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Keywords: cardiotoxicity
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Clin Sci (Lond) (2021) 135 (10): 1311–1332.
Published: 28 May 2021
... anthracycline-induced cardiomyopathy. This review details the established and emerging data regarding the molecular mechanisms of anthracycline-induced cardiovascular toxicity. Increased oxidative stress is another important mechanism of anthracycline cardiotoxicity [ 32 ]. ROS are natural byproducts...
Includes: Supplementary data
Clin Sci (Lond) (2020) 134 (19): 2595–2622.
Published: 14 October 2020
... clinical implications of treating patients with these drugs, such as increased arrhythmia burden, biventricular cardiac dysfunction, and impaired recovery from cardiotoxicity. Recommendations for future directions for preclinical and clinical work are made, highlighting the possible role of PI3Kα...
Clin Sci (Lond) (2020) 134 (13): 1859–1885.
Published: 17 July 2020
...Keith Dadson; Oscar Calvillo-Argüelles; Paaladinesh Thavendiranathan; Filio Billia Despite the known risk of cardiotoxicity, anthracyclines are widely prescribed chemotherapeutic agents. They are broadly characterized as being a robust effector of cellular apoptosis in rapidly proliferating cells...