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Keywords: Th17
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Clin Sci (Lond) (2021) 135 (22): 2541–2558.
Published: 26 November 2021
... were attenuated in Redd1 −/− mice. Mechanistically, REDD1 in GECs regulated CXCL1 production, which attracted MHCII + monocytes migration by CXCL1-CXCR2 axis. Then H. pylori induced MHCII + monocytes to secrete IL-23, which favored IL-17A-producing CD4 + cell (Th17 cell) polarization, thereby...
Includes: Supplementary data
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Clin Sci (Lond) (2020) 134 (15): 2075–2090.
Published: 13 August 2020
... and in vitro mixed culture system. Microglia overexpressing CD200R produced less inflammatory chemokines and reduced the loss of TH + neurons. In addition, HMGB1 A box decreased the level of CCL5 and significantly inhibited the infiltration of almost all T cells including Th17 and the proportion of Th17 in CD4...
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Clin Sci (Lond) (2014) 126 (5): 347–354.
Published: 01 November 2013
... effect reported in patients with recurrent miscarriage. However, studies on maternal peripheral blood are conflicting. In the present study, we characterized the maternal CD4 T-cell effector subsets, including the recently described Th17 subset, during normal pregnancy (cross-sectional cohort, n =71...