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Keywords: CD4+ T-cells
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Articles

The ligands of translocator protein inhibit human Th1 responses and the rejection of murine skin allografts

Yannan Zhang, Sifei Yu, Xiaomin Li, Binyan Yang, Changyou Wu
Journal: Clinical Science
Clin Sci (Lond) (2017) 131 (4): 297–308.
DOI: https://doi.org/10.1042/CS20160547
Published: 30 January 2017
..., FGIN1-27 and Ro5-4864, suppressed the cytokine production in a dose-dependent manner by purified human CD4 + T-cells from peripheral blood mononuclear cells (PBMCs) after stimulation. TSPO ligands inhibited the production of interferon γ (IFN-γ) by memory CD4 + T-cells and the differentiation of naïve...
View article titled, The ligands of translocator protein inhibit human Th1 responses and the rejection of murine skin allografts
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Includes: Supplementary data
Articles

Aberrantly methylated DNA regions lead to low activation of CD4 + T-cells in IgA nephropathy

Fabio Sallustio, Grazia Serino, Sharon N. Cox, Alessandra Dalla Gassa, Claudia Curci, Giuseppe De Palma, Barbara Banelli, Gianluigi Zaza, Massimo Romani, Francesco P. Schena
Journal: Clinical Science
Clin Sci (Lond) (2016) 130 (9): 733–746.
DOI: https://doi.org/10.1042/CS20150711
Published: 18 March 2016
.... In this setting, DNA methylation could also be an important factor influencing this disease. We performed a genome-wide screening for DNA methylation in CD4 + T-cells from IgAN patients and found three regions aberrantly methylated influencing genes involved in the response and proliferation of CD4 + T-cells. Two...
View article titled, Aberrantly methylated DNA regions lead to low activation of <span class="search-highlight">CD4</span> + <span class="search-highlight">T</span>-<span class="search-highlight">cells</span> in IgA nephropathy
Open the PDF for Aberrantly methylated DNA regions lead to low activation of <span class="search-highlight">CD4</span> + <span class="search-highlight">T</span>-<span class="search-highlight">cells</span> in IgA nephropathy in another window
Includes: Supplementary data