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Keywords: MDM2
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CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2

Xudong Wang, Yanshi Li, Min Pan, Tao Lu, Min Wang, Zhihai Wang, Chuan Liu, Guohua Hu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1691–1710.
https://doi.org/10.1042/CS20220581
Published: 25 November 2022
... inhibited LN metastasis. In conclusions, CEACAM5 inhibited epithelial–mesenchymal transition (EMT) in HNSCC by reducing murine double minute 2 (MDM2) expression and thereby suppressing LN metastasis. CEACAM5 has potential as both a prognostic marker and a therapeutic target in HNSCC. To knock down...
View article titled, CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting <span class="search-highlight">MDM2</span>
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Includes: Supplementary data