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Keywords: HIF-1α
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Clin Sci (Lond) (2021) 135 (10): 1273–1288.
Published: 26 May 2021
.... Hypoxia inducible factor-1α (HIF-) can promote renal fibrosis in some kidney diseases, but its role in Cis-induced CKD is still unknown. Notch-1 is a recognized molecule that promotes renal fibrosis under pathological circumstances, and evidence shows that HIF- and Notch-1 are closely related to each...
Clin Sci (Lond) (2020) 134 (13): 1573–1592.
Published: 30 June 2020
... protein expression was down-regulated in the kidney tissues of db/db mice as well as in high glucose (HG)-induced NRK-52E cells. Overexpression of Cx43 improved renal function in db/db spontaneous diabetic model mice, increased SIRT1 levels, decreased hypoxia-inducible factor (HIF)- expression...
Clin Sci (Lond) (2002) 103 (s2002): 210S–214S.
Published: 01 September 2002
...-3-phosphate dehydrogenase (GAPDH) and hypoxia-inducible factor-1α (HIF-), but not that of peroxisome-proliferator-activated receptor-γ co-activator, suggesting that electrical stimulation suppresses the glycolytic system. Furthermore, a higher oxygen content (50%) decreased drastically...