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Keywords: acute pancreatitis
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Articles

Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis

Ning Hu, Xiaoyi Zhang, Xuanzhe Zhang, Yongjun Guan, Ruyuan He, Enfu Xue, Xiaoyi Zhang, Wenhong Deng, Jia Yu, Weixing Wang, Qiao Shi
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (7): 455–471.
DOI: https://doi.org/10.1042/CS20211031
Published: 06 April 2022
...Ning Hu; Xiaoyi Zhang; Xuanzhe Zhang; Yongjun Guan; Ruyuan He; Enfu Xue; Xiaoyi Zhang; Wenhong Deng; Jia Yu; Weixing Wang; Qiao Shi Acute pancreatitis (AP) is an acute inflammatory disorder characterized by acinar cell death and inflammation. Multiple factors cause hyperglycemia after AP...
View article titled, Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span>
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Includes: Supplementary data
Articles

Decreased HLA (human leucocyte antigen)-DR expression on peripheral blood monocytes predicts the development of organ failure in patients with acute pancreatitis

Panu MENTULA, Marja-Leena KYLÄNPÄÄ-BÄCK, Esko KEMPPAINEN, Annika TAKALA, Sten-Erik JANSSON, Hannu KAUTIAINEN, Pauli PUOLAKKAINEN, Reijo HAAPIAINEN, Heikki REPO
Journal: Clinical Science
Clin Sci (Lond) (2003) 105 (4): 409–417.
DOI: https://doi.org/10.1042/CS20030058
Published: 01 October 2003
...Panu MENTULA; Marja-Leena KYLÄNPÄÄ-BÄCK; Esko KEMPPAINEN; Annika TAKALA; Sten-Erik JANSSON; Hannu KAUTIAINEN; Pauli PUOLAKKAINEN; Reijo HAAPIAINEN; Heikki REPO Immune suppression plays an important role in the pathogenesis of acute pancreatitis. Monocyte expression of HLA (human leucocyte antigen...
View article titled, Decreased HLA (human leucocyte antigen)-DR expression on peripheral blood monocytes predicts the development of organ failure in patients with <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span>
Click here to open pdf in another window PDF for Decreased HLA (human leucocyte antigen)-DR expression on peripheral blood monocytes predicts the development of organ failure in patients with <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span>
Articles

Cholecystokinin blockade triggers earlier and enhanced intra-acinar oxygen free radical generation in acute pancreatitis induced by pancreatic duct obstruction in rats

Aránzazu URUÑUELA, Manuel A. MANSO, Ana M. DE LA MANO, Isabel DE DIOS
Journal: Clinical Science
Clin Sci (Lond) (2003) 105 (2): 203–212.
DOI: https://doi.org/10.1042/CS20030072
Published: 01 August 2003
...Aránzazu URUÑUELA; Manuel A. MANSO; Ana M. DE LA MANO; Isabel DE DIOS Cholecystokinin (CCK) has been suggested to be a contributory mediator in acute pancreatitis (AP). The aim of the present study was to assess the role of CCK in the development of oxidative stress at different stages of AP...
View article titled, Cholecystokinin blockade triggers earlier and enhanced intra-acinar oxygen free radical generation in <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span> induced by pancreatic duct obstruction in rats
Click here to open pdf in another window PDF for Cholecystokinin blockade triggers earlier and enhanced intra-acinar oxygen free radical generation in <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span> induced by pancreatic duct obstruction in rats
Articles

Asynchronous impairment of calcium homoeostasis in different acinar cells after pancreatic duct obstruction in rat

Aránzazu URUÑUELA, Manuel A. MANSO, Ana Ma DE LA MANO, Sara SEVILLANO, Alberto ORFAO, Isabel DE DIOS
Journal: Clinical Science
Clin Sci (Lond) (2002) 102 (6): 615–622.
DOI: https://doi.org/10.1042/cs1020615
Published: 30 April 2002
...Aránzazu URUÑUELA; Manuel A. MANSO; Ana Ma DE LA MANO; Sara SEVILLANO; Alberto ORFAO; Isabel DE DIOS Current evidence suggests that alterations within acinar cells are responsible for the development of acute pancreatitis. After inducing acute pancreatitis in rats by pancreatic duct obstruction, we...
View article titled, Asynchronous impairment of calcium homoeostasis in different acinar cells after pancreatic duct obstruction in rat
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Articles

Enzyme load in pancreatic acinar cells is increased in the early stages of acute pancreatitis induced by duct obstruction in rats

Aránzazu URUÑUELA, Manuel A. MANSO, Rosa M PINTO, Alberto ORFAO, Isabel DE DIOS
Journal: Clinical Science
Clin Sci (Lond) (2000) 98 (2): 143–150.
DOI: https://doi.org/10.1042/cs0980143
Published: 04 January 2000
...Aránzazu URUÑUELA; Manuel A. MANSO; Rosa M PINTO; Alberto ORFAO; Isabel DE DIOS Trypsinogen and amylase content has been analysed by flow cytometry in individual pancreatic cells from rats with acute pancreatitis induced by pancreatic duct obstruction, from the earliest stages to 48 h after...
View article titled, Enzyme load in pancreatic acinar cells is increased in the early stages of <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span> induced by duct obstruction in rats
Click here to open pdf in another window PDF for Enzyme load in pancreatic acinar cells is increased in the early stages of <span class="search-highlight">acute</span> <span class="search-highlight">pancreatitis</span> induced by duct obstruction in rats
Articles

Changes in Both the Membrane and the Enzyme Content of Individual Zymogen Granules are Associated with Sodium Taurocholate-Induced Pancreatitis in Rats

Manuel A. Manso, Alberto Orfao, M. Dolores Tabernero, Secundino Vicente, Isabel De Dios
Journal: Clinical Science
Clin Sci (Lond) (1998) 94 (3): 293–301.
DOI: https://doi.org/10.1042/cs0940293
Published: 01 March 1998
...Manuel A. Manso; Alberto Orfao; M. Dolores Tabernero; Secundino Vicente; Isabel De Dios 1. After monitoring the changes associated with necrotizing acute pancreatitis in rats from early stages to 24 h after infusion of 5% sodium taurocholate in the choledocus, we characterized by flow cytometry...
View article titled, Changes in Both the Membrane and the Enzyme Content of Individual Zymogen Granules are Associated with Sodium Taurocholate-Induced Pancreatitis in Rats
Click here to open pdf in another window PDF for Changes in Both the Membrane and the Enzyme Content of Individual Zymogen Granules are Associated with Sodium Taurocholate-Induced Pancreatitis in Rats