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Keywords: ECE
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Clin Sci (Lond) (2002) 103 (s2002): 98S–101S.
Published: 01 September 2002
...) is a potent vasorelaxant and diuretic agent, which is mainly degraded by neutral endopeptidase 24.11 (NEP) in vivo . Thus, compounds that can suppress the biosynthesis of ETs by inhibiting endothelin converting enzymes (ECEs), which catalyse the final step of post-translational processing...
Clin Sci (Lond) (2002) 103 (s2002): 206S–209S.
Published: 01 September 2002
...Andrew T. GOODWIN; Mahboob A. KHAN; Adrian H. CHESTER; Mohamed AMRANI; Magdi H. YACOUB Endothelin-1 (ET-1) is believed to play an important role in cardiac ischaemia/reperfusion injury. ET-1 is synthesized from preproET-1 by the action of ET-converting enzyme (ECE). It is unclear to what extent...