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Keywords: HIF
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Clin Sci (Lond) (2021) 135 (14): 1707–1726.
Published: 22 July 2021
... the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia-inducible factor (HIF) is reported to protect the kidney from acute ischemic damage and a novel HIF stabilizer, FG4592 (Roxadustat), has become available in the clinic...
Includes: Supplementary data