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Keywords: angiotensin converting enzyme 2
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Coronavirus
Clin Sci (Lond) (2021) 135 (15): 1805–1824.
Published: 02 August 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . angiotensin converting enzyme 2 cardiovascular disease COVID-19 placental biology pregnancy SARS-COV-2 The world is facing one of the greatest pandemics in history. The coronavirus disease 2019...
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Clin Sci (Lond) (2021) 135 (7): 911–924.
Published: 12 April 2021
... at a concentration of 5 mg/ml, which was given ad libitum for the duration of 5 days [ 20 ]. 20 11 2020 23 03 2021 29 03 2021 30 03 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 angiotensin converting enzyme 2 Blood...
Includes: Supplementary data
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Clin Sci (Lond) (2021) 135 (6): 775–791.
Published: 17 March 2021
... therefore hypothesized that another metabolic pathway of brain angiotensin II, such as the conversion of angiotensin II into angiotensin 1-7 (Ang 1-7) by angiotensin-converting enzyme 2 (ACE2) might be activated following brain APA inhibition. We found that the intracerebroventricular (icv) administration...
Includes: Supplementary data
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Clin Sci (Lond) (2021) 135 (2): 387–407.
Published: 29 January 2021
... increased Ang-(1-7)/Mas1 signalling [ 57 ]. angiotensin converting enzyme 2 COVID-19 endothelial cells vascular smooth muscle The renin–angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, electrolyte and water homeostasis, vascular tone and cardiovascular...
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Clin Sci (Lond) (2020) 134 (23): 3229–3232.
Published: 11 December 2020
...Michael Bader; Anthony J. Turner; Natalia Alenina This Editorial, written by Guest Editors Professor Michael Bader, Professor Anthony J. Turner and Dr Natalia Alenina, proudly introduces the Clinical Science -themed collection on angiotensin-converting enzyme 2 (ACE2), a multifunctional protein...
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Clin Sci (Lond) (2020) 134 (23): 3137–3158.
Published: 07 December 2020
...Fiona J. Warner; Harinda Rajapaksha; Nicholas Shackel; Chandana B. Herath Twenty years ago, the discovery of angiotensin-converting enzyme 2 (ACE2) was an important breakthrough dramatically enhancing our understanding of the renin–angiotensin system (RAS). The classical RAS is driven by its key...
Articles
Clin Sci (Lond) (2020) 134 (23): 3063–3078.
Published: 02 December 2020
...Thiago Verano-Braga; Ana Luiza Valle Martins; Daisy Motta-Santos; Maria José Campagnole-Santos; Robson Augusto Souza Santos In 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we see the renin...
Articles
Clin Sci (Lond) (2020) 134 (22): 3047–3062.
Published: 24 November 2020
...Koichi Yamamoto; Hikari Takeshita; Hiromi Rakugi Angiotensin converting enzyme-2 (ACE2) is a multifunctional transmembrane protein recently recognised as the entry receptor of the virus causing COVID-19. In the renin–angiotensin system (RAS), ACE2 cleaves angiotensin II (Ang II) into angiotensin 1...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2020) 134 (22): 2987–3006.
Published: 19 November 2020
... revived interest and research in this area, resulting in thousands of publications during the past 11 months. angiotensin converting enzyme 2 AT2 receptor COVID-19 inflammation © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf...
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Clin Sci (Lond) (2020) 134 (21): 2823–2833.
Published: 03 November 2020
... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 amino acid transporters angiotensin converting enzyme 2 kidney tubule small intestine ACE2 is expressed in a wide variety of human tissues with highest levels found in small intestine, kidney...
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Clin Sci (Lond) (2020) 134 (21): 2791–2805.
Published: 02 November 2020
... ) 04 09 2020 14 10 2020 16 10 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 angiotensin converting enzyme 2 COVID-19 renin-angiotensin system SARS-CoV-2 Several studies showed up-regulation of ACE2...
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Clin Sci (Lond) (2020) 134 (18): 2489–2501.
Published: 29 September 2020
... against pressure overload-induced cardiac hypertrophy [ 30 ]. 17 07 2020 12 09 2020 15 09 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 angiotensin converting enzyme 2 coronavirus COVID-19 metalloproteases renin...
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Clin Sci (Lond) (2020) 134 (17): 2319–2336.
Published: 09 September 2020
...) by promoting angiotensin converting enzyme 2 ( ACE2 ) transcription leading to increased ACE2 protein and activity while also antagonizing the effects of angiotensin II (Ang II). Apelin modulation of the RAS by increasing ACE2 action is limited due to its rapid degradation by proteases, including ACE2...
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Clin Sci (Lond) (2019) 133 (1): 55–74.
Published: 08 January 2019
... ( mchappel@wakehealth.edu ) 03 08 2018 20 11 2018 03 12 2018 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 angiotensin converting enzyme 2 angiotensin-(1-7) ACE fetal programming Cardiovascular disease including its...
Includes: Supplementary data