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Keywords: cognitive impairment
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Clin Sci (Lond) (2018) 132 (10): 1021–1038.
Published: 25 May 2018
..., including cognition, memory, anxiety and depression, and several neurological disorders. Overactivity of the pressor axis of the RAS has been implicated in stroke and several brain disorders, such as cognitive impairment, dementia, and Alzheimer or Parkinson’s disease. The present review is focused...
Clin Sci (Lond) (2017) 131 (19): 2451–2468.
Published: 28 September 2017
...Jessica Duncombe; Akihiro Kitamura; Yoshiki Hase; Masafumi Ihara; Raj N. Kalaria; Karen Horsburgh Increasing evidence suggests that vascular risk factors contribute to neurodegeneration, cognitive impairment and dementia. While there is considerable overlap between features of vascular cognitive...
Clin Sci (Lond) (2017) 131 (15): 1895–1904.
Published: 07 July 2017
...-related cognitive impairment participated in the study. We measured plasma GDF-11 and β2-MG levels using ELISA and immunoturbidimetry, respectively. The results were statistically analyzed to evaluate the associations between levels of GDF-11 and β2-MG, and ageing and cognitive impairments. Circulating...
Clin Sci (Lond) (2017) 131 (14): 1561–1578.
Published: 30 June 2017
... vascular risk factors–diabetes, hypercholesterolaemia, hypertension and smoking–are implicated as risk factors for VaD. The associations between cholesterol and small vessel disease (SVD), stroke, cognitive impairment and subsequent dementia are complex and as yet not fully understood. Similarly...
Clin Sci (Lond) (2017) 131 (13): 1495–1498.
Published: 28 June 2017
...Eve Miller-Hodges; Neeraj Dhaun Chronic kidney disease (CKD) is common, its prevalence increasing with age. Cognitive impairment is common in the elderly, in CKD and in those on maintenance haemodialysis. As cognitive impairment is the precursor to dementia, the identification of reversible risk...
Clin Sci (Lond) (2016) 130 (20): 1807–1822.
Published: 15 September 2016
...Trevor Hardigan; Rebecca Ward; Adviye Ergul The incidence of diabetes has more than doubled in the United States in the last 30 years and the global disease rate is projected to double by 2030. Cognitive impairment has been associated with diabetes, worsening quality of life in patients...
Clin Sci (Lond) (2016) 130 (4): 221–238.
Published: 14 January 2016
... literature on the role of the renin-angiotensin system in neurovascular disorders including stroke, retinopathy, traumatic brain injury and cognitive impairment. The review presents both experimental and clinical studies conducted in the field, and sheds light on the translational gap and clinical...