..., in part, to increased JNK activation and mitochondrial dysfunction. Correspondence: Firdos Ahmad ( fahmad@sharjah.ac.ae ) 06 10 2021 18 01 2022 20 01 2022 20 01 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022...

... 2021 13 07 2021 16 07 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 epigenetics intrauterine growth restriction mitochondrial dysfunction oxidative stress sex Figure 1 Mitochondrion-nucleus crosstalk...

... Ritter; Felipe Dal-Pizzol Background: Several different mechanisms have been proposed to explain long-term cognitive impairment in sepsis survivors. The role of persisting mitochondrial dysfunction is not known. We thus sought to determine whether stimulation of mitochondrial dynamics improves...

... design of effective strategies to delay or treat DCM. Mitochondrial dysfunction is recognized as the driving force for the pathogenesis of DCM; therefore, maintaining cardiac mitochondrial quality is crucial for DCM prevention. Mitophagy is the process by which cells degrade abnormal or superfluous...

... stress heart failure iron deficiency iron overload lipocalin 2 (Lcn2) mitochondrial dysfunction NGAL oxidative stress Free iron is highly-redox reactive and can participate in a redox reaction that leads to the generation of reactive oxygen species (ROS). ROS include not only a range...

...José Magalhães; Rita Ferreira; Maria J. Neuparth; Paulo J. Oliveira; Franklim Marques; António Ascensão In the present study, the effect of vitamin E (α-tocopherol) on mice skeletal muscle mitochondrial dysfunction and oxidative damage induced by an in vivo acute and severe hypobaric hypoxic insult...