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Keywords: Nicotinamide riboside
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Dong Zheng, Yi Zhang, Ming Zheng, Ting Cao, Grace Wang, Lulu Zhang, Rui Ni, Joseph Brockman, Huiting Zhong, Guo-Chang Fan, Tianqing Peng
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (13): 1505–1521.
Published: 15 July 2019
... cardiotoxicity. The present study investigated whether nicotinamide riboside (NR), a precursor of nicotinamide adenine dinucleotide (NAD) + , prevents DOX cardiotoxicity by improving autophagic flux. We report that administration of NR elevated NAD + levels, and reduced cardiac injury and myocardial dysfunction...
Includes: Supplementary data