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Keywords: DNA damage
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Clin Sci (Lond) (2022) 136 (1): 163–166.
Published: 10 January 2022
...Sarah-Eve Lemay; Sebastien Bonnet; François Potus In this commentary, we discuss new observations stating that spliced X-box-binding protein 1 (Xbp1s)-DNA damage-inducible transcript 3 (Ddit3) promotes monocrotaline (MCT)-induced pulmonary hypertension (Jiang et al., Clinical Science (2021) 135 (21...
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Clin Sci (Lond) (2016) 130 (14): 1269–1284.
Published: 13 June 2016
... levels of oxidative stress and significantly lower levels of antioxidant activity leading to molecular damage, including protein nitration, lipid peroxidation and DNA damage that contribute to tissue dysfunction. Furthermore, we show that elastase is elevated, suggesting that elastin is degraded...
Includes: Supplementary data
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Clin Sci (Lond) (2004) 107 (4): 355–364.
Published: 24 September 2004
... malexeye@jaguar1.usouthal.edu ). 26 5 2004 22 7 2004 28 7 2004 28 7 2004 The Biochemical Society 2004 aging DNA damage mitochondrial DNA oxidative stress reactive oxygen species repair Aging can be defined as a multifactorial phenomenon characterized by a time...
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