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Keywords: Pressure Overload
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Articles
Clin Sci (Lond) (2022) 136 (2): 181–196.
Published: 28 January 2022
... activation and mitochondrial depolarization. Thus, our results demonstrate that NRK-2 plays protective roles in pressure overload (PO)-induced dilatative cardiac remodeling and, genetic ablation exacerbates dilated cardiomyopathy (DCM), interstitial collagen deposition, and cardiac dysfunction post-TAC due...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2017) 131 (10): 935–949.
Published: 04 May 2017
...Vanessa Arrieta; Ernesto Martinez-Martinez; Jaime Ibarrola; Virginia Alvarez; Rafael Sádaba; Amaia Garcia-Peña; Amaya Fernández-Celis; Victoria Cachofeiro; Patrick Rossignol; Natalia López-Andrés Aortic stenosis (AS) is characterized by pressure overload and causes left ventricular (LV) fibrosis...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2016) 130 (22): 2061–2071.
Published: 14 October 2016
... overload-induced cardiac remodelling. OX40 KO mice with reconstituted CD4 + T-lymphocytes presented deteriorated cardiac remodelling. OX40 alters the pathology of cardiac remodelling via the modulation of CD4 + T-cell function. Ang II cardiac remodelling CD4 + T-lymphocytes OX40 pressure...
Articles
Clin Sci (Lond) (2015) 128 (10): 665–678.
Published: 20 February 2015
..., but it remains inconclusive whether this gene promotes or inhibits cell apoptosis. In the present study, we attempted to investigate the role of Ankrd1 on AngII (angiotensin II)- or pressure-overload-induced cardiomyocyte apoptosis. In the failing hearts of mice with pressure overload, the protein expression...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2014) 126 (7): 497–506.
Published: 11 December 2013
... of the enzymatic systems involved in extracellular collagen type I synthesis and deposition. cardiac remodelling miR-122 myocardial fibrosis pressure overload procollagen C-terminal proteinase enhancer-1 (PCPE-1) transforming growth factor-β type 1 (TGF-β 1 ) • The present study...
Articles
Clin Sci (Lond) (2013) 125 (6): 291–300.
Published: 22 May 2013
... differentially contribute to cardiac pathophysiology. Animal studies show uncertain results regarding the regulation of cardiac Nox4 by pressure overload and no data are available on human myocardial Nox4. In the present study, we evaluated Nox4 expression and its relationship with myocardial remodelling and LV...
Articles
Clin Sci (Lond) (2010) 118 (2): 137–145.
Published: 19 October 2009
...Xiaojian Wang; Xu Yang; Kai Sun; Jingzhou Chen; Xiaodong Song; Hu Wang; Zhe Liu; Changxin Wang; Channa Zhang; Rutai Hui GDF15 (growth-differentiation factor 15) is a novel antihypertrophic factor which is induced in the heart in response to pressure overload and plays an important regulatory role...
Includes: Supplementary data