... values for the PCR production were analyzed and quantified. The primer sequences of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and β-actin are shown in our previous study [ 29 , 30 ]. Cancer Cardiotoxicity Chemotherapy Doxorubicin Mitochondria Mitochondrial dynamics...

... of cancer treatments. Therefore, numerous preclinical studies demonstrate that inhibition of CYP1B1 protects against chemotherapy-induced cardiotoxicity and prevents chemo- and radio-resistance. Most of these studies have utilized phytochemicals to inhibit CYP1B1. Since phytochemicals have multiple targets...

...-oncology cardiotoxicity chemotherapy heart failure PI3Kα In response to pressure overload, p110α (PI3Kα’s catalytic subunit) will translocate to intercalated discs, which are involved in sensing biomechanical stress in heart tissue [ 18 ]. Transgenic mice lacking p110α activity demonstrated...

... ( zhangpeng2600@163.com ) * These authors contributed equally to this work. 22 08 2019 24 12 2019 14 01 2020 14 01 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 apoptosis Bim chemotherapy colorectal cancer SPZ1...

... ]. 1 6 2016 17 10 2016 3 11 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 cardio-oncology chemotherapy heart failure In Canada, for example, there are an estimated 810 045 cancer survivors, and this number...

...Robert C. RINTOUL; Tariq SETHI Tumour recurrence following chemotherapy remains a major obstacle to the cure of many cancers. This is exemplified by small-cell lung cancer (SCLC). Host-tumour interactions are central to tumour survival and proliferation. We hypothesized that a factor(s) within...

...D. M. K. Keefe; A. G. Cummins; B. M. Dale; D. Kotasek; T. A. Robb; R. E. Sage 1. Mucositis is a common side-effect of chemotherapy which is difficult to assess except by invasive means such as upper gastrointestinal endoscopy. Differential absorption of mono- and di-saccharides, such as rhamnose...

... pressure in hypertensive individuals, and the results suggest that DLIF may contribute to the increased blood pressure in some of these subjects. 26 4 1989 3 5 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 chemotherapy fluid retention hypertension (Na...

... leukaemia and one patient with chronic myeloid leukaemia before and after chemotherapy. 2. Gas chromatography-mass spectrometry was used to determine plasma [ 15 N]glycine enrichment. Pool sizes and turnover rate constants were estimated from time-decay curves for isotope enrichment. 3. Turnover rate...

... of these compounds, which were released in association with liposomal lipid, in draining lymph nodes. 27 11 1974 © 1975 The Biochemical Society and the Medical Research Society 1975 chemotherapy drug therapy liposomes Clinical Science and Molecular Medicine (1975) 49 99-106. Liposomes...