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Keywords: Osteopontin
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Clin Sci (Lond) (2022) 136 (9): 643–656.
Published: 04 May 2022
...-like macrophage aggregates and reduced their capacity of producing pro-fibrogenic mediators like osteopontin (OPN) and galectin-3 (Gal-3). This effect was related to an interference with the acquisition of a specific macrophage phenotype characterized by the expression of the Triggering Receptor...
Includes: Supplementary data
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Clin Sci (Lond) (2016) 130 (19): 1727–1739.
Published: 23 August 2016
... role in the regulation of sodium and potassium homoeostasis by binding to the mineralocorticoid receptor and contributes to kidney and cardiovascular damage. Aldosterone has been reported to induce IL-18, resulting in cardiac fibrosis with induced IL-18-mediated osteopontin (OPN). We therefore...
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Clin Sci (Lond) (2006) 111 (5): 319–324.
Published: 13 October 2006
...Mie Kurata; Takafumi Okura; Sanae Watanabe; Tomikazu Fukuoka; Jitsuo Higaki OPN (osteopontin), a pro-inflammatory cytokine, has recently emerged as a key factor in both vascular remodelling and the development of atherosclerosis. However, the relationship between OPN and atherosclerosis in patients...