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Keywords: Extracellular VesiclesClose
Soumyalekshmi Nair, Valeska Ormazabal, Flavio Carrion, Aase Handberg, H David McIntyre, Carlos Salomon
Clin Sci (Lond) (2023) 137 (16): 1311–1332.
Published: 31 August 2023
...Soumyalekshmi Nair; Valeska Ormazabal; Flavio Carrion; Aase Handberg; H David McIntyre; Carlos Salomon Extracellular vesicles (EVs) are critical mediators of cell communication, playing important roles in regulating molecular cross-talk between different metabolic tissues and influencing insulin...
Clin Sci (Lond) (2023) 137 (3): 281–301.
Published: 10 February 2023
...Javier Gonzalez Fernandez; Javier Moncayo Arlandi; Ana Ochando; Carlos Simon; Felipe Vilella Embryo–maternal cross-talk has emerged as a vitally important process for embryo development and implantation, which is driven by secreted factors and extracellular vesicles (EVs). The EV cargo of bioactive...
Clin Sci (Lond) (2022) 136 (24): 1873–1875.
Published: 22 December 2022
...Agafe Bless Reyes; Dylan Burger In a recent article published in Clinical Science , James-Allan et al. examined the effect of small extracellular vesicles (EVs) on glucose intolerance in pregnancy. This editorial commentary summarizes major findings from this study and discusses the impact on our...
Toluwalase Awoyemi, Ana Sofia Cerdeira, Wei Zhang, Shuhan Jiang, Maryam Rahbar, Prassana Logenthiran, Christopher Redman, Manu Vatish
Clin Sci (Lond) (2022) 136 (24): 1793–1807.
Published: 13 December 2022
... by the participation of University of Oxford in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC. Extracellular vesicles nanoparticles Placenta Preeclampsia STB-EVs syncytiotrophoblast Preeclampsia (PE...
Clin Sci (Lond) (2022) 136 (20): 1439–1447.
Published: 21 October 2022
... capacity to inhibit entry of the virus into cells. Elsewhere, several drugs, including calpeptin, were found to be able to inhibit extracellular vesicle (EV) biogenesis. Unsurprisingly, because of similarities between viral and EV release mechanisms, calpeptin has also been shown to inhibit viral egress...
Clin Sci (Lond) (2021) 135 (12): 1487–1503.
Published: 17 June 2021
..., and the initiating mechanisms remain incompletely understood. More recently, circulating inflammatory markers, cardiac biomarkers, microRNAs, and extracellular vesicles (EVs) have been considered as early markers of cardiovascular injury. Concomitantly, the role of the endothelium in regulating cardiac function...
Jack D. Beazer, Patamat Patanapirunhakit, Jason M.R. Gill, Delyth Graham, Helen Karlsson, Stefan Ljunggren, Monique T. Mulder, Dilys J. Freeman
Clin Sci (Lond) (2020) 134 (22): 2977–2986.
Published: 19 November 2020
.... However, the gold standard density ultracentrifugation technique used in the isolation of HDL also co-isolates extracellular vesicles (EVs). EVs are ubiquitous cell-derived particles with lipid bilayers that carry a number of lipids, proteins and DNA/RNA/miRNAs involved in cell-to-cell communication. EVs...
Clin Sci (Lond) (2020) 134 (20): 2741–2754.
Published: 28 October 2020
...Xia-Qing Li; Lilach O. Lerman; Yu Meng Extracellular vesicles (EVs) are membrane-bound vesicles released by most cells and are found in diverse biological fluids. The release of EVs provides a new mechanism for intercellular communication, allowing cells to transfer their functional cargoes...
Clin Sci (Lond) (2020) 134 (12): 1301–1304.
Published: 16 June 2020
... the progression of infection and reducing lung injury. Another way, discussed here, to capture SARS-CoV-2, as an adjunct or alternative, would be to use ACE2 + -small extracellular vesicles (sEVs). A competitive inhibition therapy could therefore be developed, using sEVs from engineered mesenchymal stromal/stem...
Clin Sci (Lond) (2020) 134 (2): 169–192.
Published: 23 January 2020
... be packaged and secreted in extracellular vesicles (EVs), where they participate in cell–cell communication. The measurement of EV-encapsulated miRNAs in the circulation may inform disease mechanisms occurring in the plaque itself, and therefore may serve as sentinels of unstable plaque as well as therapeutic...
Jin Cai, Weiwei Guan, Xiaorong Tan, Caiyu Chen, Liangpeng Li, Na Wang, Xue Zou, Faying Zhou, Jialiang Wang, Fang Pei, Xinjian Chen, Hao Luo, Xinquan Wang, Duofen He, Lin Zhou, Pedro A. Jose, Chunyu Zeng
Clin Sci (Lond) (2015) 129 (3): 259–269.
Published: 08 May 2015
... (extracellular vesicles) is involved in the pathogenesis of atherosclerosis. PCR and gene sequencing found the SRY gene fragment in plasma EVs from male, but not female, patients; EVs from male patients with CAD (coronary artery disease) had a higher SRY GCN (gene copy number) than healthy subjects. Additional...