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Keywords: Cardiac myocyte
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Clin Sci (Lond) (2020) 134 (7): 885–888.
Published: 14 April 2020
... be determined by Drp1 [ 9 ]. During I/R, Bax translocates to the mitochondria and controls permeability of the mitochondrial outer membrane and cytochrome c release. In cardiac myocytes, DNA-dependent protein kinase catalytic subunit (DNA-PKcs) may promote I/R injury by suppressing Bax inhibitor-1 (BI-1...
Clin Sci (Lond) (2009) 116 (5): 391–399.
Published: 02 February 2009
... with increased signalling via G-protein-coupled receptors. Three members of the RGS (regulator of G-protein signalling) superfamily RGS2, RGS4 and RGS5 have been implicated in the attenuation of G-protein signalling pathways in vascular and cardiac myocytes, as well as cells of the kidney and autonomic nervous...
Clin Sci (Lond) (2009) 116 (5): 377–389.
Published: 02 February 2009
..., and autocrine and paracrine functions. Laminar shear stress exerts anti-apoptotic, anti-atherosclerotic and antithrombotic effects on ECs (endothelial cells). Mechanical stretch of cardiac myocytes can modulate growth, apoptosis, electric remodelling, alterations in gene expression, and autocrine and paracrine...