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Keywords: Toll-like receptor 4
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Clin Sci (Lond) (2016) 130 (6): 451–461.
Published: 04 February 2016
... clinical benefit. The adjuvant monophosphoryl lipid A (MPLA) is a weak toll-like receptor 4 (TLR4) agonist that induces negligible inflammation but retains potent immunomodulatory properties. We postulated that pre-treatment with MPLA would inhibit the inflammatory response of endothelial cells...
Includes: Supplementary data
Clin Sci (Lond) (2015) 129 (2): 93–105.
Published: 24 April 2015
... Journal compilation © 2015 Biochemical Society 2015 atherosclerosis endothelial progenitor cells miRNA SIRT-1 telomere toll-like receptor 4 As coronary artery disease (CAD) continues to be a leading cause of death around the world, primary and secondary prevention are of great...
Clin Sci (Lond) (2014) 126 (10): 685–694.
Published: 27 January 2014
... diabetic nephropathy inflammation kidney nuclear factor κB (NF-κB) Toll-like receptor 2 Toll-like receptor 4 Diabetic nephropathy is the leading cause of ESKD (end-stage kidney disease), affecting approximately one-third of all patients with diabetes mellitus [ 1 ]. The disease is relentlessly...