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Keywords: cardiac fibrosis
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Clin Sci (Lond) (2021) 135 (11): 1409–1426.
Published: 04 June 2021
...Chenliang Ge; Yang Cheng; Yihao Fan; Yan He Vincristine (VCR) is widely used in cancer therapies, although its benefits on cardiac fibrosis remain unknown. Here, we investigated VCR’s efficacy on cardiac fibrosis and elucidated the underlying mechanism of action. Network pharmacology was employed...
Includes: Supplementary data
Clin Sci (Lond) (2019) 133 (22): 2329–2344.
Published: 28 November 2019
... Press Limited on behalf of the Biochemical Society 2019 adipokines brown adipose tissue cardiac fibrosis cardiac hypertrophy cardiovascular disease obesity Adipose tissue biology is intricately linked to cardiovascular health, and the growing obesity epidemic increases the prevalence...
Clin Sci (Lond) (2019) 133 (17): 1845–1856.
Published: 10 September 2019
...Kun Yang; Jiaran Shi; Zhujun Hu; Xiaosheng Hu Cardiac fibrosis is a common pathological feature of many cardiovascular diseases. The regulatory mechanisms of miRNAs in cardiac fibrosis are still unknown. Previous studies on miR-214-3p in cardiac fibroblasts reached contradictory conclusions. Thus...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (10): 897–915.
Published: 04 May 2017
...@baker.edu.au ) 7 12 2016 2 2 2017 3 2 2017 © 2017 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2017 cardiac fibrosis cardiomyocyte hypertrophy diabetic cardiomyopathy diastolic dysfunction hyperglycaemia The global incidence...
Clin Sci (Lond) (2009) 116 (9): 731–739.
Published: 02 April 2009
...Peter Wilson; James Morgan; John W. Funder; Peter J. Fuller; Morag J. Young Coronary, vascular and perivascular inflammation in rats following MR (mineralocorticoid receptor) activation plus salt are well-characterized precursors for the appearance of cardiac fibrosis. Endogenous corticosterone...
Clin Sci (Lond) (2007) 112 (9): 467–475.
Published: 02 April 2007
... stages of the development of cardiac fibrosis in experimental animals. These studies suggest potential mechanisms for the benefits observed in recent large scale clinical trials investigating the cardioprotective effects of MR antagonists given in conjunction with current best practice therapy...