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Keywords: Orai1
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Articles
Seamus Grundy, Manminder Kaur, Jonathan Plumb, Sophie Reynolds, Simon Hall, David House, Malcolm Begg, David Ray, Dave Singh
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (3): 223–232.
Published: 09 October 2013
... pulmonary disease (COPD) nuclear factor of activated T-cells (NFAT) ORAI1 • Currently available anti-inflammatory therapies have limited efficacy in COPD and therefore there is a need for novel anti-inflammatory treatments. • In the present study, we show that targeting CD8 cells from COPD...
Includes: Supplementary data
Articles
Fernanda R. C. Giachini, Victor V. Lima, Fernando P. Filgueira, Anne M. Dorrance, Maria Helena C. Carvalho, Zuleica B. Fortes, R. Clinton Webb, Rita C. Tostes
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (5): 215–226.
Published: 28 October 2011
...-related differences in SOCE (store-operated Ca 2+ entry) have been minimally investigated. We hypothesized that vascular protection in females, compared with males, reflects decreased Ca 2+ mobilization due to diminished activation of Orai1/STIM1 (stromal interaction molecule 1). In addition, we...
