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Keywords: cardiomyocyte
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Clin Sci (Lond) (2017) 131 (13): 1375–1392.
Published: 23 June 2017
... the mutation rate is low, and screens have failed to detect PLN mutations [ 39 , 40 ]. arrhythmogenic right ventricular (ARVC) cardiomyocyte cardiomyopathy dilated cardiomyopathy (DCM) heart failure hypertrophic cardiomyopathy (HCM) hypertrophy primary cardiomyopathy restrictive cardiomyopathy...
Clin Sci (Lond) (2015) 128 (7): 387–403.
Published: 09 December 2014
...-dependent autophagy plays an important role in the elimination of pathogens by phagocytes and in the regulation of vascular- and cancer-cell survival. Interestingly, we recently found that Nox is also important for autophagy regulation in cardiomyocytes. We found that Nox4, but not Nox2, promotes...
Clin Sci (Lond) (2014) 127 (12): 665–677.
Published: 08 August 2014
... and adipose tissues. The aim of the present study was to assess the role of NOD1 in the progression of diabetic cardiomyopathy. We have measured NOD1 protein in cardiac tissue from Type 2 diabetic ( db ) mice. Heart and isolated cardiomyocytes from db mice revealed a significant increase in NOD1, together...
Includes: Supplementary data
Clin Sci (Lond) (2011) 121 (8): 315–329.
Published: 24 June 2011
... old. Genetic variations and molecular adaptations are the primary contributors to the onset of cardiovascular disease; however, molecular links between age and heart syndromes are complex and involve much more than the passage of time. Changes in CM (cardiomyocyte) structure and function occur...
Clin Sci (Lond) (2011) 121 (7): 305–312.
Published: 07 June 2011
... in cardiomyocytes through increased inflammatory cytokines and oxidative stress [ 7 ]. Therefore PPARs play a critical role in the pathogenesis of diabetic cardiomyopathy. Hypertension is an important cause of cardiovascular morbidity and mortality [ 8 ]. Decreased expression of PPAR-α protein was found...
Clin Sci (Lond) (2002) 103 (2): 191–200.
Published: 17 July 2002
... of synchronous beating, bradycardia and cessation of contraction in cultured rat cardiomyocytes [Williamson, Gorelik, Eaton, Lab, de Swiet and Korchev (2001) Clin. Sci. 100 , 363–369]. The aim of the present study was to investigate the effect of taurocholate on cardiomyocytes further. We demonstrated a reduced...
Clin Sci (Lond) (2000) 98 (4): 401–407.
Published: 08 March 2000
...Leanne M. D. DELBRIDGE; Pamela J. CONNELL; Peter J. HARRIS; Trefor O. MORGAN Little is known about the direct cardiac effects of socially common sub-intoxication levels of ethanol. Previous studies evaluating the responses of normal cardiomyocytes to short-term ethanol exposure have utilized...