... remaining constant for carbachol in explants maintained for up to 48h. The possibility that this was caused by changes in ET receptor density was assessed using light microscopic quantitative autoradiography. In view of the increased responsiveness to ET-1 in cultured explants, it was surprising...

..., BQ788, to identify the receptor subtype functionally involved. Overall inhibition of [ 125 I]ET-1 binding by Naf was assessed using autoradiography. Identification of receptor-subtype binding reduction was assessed using the radioligands [ 125 I]PD151242 and [ 125 I]BQ3020. Naf inhibited ET-1-mediated...

... that semicarbazide-sensitive amine oxidase in blood plasma may originate, at least in part, from the skeleton. Correspondence: Dr Jonas Ekblom, Molecular Biology, 6 1 1999 5 3 1999 9 4 1999 The Biochemical Society and the Medical Research Society © 1999 1999 autoradiography...

... in vivo in man and experimental animals use haemodynamic measurements plus assessment of diuresis and natriuresis and urinary/plasma ANP and cyclic GMP as indicators that NEP has been inhibited after administration of an NEP inhibitor. Key words: autoradiography, '251-labelled RB 104, neutral...

...R. J. Summers; J. A. Stephenson; S. Lipe; C. B. Neylon 1. The location of α 2 -adrenoceptors has been examined in slide-mounted sections of dog kidney by using labelling in vitro with [ 3 H]rauwolscine and autoradiography. 2. [ 3 H]Rauwolscine binding in dog kidney was of high affinity, saturable...