Skip Nav Destination
1-3 of 3
Clin Sci (Lond) (2023) 137 (15): 1209.
Published: 16 August 2023
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . airway remodelling asthma biologics chronic rhinosinusitis precision medicine type 2 inflammation ...
Ilja Striz, Kornel Golebski, Zuzana Strizova, Stelios Loukides, Petros Bakakos, Nicola A. Hanania, Milos Jesenak, Zuzana Diamant
Clin Sci (Lond) (2023) 137 (9): 727–753.
Published: 18 May 2023
... of targeted biologics has shown clinical efficacy in patients with refractory T2 airway inflammation, including anti-IgE (omalizumab), anti-IL-5 (mepolizumab, reslizumab)/anti-IL5R (benralizumab), anti-IL-4R-α (anti-IL-4/IL-13, dupilumab), and anti-TSLP (tezepelumab). In non-type-2 endotypes, no targeted...
Clin Sci (Lond) (2014) 126 (9): 593–612.
Published: 14 January 2014
... immunity biologics TRAIL (TNF-related apoptosis-inducing ligand; TNSF10) is a member of TNF family expressed by most cells as CD253 which, after proteolytic cleavage from the membrane, forms a soluble cytokine selectively cytotoxic in inducing apoptosis in tumour cells with minimal...