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Keywords: clonal haematopoiesis of indeterminate potentialClose
Leanne Mooney, Carl S. Goodyear, Tamir Chandra, Kristina Kirschner, Mhairi Copland, Mark C. Petrie, Ninian N. Lang
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (7): 991–1007.
Published: 16 April 2021
... is important, recent evidence highlights clonal haematopoiesis of indeterminant potential (CHIP) as a further key risk factor. CHIP reflects the accumulation of somatic, potentially pro-leukaemic gene mutations within haematopoietic stem cells over time. The most common mutations associated with CHIP and CVD...