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Keywords: Mitochondrial dysfunction
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Clin Sci (Lond) (2022) 136 (2): 181–196.
Published: 28 January 2022
..., in part, to increased JNK activation and mitochondrial dysfunction. Correspondence: Firdos Ahmad ( fahmad@sharjah.ac.ae ) 06 10 2021 18 01 2022 20 01 2022 20 01 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022...
Includes: Supplementary data
Clin Sci (Lond) (2016) 130 (17): 1511–1521.
Published: 18 July 2016
... design of effective strategies to delay or treat DCM. Mitochondrial dysfunction is recognized as the driving force for the pathogenesis of DCM; therefore, maintaining cardiac mitochondrial quality is crucial for DCM prevention. Mitophagy is the process by which cells degrade abnormal or superfluous...
Clin Sci (Lond) (2015) 129 (10): 851–862.
Published: 28 August 2015
... stress heart failure iron deficiency iron overload lipocalin 2 (Lcn2) mitochondrial dysfunction NGAL oxidative stress Free iron is highly-redox reactive and can participate in a redox reaction that leads to the generation of reactive oxygen species (ROS). ROS include not only a range...