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Keywords: airway smooth muscle
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Clin Sci (Lond) (2018) 132 (3): 327–338.
Published: 02 February 2018
... study investigated the separate and combined effects of increased airway smooth muscle (ASM) layer thickness and allergy on AHR. We integrated a protocol of ovalbumin (OVA)-induced allergy into a non-inflammatory mouse model of ASM remodelling induced by conditional and airway-specific expression...
Clin Sci (Lond) (2005) 108 (6): 463–477.
Published: 24 May 2005
...Tony R. BAI; Darryl A. KNIGHT Structural changes reported in the airways of asthmatics include epithelial fragility, goblet cell hyperplasia, enlarged submucosal mucus glands, angiogenesis, increased matrix deposition in the airway wall, increased airway smooth muscle mass, wall thickening...
Clin Sci (Lond) (2002) 103 (s2002): 345S–348S.
Published: 01 September 2002
... and maximum response to carbachol and ET-1 was not altered in tissue from day 4 post-inoculation compared with the control. There seems to be a significant functional reserve for both receptor subtypes in this species that buffers the impact of P-3 infection on airway smooth muscle responsiveness to ET-1...
Clin Sci (Lond) (2002) 103 (2): 201–211.
Published: 17 July 2002
..., the only difference we observed was that, in asthma, the airway smooth muscle (ASM) was infiltrated by mast cells, suggesting that airway obstruction and AHR are due to an ASM mast cell myositis. This observation emphasizes that the features that characterize asthma, as opposed to bronchitis, are due...
Clin Sci (Lond) (1994) 86 (6): 647–652.
Published: 01 June 1994
...Alan J. Knox © 1994 The Biochemical Society and the Medical Research Society 1994 airway smooth muscle asthma Clinical Science (1994) 86, 64Y-652 (Printed in Great Britain) Editorial Review MY Airway remodelling in asthma: role of airway smooth muscle Alan J. KNOX Respiratory Medicine...