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Correction: Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway -Application to a biomarker for atherosclerosis

Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (5): 353.
https://doi.org/10.1042/CS-2022-0525_COR
Published: 01 March 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker cell-free DNA cGAS-STING DNA damage mitochondria...
View article titled, Correction: Cigarette smoke induces mitochondrial <span class="search-highlight">DNA</span> <span class="search-highlight">damage</span> and activates cGAS-STING pathway -Application to a biomarker for atherosclerosis
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Articles

Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis

Keitaro Ueda, Chiemi Sakai, Takafumi Ishida, Kosuke Morita, Yusuke Kobayashi, Yasunori Horikoshi, Akiko Baba, Yuma Okazaki, Masao Yoshizumi, Satoshi Tashiro, Mari Ishida
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 163–180.
https://doi.org/10.1042/CS20220525
Published: 24 January 2023
...Keitaro Ueda; Chiemi Sakai; Takafumi Ishida; Kosuke Morita; Yusuke Kobayashi; Yasunori Horikoshi; Akiko Baba; Yuma Okazaki; Masao Yoshizumi; Satoshi Tashiro; Mari Ishida Cigarette smoking is a major risk factor for atherosclerosis. We previously reported that DNA damage was accumulated...
View article titled, Cigarette smoke induces mitochondrial <span class="search-highlight">DNA</span> <span class="search-highlight">damage</span> and activates cGAS-STING pathway: application to a biomarker for atherosclerosis
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Includes: Supplementary data
Articles

Commentary on: Xbp1s-Ddit3, DNA damage and pulmonary hypertension

Sarah-Eve Lemay, Sebastien Bonnet, François Potus
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 163–166.
https://doi.org/10.1042/CS20211095
Published: 10 January 2022
...Sarah-Eve Lemay; Sebastien Bonnet; François Potus In this commentary, we discuss new observations stating that spliced X-box-binding protein 1 (Xbp1s)-DNA damage-inducible transcript 3 (Ddit3) promotes monocrotaline (MCT)-induced pulmonary hypertension (Jiang et al., Clinical Science (2021) 135 (21...
View article titled, Commentary on: Xbp1s-Ddit3, <span class="search-highlight">DNA</span> <span class="search-highlight">damage</span> and pulmonary hypertension
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Articles

Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction

Paula K. Bautista-Niño, Eliana Portilla-Fernandez, Eloisa Rubio-Beltrán, Janette J. van der Linden, René de Vries, Richard van Veghel, Martine de Boer, Matej Durik, Yanto Ridwan, Renata Brandt, Jeroen Essers, Robert I. Menzies, Rachel Thomas, Alain de Bruin, Dirk J. Duncker, Heleen M.M. van Beusekom, Mohsen Ghanbari, Jan H.J. Hoeijmakers, Radislav Sedlacek, Rhian M. Touyz, Augusto C. Montezano, Ingrid van der Pluijm, A.H. Jan Danser, Kristian A. Haanes, Anton J.M. Roks
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (7): 727–746.
https://doi.org/10.1042/CS20190124
Published: 07 April 2020
... which vascular aging outcomes are due to local endothelial DNA damage, which was accomplished by genetic removal of ERCC1 (excision repair cross-complementation group 1) DNA repair in mice (EC-knockout (EC-KO) mice). EC-KO showed a progressive decrease in microvascular dilation of the skin, increased...
View article titled, Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction
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Includes: Supplementary data
Articles

Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing

Sandeep Dhall, Raquelle Alamat, Anthony Castro, Altaf H. Sarker, Jian-Hua Mao, Alex Chan, Bo Hang, Manuela Martins-Green
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (14): 1269–1284.
https://doi.org/10.1042/CS20160236
Published: 13 June 2016
... levels of oxidative stress and significantly lower levels of antioxidant activity leading to molecular damage, including protein nitration, lipid peroxidation and DNA damage that contribute to tissue dysfunction. Furthermore, we show that elastase is elevated, suggesting that elastin is degraded...
View article titled, Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing
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Includes: Supplementary data
Articles

Oxidative stress, antioxidant status and DNA damage in patients with impaired glucose regulation and newly diagnosed Type 2 diabetes

Fangfang Song, Wenbo Jia, Ying Yao, Yafei Hu, Lin Lei, Jie Lin, Xiufa Sun, Liegang Liu
Journal: Clinical Science
Clin Sci (Lond) (2007) 112 (12): 599–606.
https://doi.org/10.1042/CS20060323
Published: 14 May 2007
... diabetes, to test this hypothesis, we have investigated oxidative stress pathways and DNA damage in patients with IGR and newly diagnosed Type 2 diabetes. The study population consisted of 92 subjects with NGT (normal glucose tolerance), 78 patients with IGR and 113 patients with newly diagnosed diabetes...
View article titled, Oxidative stress, antioxidant status and <span class="search-highlight">DNA</span> <span class="search-highlight">damage</span> in patients with impaired glucose regulation and newly diagnosed Type 2 diabetes
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Articles

Mitochondrial DNA and aging

Mikhail F. ALEXEYEV, Susan P. LeDOUX, Glenn L. WILSON
Journal: Clinical Science
Clin Sci (Lond) (2004) 107 (4): 355–364.
https://doi.org/10.1042/CS20040148
Published: 24 September 2004
... malexeye@jaguar1.usouthal.edu ). 26 5 2004 22 7 2004 28 7 2004 28 7 2004 The Biochemical Society 2004 aging DNA damage mitochondrial DNA oxidative stress reactive oxygen species repair Aging can be defined as a multifactorial phenomenon characterized by a time...
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Articles

Increased DNA oxidative susceptibility without increased plasma LDL oxidizability in Type II diabetes: effects of α-tocopherol supplementation

Michael J. SAMPSON, Sian ASTLEY, Tristan RICHARDSON, Gavin WILLIS, Isabel R. DAVIES, David A. HUGHES, Sue SOUTHON
Journal: Clinical Science
Clin Sci (Lond) (2001) 101 (3): 235–241.
https://doi.org/10.1042/cs1010235
Published: 03 August 2001
... The Biochemical Society and the Medical Research Society © 2001 2001 DNA damage paraoxonase -tocopherol Type II diabetes 235Clinical Science (2001) 101, 235 241 (Printed in Great Britain) Increased DNA oxidative susceptibility without increased plasma LDL oxidizability in Type II diabetes: effects...
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