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Keywords: cell cycle
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Articles
Clin Sci (Lond) (2022) 136 (12): 911–934.
Published: 20 June 2022
...Donya Mahiny-Shahmohammady; Ludger Hauck; Filio Billia Shortly after birth, mammalian cardiomyocytes (CM) exit the cell cycle and cease to proliferate. The inability of adult CM to replicate renders the heart particularly vulnerable to injury. Restoration of CM proliferation would be an attractive...
Articles
Clin Sci (Lond) (2019) 133 (15): 1745–1758.
Published: 07 August 2019
... motility of BCa cells via affecting epithelial–mesenchymal transition (EMT)-related proteins. Furthermore, etomoxir induced BCa cell cycle arrest at G 0 /G 1 phase through peroxisome proliferator-activated receptor (PPAR) γ-mediated pathway with alterations in fatty acid metabolism associated gene...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (11): 1229–1253.
Published: 07 June 2019
... review the relevant literature since September 2015 concluding that it remains a challenge to verify that a therapy induces indeed cardiomyocyte proliferation. Most importantly, it is unclear that the detected increase in cardiomyocyte cell cycle activity is required for an associated improved function...
Articles
Clin Sci (Lond) (2019) 133 (3): 425–441.
Published: 05 February 2019
...Yinlan Hu; Guoqing Jin; Bing Li; Yanmei Chen; Lintao Zhong; Guojun Chen; Xiaoqiang Chen; Jiayuan Zhong; Wangjun Liao; Yulin Liao; Yuegang Wang; Jianping Bin MiRNAs regulate the cardiomyocyte (CM) cell cycle at the post-transcriptional level, affect cell proliferation, and intervene in harmed CM...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (2): 105–111.
Published: 14 December 2016
...Chayki Charar; Yosef Gruenbaum Lamins are nuclear intermediate filaments (IFs) with important roles in most nuclear activities, including nuclear organization and cell-cycle progression. Mutations in human lamins cause over 17 different diseases, termed laminopathies. Most of these diseases...
Articles
Clin Sci (Lond) (2008) 114 (1): 27–35.
Published: 30 November 2007
... cycle inhibitor p27 [ 9 ], whereas others have found up-regulation of p21 [ 10 ]. Further findings supporting the capability of Mg to influence the cell cycle were obtained by DNA expression profiling (RNA arrays). It was found ([ 11 ], and F. I. Wolf, V. Trapani, M. Simonacci, A. Boninsegna, A. Mazur...
Articles
Clin Sci (Lond) (2008) 114 (1): 73–83.
Published: 30 November 2007
... with FTS intraperitoneally (1, 8 and 16 h after PH) and killed 12, 24 and 48 h after PH. Cell proliferation, phosphorlyation of members of the MAPK (mitogen-activated protein kinase) pathway and levels and activity of cell cycle effectors (cyclin D, cyclin E, Cdk2 and Cdk4) were assessed in FTS-treated...
Articles
Clin Sci (Lond) (1995) 88 (2): 119–130.
Published: 01 February 1995
...Ralph A. Boulton; Humphrey J. F. Hodgson © 1995 The Biochemical Society and the Medical Research Society 1995 5-bromodeoxyuridine cell cycle flow cytometry Ki-67 polyamine proliferating cell nuclear antigen proliferation thymidine Clinical Science (1995) 88, 119-130 (Printed...