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Keywords: Autophagic flux
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Dong Zheng, Yi Zhang, Ming Zheng, Ting Cao, Grace Wang, Lulu Zhang, Rui Ni, Joseph Brockman, Huiting Zhong, Guo-Chang Fan, Tianqing Peng
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (13): 1505–1521.
Published: 15 July 2019
... clinical uses. Oxidative stress is one of major contributors to DOX-induced cardiotoxicity. While autophagic flux serves as an important defense mechanism against oxidative stress in cardiomyocytes, recent studies have demonstrated that DOX induces the blockage of autophagic flux, which contributes to DOX...
Includes: Supplementary data
