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Keywords: cigarette smoke
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Articles
Clin Sci (Lond) (2022) 136 (8): 537–555.
Published: 21 April 2022
... exacerbate pulmonary and/or cardiovascular complications, increasing their likelihood of death. The mechanisms driving these complications remain unknown but increased oxidative stress has been implicated. Here we investigated whether influenza A virus (IAV) infection, following chronic cigarette smoke (CS...
Articles
Clin Sci (Lond) (2022) 136 (6): 405–423.
Published: 23 March 2022
...Kurt Brassington; Stavros Selemidis; Steven Bozinovski; Ross Vlahos Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible diseases, that share a number of common causative factors including cigarette smoking. Atherosclerosis drastically impairs blood flow...
Articles
Clin Sci (Lond) (2019) 133 (7): 885–904.
Published: 12 April 2019
... for an increased effect of ICS in COPD patients with higher blood eosinophil counts remains unknown. chronic obstructive pulmonary disease cigarette smoke cardiovascular disease lung inflammation oxidative stress vascular dysfunction Figure 3 Blood vessel homoeostasis The role of NO synthase...
Articles
Clin Sci (Lond) (2019) 133 (4): 551–564.
Published: 18 February 2019
... that an exaggerated inflammatory and oxidative stress response to cigarette smoke (CS) leads to, emphysema, small airway fibrosis, mucus hypersecretion, and progressive airflow limitation. Current treatments have limited efficacy in inhibiting chronic inflammation and consequently do not reverse the pathology...
Articles
Clin Sci (Lond) (2018) 132 (4): 475–488.
Published: 28 February 2018
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cigarette smoke DNA double strand breaks lung carcinogenesis thirdhand smoke Recently a new type of tobacco exposure...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (19): 2409–2426.
Published: 15 September 2017
... and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . Oxidative Stress Hormone imbalance Inflammatory Cytokines Cigarette smoke response to injury Cigarette toxins affect biological processes as well as organ systems and are detrimental to human health [ 1 , 2...
Articles
Clin Sci (Lond) (2015) 129 (9): 785–796.
Published: 05 August 2015
...Steven Bozinovski; Huei Jiunn Seow; Sheau Pyng Jamie Chan; Desiree Anthony; Jonathan McQualter; Michelle Hansen; Brendan J. Jenkins; Gary P. Anderson; Ross Vlahos Cigarette smoke (CS) is the major cause of chronic obstructive pulmonary disease (COPD). Interleukin-17A (IL-17A) is a pivotal cytokine...
Articles
Clin Sci (Lond) (1995) 88 (3): 337–344.
Published: 01 March 1995
...Shunsuke Shoji; Ronald F. Ertl; Sekiya Koyama; Richard Robbins; George Leikauf; Susanna Von Essen; Stephen I. Rennard 1. Recruitment of neutrophils into the airway is a prominent feature of chronic bronchitis, a syndrome often associated with exposure to cigarette smoke. Since bronchial epithelial...
Articles
Clin Sci (Lond) (1987) 72 (5): 629–637.
Published: 01 May 1987
...D. F. Rogers; N. C. Turner; C. Marriott; P. K. Jeffery 1. Mucous secretion and mucosal permeability by the larynx and trachea, isolated in situ , was investigated in normal rats and in those in which ‘chronic bronchitis' was induced by daily exposure to cigarette smoke for 2 weeks. Fucose was used...
Articles
Clin Sci (Lond) (1986) 71 (2): 179–187.
Published: 01 August 1986
.... Subsequently, changes in output of radiolabelled macromolecules were used to indicate changes in mucin secretion rate. 2. Cigarette smoke, diluted to 10% by volume, was passed through the larynx or through the tracheal segment, or given into the lower airway. Control insufflations of air were given by the same...
Articles
Clin Sci (Lond) (1986) 70 (5): 427–433.
Published: 01 May 1986
...D. F. Rogers; Deborah A. Williams; P. K. Jeffery 1. Nicotine is of interest as a major constituent of cigarette smoke and as an additive to chewing gum used to help patients to stop smoking. 2. Specific pathogen-free rats were given an aerosol or injections of nicotine hydrogen (+) tartrate ( l...
Articles
Clin Sci (Lond) (1981) 61 (1): 85–90.
Published: 01 July 1981
... smaller and less consistent. Similar effects were observed with intermittent inhalations of charcoal. 3. In four subjects the tidal volume response was significantly decreased by oropharyngeal and laryngeal anaesthesia with lignocaine. 4. Filtration of particulate matter from the cigarette smoke delayed...