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Keywords: HIF-1α-Twist signaling pathway
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Articles

Overexpression of TrpC5 promotes tumor metastasis via the HIF-1α–Twist signaling pathway in colon cancer

Zhen Chen, Yaodan Zhu, Yongfei Dong, Peng Zhang, Xiping Han, Jian Jin, Xin Ma
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (19): 2439–2450.
https://doi.org/10.1042/CS20171069
Published: 22 September 2017
... displayed poorer overall and metastasis-free survival. Taken together, our findings demonstrate that TrpC5 induces the EMT through the HIF-1α–Twist signaling pathway to promote tumor metastasis in colon cancer. siHIF-1α-1 (forward, 5′-CUGAUGACCAGCAACUUGA-3′, reverse 5′-UCAAGUUGCUGGUCAUCAG-3′) siHIF...
View article titled, Overexpression of TrpC5 promotes tumor metastasis via the <span class="search-highlight">HIF</span>-<span class="search-highlight">1α</span>–<span class="search-highlight">Twist</span> <span class="search-highlight">signaling</span> <span class="search-highlight">pathway</span> in colon cancer
Open the PDF for Overexpression of TrpC5 promotes tumor metastasis via the <span class="search-highlight">HIF</span>-<span class="search-highlight">1α</span>–<span class="search-highlight">Twist</span> <span class="search-highlight">signaling</span> <span class="search-highlight">pathway</span> in colon cancer in another window
Includes: Supplementary data