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Keywords: antagonist
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Clin Sci (Lond) (2022) 136 (21): 1513–1533.
Published: 03 November 2022
... as an antagonist as well. In this perspective/opinion piece, we try to resolve the ambiguity that surrounds the efficacy of this compound by extensively reviewing the literature, tracing its beginnings to 1989, showing that CGP42112 has never been convincingly shown to be a partial agonist or an antagonist...
Includes: Supplementary data
Clin Sci (Lond) (2003) 105 (1): 1–8.
Published: 01 July 2003
...James Walter FERGUSON; George THERAPONDOS; David E NEWBY; Peter Clive HAYES Correspondence: Dr James Walter Ferguson (e-mail j.w.ferguson@ed.ac.uk ). 7 2 2003 13 3 2003 14 3 2003 14 3 2003 © 2003 The Biochemical Society 2003 antagonist aquaporin aquaretic...
Clin Sci (Lond) (2002) 103 (s2002): 380S–384S.
Published: 01 September 2002
... was fed with normal food with tap water (NS). The antagonists tested were the ET A receptor antagonist BQ-123 (1 and 5mg/kg), the ET B receptor antagonist BQ-788 (0.25 and 1mg/kg), the angiotensin receptor type 1 antagonist losartan (10mg/kg) and the angiotensin-converting enzyme inhibitor captopril (3mg...
Clin Sci (Lond) (2001) 100 (4): 359–362.
Published: 26 February 2001
... that therapeutic antagonism of these pathways is imminently achievable. antagonist basophil chemokine eosiniphil inflammation receptor Correspondence : Dr Ian Sabroe (e-mail i.sabroe@ic.ac.uk ). * This paper was presented at the Glaxo/MRS Young Investigator session at the MRS Meeting, Royal...
Clin Sci (Lond) (1996) 91 (5): 627–631.
Published: 01 November 1996
...Steven M. Frank; Nader El-Gamal; Srinivasa N. Raja; Peter K. Wu 1. Previous studies on the thermoregulatory effects of α-adrenoceptor antagonists have been performed primarily in animals and the findings have been inconsistent. There is evidence for thermoregulatory impairment by α-adrenergic...
Clin Sci (Lond) (1995) 89 (3): 219–225.
Published: 01 September 1995
...Steven M. Frank; Nader El-Gamal; Srinivasa N. Raja; Peter K. Wu; Osama Afifi 1. Although α-adrenoceptor antagonists have been shown to induce core hypothermia in animals, it is unclear whether the primary mechanism is increased heat loss or decreased heat production. Furthermore, studies have...
Clin Sci Mol Med (1976) 51 (1): 41–45.
Published: 01 July 1976
... as potent as Asp 1 -angiotensin II in elevating blood pressure but its aldosterone-stimulating activity was not higher than that of the naturally occurring peptide. 3. A specific competitive antagonist of angiotensin II, Sar 1 -Ile 8 -angiotensin II, blocked the pressor but not the aldosterone-stimulating...