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Keywords: adipocytes
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Articles
Clin Sci (Lond) (2020) 134 (8): 1031–1048.
Published: 27 April 2020
...Marianna Santopaolo; Yue Gu; Gaia Spinetti; Paolo Madeddu Global trends in the prevalence of overweight and obesity put the adipocyte in the focus of huge medical interest. This review highlights a new topic in adipose tissue biology, namely the emerging pathogenic role of fat accumulation in bone...
Articles
Clin Sci (Lond) (2020) 134 (2): 315–330.
Published: 30 January 2020
... including mature adipocytes, immune cells, endothelial cells and progenitor cells gradually senesce at different levels in different fat depots with ageing and obesity, highlighting the heterogeneity and complexity of adipose tissue senescence. In this review, we discuss the causes and consequences...
Articles
Clin Sci (Lond) (2019) 133 (22): 2317–2327.
Published: 26 November 2019
... will be discussed, followed by novel secreted adipocyte-specific factors that show therapeutic promise in regulating the adipose–pancreatic β cell axis. Table 1 Summary of the effects of adipokines on pancreatic β cells Adipokines In vitro In vivo Clinical Leptin Inhibition of insulin...
Articles
Clin Sci (Lond) (2019) 133 (1): 23–40.
Published: 03 January 2019
... (WAT) dysfunction. Enlargement of WAT is associated with a transcriptional alteration of coding and non-coding RNAs (ncRNAs). For many years, big efforts have focused on understanding protein-coding RNAs and their involvement in the regulation of adipocyte physiology and subsequent role in obesity...
Articles
Articles
Clin Sci (Lond) (2017) 131 (13): 1529–1540.
Published: 28 June 2017
...-inflammatory adipokines in PE and healthy pregnancy. Subcutaneous and visceral adipose tissue biopsies were collected from healthy ( n =13) and PE ( n =13) mothers. Basal and lipopolysaccharide (LPS) stimulated adipocyte TNFα, IL-6, CCL-2, and CRP release was measured. Adipose tissue cell densities...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2016) 130 (18): 1603–1614.
Published: 08 August 2016
... (email bluma@medizin.uni-leipzig.de ). 14 1 2016 31 5 2016 2 6 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 adipocytes adipokines adipose tissue inflammation adipose tissue macrophages insulin resistance...
Articles
Clin Sci (Lond) (1984) 67 (1): 139–142.
Published: 01 July 1984
...Roy Taylor; Steven J. Proctor; Oliver James; Frederick Clark; K. George M. M. Alberti 1. The assumption that insulin binding to monocytes reflects that of insulin binding to adipocytes has been examined. 2. In normal, diabetic, thyrotoxic and cirrhotic subjects no correlation was observed between...
Articles
Clin Sci Mol Med (1975) 49 (1): 27–32.
Published: 01 July 1975
... before and after an oral glucose load (100 g). 2. Adipose tissue metabolites expressed as nmol/g wet weight correlated inversely with adipocyte diameter. 3. After fasting, fructose diphosphate and glycerol phosphate in adipose tissue decreased significantly. 4. The basal concentrations of metabolites...