... There are three new and significant findings from the present study: (i) CRP is not only a biomarker for, but also a pathogenic mediator in, AKI; (ii) CRP promotes AKI by inhibiting G 1 /S-dependent TEC regeneration; and (iii) blockade of CRP signalling attenuates AKI. acute kidney injury (AKI) C-reactive...

...-reactive protein (CRP) inflammation myeloperoxidase (MPO) NO synthase (NOS) oxidative stress Endothelium-derived NO, which is synthesized from arginine by NOS (NO synthase), is an important regulator of vascular homoeostasis. In addition to being a powerful endogenous vasodilator, NO inhibits...

... blood pressure cardiovascular disease childhood C-reactive protein (CRP) ‘Fetal programming’ or the ‘hypothesis of fetal origin of adult diseases’ suggests that stimuli or injuries that occur during the critical periods of development may permanently modify the structure, physiology...

... 29 2 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cardiovascular disease chronic obstructive pulmonary disease (COPD) C-reactive protein (CRP) systemic inflammation vascular endothelial growth factor VEGF) VEGF (vascular endothelial growth factor...

... Society 2007 C-reactive protein (CRP) cytokine inflammation insulin resistance interleukin lipopolysaccharide Type 2 diabetes There is firm evidence that atherosclerosis is an immune-mediated inflammatory disease [ 1 ]. The nature of the atherosclerotic process can be described...

... giovanna.castoldi@unimib.it ). 29 11 2006 1 3 2007 16 3 2007 16 3 2007 © 2007 The Biochemical Society 2007 C-reactive protein (CRP) cytokine inflammation insulin resistance interleukin lipopolysaccharide Type 2 diabetes Epidemiological studies indicate that diabetes...

..., endothelial cell; FC, foam cell; mΦ, macrophage; OC, osteocalcin; OP, osteopontin; Th, T-helper cell. antioxidant cardiovascular disease C-reactive protein (CRP) cytokine exercise inflammation vascular wall It is well established that physically fit individuals have a reduced risk...

... with the ECG data during acquisition. HF power for variability in respiration was calculated with MATLAB, as described above. The Biochemical Society 2007 behavioural relaxation cardiovascular disease C-reactive protein (CRP) heart rate variability inflammation stress Vagal efferent...

...@temple.edu ). 27 2 2006 10 10 2006 25 10 2006 25 10 2006 The Biochemical Society 2007 C-reactive protein (CRP) cytokine interleukin musculoskeletal disorder overuse injury tumour necrosis factor (TNF) upper-body musculoskeletal assessment According to the most...

... 2005 30 3 2005 The Biochemical Society 2005 atherosclerosis C-reactive protein (CRP) interleukin-8 mitogen-activated protein kinase (MAPK) 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor statin Atherosclerosis is currently regarded as a dynamic and progressive...

... to the ethical guidelines of the Declaration of Helsinki, and the study received approval by the Institution's Human Research Committee. atherosclerosis coronary artery disease C-reactive protein (CRP) left ventricular mass index osteoprotegerin Height, weight, waist circumference and the systolic...

...-diabetic patients, which may only partly be explained by traditional risk factors. Our purpose was to compare non-traditional risk factors, such as endothelial function, C-reactive protein (CRP) and adiponectin, in Type II diabetic and non-diabetic patients following AMI (acute myocardial infarction...

... ]. Indeed, recent studies suggest that CRP is not merely a marker of inflammation and atherosclerosis, but actively participates in the lesion formation inducing leucocyte activation [ 5 ]. CD32 receptor C-reactive protein (CRP) endothelium endothelial nitric oxide synthase (eNOS) inflammation...

... (e-mail nsattar@clinmed.gla.ac.uk ). 19 1 2004 26 1 2004 26 1 2004 © 2004 The Biochemical Society 2004 C-reactive protein (CRP) cytokine endothelial function inflammation serum secretory non-pancreatic type II phospholipase A2 (sPLA2) Clinical Science (2004) 106...

... The Biochemical Society 2004 coronary artery disease C-reactive protein (CRP) endothelial function forearm blood flow inflammation secretory non-pancreatic type II phospholipase A2 (sPLA2) Clinical Science (2004) 106, 511 517 (Printed in Great Britain) 511 Elevated secretory non-pancreatic type II...