inhibitors There is now overwhelming evidence to support reducing low-density lipoprotein cholesterol...
Clin Sci (Lond) (2017) 131 (9): 833–846.
Published: 19 April 2017
...) and macrovascular [coronary heart disease (CHD), myocardial infarction, peripheral arterial disease (PAD) and stroke] disease are different in the two sexes. In general, men appear to be at a higher risk for diabetic microvascular complications, while the consequences of macrovascular complications may be greater...
Clin Sci (Lond) (2016) 130 (24): 2279–2293.
Published: 10 November 2016
...) expression in HUVECs. adhesion factor cardiac troponin I coronary heart disease endothelial cell myocardial ischaemia–reperfusion injury • For CHD, there are many classic risk factors in the development of atherosclerosis and coronary artery occlusion, like dislipidaemia and diabetes...
Includes: Supplementary data
Clin Sci (Lond) (2009) 116 (2): 87–98.
Published: 15 December 2008
... levels and CHD (coronary heart disease) risk. The cardioprotective effects of HDLs have been attributed to several mechanisms, including their involvement in the reverse cholesterol transport pathway. HDLs also have antioxidant, anti-inflammatory and antithrombotic properties and promote endothelial...
Clin Sci (Lond) (2009) 116 (1): 41–43.
Published: 28 November 2008
...Adam Mullan; Naveed Sattar The oxidation hypothesis for CHD (coronary heart disease) is attractive; however, the almost universal failure of antioxidant vitamin supplementation as a CVD (cardiovascular disease) risk modifier challenges the oxidation hypothesis, at least as a concept that easily...
Clin Sci (Lond) (2009) 116 (1): 53–60.
Published: 28 November 2008
...) oxidation and the risk of fatal or non-fatal coronary heart disease in a general population. This may be due to a true lack of association or insufficient power. Correspondence: Professor Mark Woodward (email mark.woodward@mountsinai.org ). 16 11 2007 12 5 2008 28 5 2008 28 5...
Clin Sci (Lond) (2007) 113 (11): 435–441.
Published: 01 November 2007
... with plasma lipid levels and CHD (coronary heart disease) in healthy U.K. men and patients with clinically defined definite FH (familial hypercholesterolaemia). Genotypes were determined using PCR and restriction enzyme digestion in 2444 healthy middle-aged (50–61 years) men from the prospective NPHSII...
Clin Sci (Lond) (2007) 112 (12): 617–624.
Published: 14 May 2007
...Philippa J. Talmud; David M. Flavell; Khaled Alfakih; Jackie A. Cooper; Anthony J. Balmforth; Mohan Sivananthan; Hugh E. Montgomery; Alistair S. Hall; Steve E. Humphries LVH [LV (left ventricular) hypertrophy] is an independent risk factor for CHD (coronary heart disease). During LVH, the preferred...
Clin Sci (Lond) (2006) 111 (5): 333–340.
Published: 13 October 2006
.... This prompted us to perform a case-control study to investigate the relationship of ACE2 polymorphisms with CHD (coronary heart disease) and MI (myocardial infarction). Three single nucleotide polymorphisms in the ACE2 gene (1075A/G, 8790A/G and 16854G/C) were genotyped by PCR-RFLP (restriction-fragment-length...
Clin Sci (Lond) (2006) 110 (3): 327–328.
Published: 10 February 2006
...Gordon D. O. Lowe Prospective epidemiological studies have shown associations of circulating inflammatory markers with risk of CHD (coronary heart disease); however, these associations are modest after adjustment for confounding by established risk factors, and do not add significantly...
Clin Sci (Lond) (2005) 109 (2): 171–176.
Published: 25 July 2005
...Hiren Divecha; Naveed Sattar; Ann Rumley; Lynne Cherry; Gordon D. O. Lowe; Roger Sturrock Men with AS (ankylosing spondylitis) are at elevated risk for CHD (coronary heart disease) but information on risk factors is sparse. We compared a range of conventional and novel risk factors in men...
Clin Sci (Lond) (2005) 108 (2): 129–135.
Published: 21 January 2005
...Altan ONAT; Bülent UZUNLAR; Gülay HERGENÇ; Mehmet YAZICI; Ibrahim SARI; Hüseyin UYAREL; Günay CAN; Vedat SANSOY In the present study, we examined (i) whether C3 (complement C3) was an independent marker of prevalent CHD (coronary heart disease), and (ii) which preferential associations existed...
Clin Sci (Lond) (2003) 104 (3): 323–327.
Published: 17 February 2003
...Sybille GRUSKA; Ingo JENDRAL; Rainer RETTIG; Günter KRAATZ The present study was designed to test the hypothesis that enhanced intracellular calcium signalling and increased sodium/lithium countertransport (Na + /Li + CT) activity may be associated with coronary heart disease (CHD) in non-diabetic...
Clin Sci (Lond) (2001) 101 (6): 659–670.
Published: 22 November 2001
...Jonathan VALABHJI; Avril J. McCOLL; Michael SCHACHTER; Surinder DHANJIL; William RICHMOND; Robert S. ELKELES Type I diabetes is associated with a high incidence of coronary heart disease (CHD), despite a normal or even increased concentration of high-density lipoprotein (HDL) cholesterol...
Clin Sci (Lond) (2000) 99 (3): 247–251.
Published: 23 August 2000
... have found the D allele to be associated with MI, coronary heart disease (CHD) or other cardiac pathology, while others have not. In the present study 713 consecutive patients, < 50 years of age, documented prospectively with angiographic CHD (> 50% diameter stenosis of at least one coronary...
Clin Sci (Lond) (1999) 97 (3): 269–276.
Published: 15 July 1999
... for coronary heart disease in the free-living population. While much of the atherogenicity of small, dense LDL is known to arise from its structural properties, the extent to which an increase in the number of small, dense LDL particles (hyper-apoprotein B) contributes to this risk of coronary heart disease...
Clin Sci (Lond) (1998) 95 (2): 115–128.
Published: 01 August 1998
...D. J. P. BARKER 1. Many human fetuses have to adapt to a limited supply of nutrients. In doing so they permanently change their structure and metabolism. 2. These ‘programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related...
Clin Sci (Lond) (1996) 91 (4): 399–413.
Published: 01 October 1996
... >5.5mmol/l who have coronary heart disease, other forms of atherosclerotic vascular disease, or who are free of vascular disease but have a risk of major coronary events ≥ 1.5% per year. Choice of an appropriate treatment policy will require (i) knowledge of the proportion of the population who will need...
Clin Sci (Lond) (1996) 90 (4): 243–253.
Published: 01 April 1996
...Keith N. Frayn; Christine M. Williams; Peter Arner © 1996 The Biochemical Society and the Medical Research Society 1996 coronary heart disease insulin resistance non-esterified fatty acids non-insulin-dependent diabetes obesity stress Clinical Science (1996) W, 243-253 (Printed...
Clin Sci (Lond) (1995) 89 (4): 333–342.
Published: 01 October 1995
...Dilys J. Freeman; Chris J. Packard © 1995 The Biochemical Society and the Medical Research Society 1995 coronary heart disease lipoprotein metabolism smoking triacylgycerol Clinical Science (1995) 89, 333--342 (Printed in Great Britain) Editorial Review Smoking and plasma lipoprotein...
Clin Sci (Lond) (1992) 82 (1): 1–8.
Published: 01 January 1992
...Keith N. Frayn; Simon W. Coppack © 1992 The Biochemical Society and the Medical Research Society 1992 adipose tissue coronary heart disease insulin insulin resistance lipoproteins non-esterified fatty acids triacylglycerol Clinical Science (1992) 82, 1-8 (Printed in Great Britain...
Clin Sci Mol Med (1978) 55 (s4): 325s–328s.
Published: 01 December 1978
... risk for coronary heart disease which could offset partly the beneficial effects of a lowered blood pressure in diuretic-treated patients with hypertension. © 1978 The Biochemical Society and the Medical Research Society 1978 coronary heart disease diuretics lipids α-lipoproteins β...
Clin Sci Mol Med (1976) 51 (s3): 661s–663s.
Published: 01 December 1976
... coronary heart disease cerebrovascular disease epidemiology hypertension occupation socio-economic © 1976 The Biochemical Society and the Medical Research Society 1976 Clinical Science and Molecular Medicine (1 976) 51, 661~663s. Alcohol use, hypertension and coronary heart disease J . D...
Clin Sci Mol Med (1976) 51 (5): 475–482.
Published: 01 November 1976
... simply estimated from the plasma HDL cholesterol concentration than from a con- sideration of other major lipid risk factors and blood pressure. Key words : blood pressure, cholesterol, coronary heart disease, exercise test, high-density lipoprotein, low-density lipoprotein. Introduction Coronary heart...
Clin Sci Mol Med (1973) 45 (s1): 107s–110s.
Published: 01 August 1973
... only after 45 years of age. 3. In contrast to this, weight gain influences both pressures positively regardless of age. © 1994 The Biochemical Society and the Medical Research Society 1994 blood pressure age body weight coronary heart disease distribution curves male steelmill Clinical...