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Keywords: Hepatocellular carcinoma
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Clin Sci (Lond) (2022) 136 (5): 323–328.
Published: 02 March 2022
... pathologies. Specifically, the authors profiled circulating miRNAs in patients with hepatocellular carcinoma (HCC), liver cirrhosis (LC), and healthy controls and found that serum miR - 885 - 5p levels were significantly higher in samples of patients with HCC (6.5-fold increase) and LC (8.8-fold increase...
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Clin Sci (Lond) (2020) 134 (12): 1457–1472.
Published: 18 June 2020
...Yongjie Zhou; Qing Xu; Lv Tao; Yuwei Chen; Yuke Shu; Zhenru Wu; Changli Lu; Yujun Shi; Hong Bu The chromatin remodeling complex SWI/SNF regulates the accessibility of target genes to transcription factors and plays a critical role in the tumorigenesis of hepatocellular carcinoma (HCC). The SWI/SNF...
Includes: Supplementary data
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Clin Sci (Lond) (2019) 133 (19): 2019–2022.
Published: 11 October 2019
...Brittany Dewdney; Lionel Hebbard Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related deaths around the globe. For patients receiving liver tumour resection, the risk of reoccurrence and metastasis is high. Cancer metastasis can occur as a consequence of a physical...
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Clin Sci (Lond) (2017) 131 (1): 27–36.
Published: 09 December 2016
... antineoplastic properties. For metabolic syndrome patients with hepatocellular carcinoma (HCC), metformin may provide antitumoral effects. We evaluated the impact of metformin on tumour growth and visceral fat composition using relevant preclinical models of metabolic syndrome. Studies were performed in three...
Includes: Supplementary data
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Clin Sci (Lond) (2016) 130 (13): 1125–1136.
Published: 23 May 2016
...Junjie Xiao; Qi Sun; Yihua Bei; Ling Zhang; Jasmina Dimitrova-Shumkovska; Dongchao Lv; Yuefeng Yang; Yan Cao; Yingying Zhao; Meiyi Song; Yang Song; Fei Wang; Changqing Yang Hepatocellular carcinoma (HCC) represents a leading cause of deaths worldwide. Novel therapeutic targets for HCC are needed...
Includes: Supplementary data
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Clin Sci (Lond) (2010) 118 (12): 691–705.
Published: 30 March 2010
... in the maintenance of liver homoeostasis as well as in the pathogenesis of a wide variety of conditions affecting the liver, including viral hepatitis, steatohepatitis, cirrhosis and hepatocellular carcinoma. Much of the current knowledge of NF-κB signalling in the liver relates to the canonical pathway, the IKK...
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Clin Sci (Lond) (2008) 114 (1): 73–83.
Published: 30 November 2007
.... Quantification of immunoreactive proteins was obtained by densitometry using the Gel Doc 2000 device and software (Bio-Rad Laboratories). cell cycle S -farnesylthiosalicylic acid (FTS) hepatocellular carcinoma liver mitogen-activated protein kinase (MAPK) partial hepatectomy Ras...
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Clin Sci (Lond) (1994) 86 (4): 447–451.
Published: 01 April 1994
..., such as hepatocellular carcinoma or liver cirrhosis caused by chronic viral hepatitis, and correlated with reduced albumin levels in these conditions, indicating that the liver is the site of phosphoinositol-specific phospholipase D synthesis and that phosphoinositol-specific phospholipase D may be used as an additional...
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Clin Sci Mol Med (1973) 45 (3): 387–396.
Published: 01 September 1973
...A. I. Vinik; W. Pooler 1. Responses to a 50 g oral glucose load and intravenous administration of 1 g of sodium tolbutamide have been compared in thirteen patients with hepatocellular carcinoma and ten control subjects. 2. The hepatoma patients have lower basal plasma glucose and immunoreactive...