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Keywords: cardiomyocyte proliferation
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Clin Sci (Lond) (2022) 136 (12): 911–934.
Published: 20 June 2022
... to new diploid mononucleate CM as well as polyploid and multinucleated CM. In contrast, the contribution of resident stem/progenitor cells to adult CM homeostasis is very low at baseline and post-MI [ 67–69 ]. cardiomyocyte proliferation cell cycle cyclin dependent kinases microRNA regeneration...
Clin Sci (Lond) (2017) 131 (24): 2919–2932.
Published: 08 December 2017
.... Meanwhile, CGX1321 increased Ki67 + and phosphohistone H3 (PH3 + ) cardiomyocytes in culture, indicating enhanced cardiomyocyte proliferation. The mRNA microarray showed that CGX1321 up-regulated cell cycle regulating genes such as Ccnb1 and Ccne1 . CGX1321 did not alter YAP protein phosphorylation...
Includes: Supplementary data