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Xiao-Yu Liu, Chang-Bo Zheng, Teng Wang, Jian Xu, Meng Zhang, Ling-Shan Gou, Linfang Jin, Xiaowei Qi, Xianhai Zeng, Hongwen Li, Shuqi Qiu, Peng Zhang
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (2): 155–167.
Published: 23 January 2020
... overexpressing cells were resistant to 5-fluorouracil, a drug commonly used to treat cancer. Moreover, knocking down SPZ1 led to the activation of caspase through the deregulation of Bim by ERK1/2, we found that CRC tissues had significantly higher SPZ1 and lower Bim expression, and SPZ1 H Bim L were associated...
Includes: Supplementary data